Showing 4 results for Rousta
Mahbube Khorsandi, Fazlallah Ghofranipour, Alireza Heydarnia, Soghrat Faghihzadeh, Maryam Vafaei, Firouzeh Rousta, Farkhonde Aminshokravi,
Volume 11, Issue 3 (9-2008)
Abstract
Background: There has been an increase in the number of women willing to have a caesarean birth because of their fear of childbirth. It seems the childbirth preparation educational class is a good way to remove or alleviate fears associated with pregnancy and childbirth.This research designed to identify the effect of childbirth preparation classes on childbirth fear on the primiparous women. Methods and Materials: The present study is a clinical trial which was carried out in 2007 at Milad Hospital, with 100 nulliparous pregnant women. Childbirth fear was measured by childbirth attitudes questionnaire. Normal pregnant women in the second trimester with childbirth fear score was 28 or more were randomly selected and dirided into experimental and control group with 50 subject in each qroup. The experimental group attended nine childbirth preparation class sessions and control group received routine antennal care. Results: The mean scored fear of childbirth in case and control group were 39.35±6.96 and 40.71±6.23 respectively. There was not significant difference between two groups. After the sessions, comparing childbirth fear score between two groups in third trimester showed the mean score of childbirth fear among experimental group was lower than control group (29.82+/- 7.18 compare to 38.03+/-9.27), and the differences statistically was significant (p<0.001). Mode of delivery was significantly different between the two groups. Conclusion: Primiparous women attended childbirth preparation classes acquired lower score of childbirth fear in compare to women received routine prenatal care. The results of this research showed relaxation training decreased childbirth fear and increased normal vaginal delivery.
Sepideh Mahinrousta, Heidar Sharafi, Seyed Moayed Alavian, Bita Behnava, Ali Pouryasin,
Volume 15, Issue 7 (December 2012)
Abstract
Background: Nucleos(t)ide analogues, such as lamivudine and adefovir, are effective drugs for treatment of hepatitis B patients. However, long-term treatment with these drugs leads to the emergence of the nucleos(t)ide analogue resistant strains. The impact of nucleos(t)ide analogues on the emergence of HBsAg escape mutations is not clarified. Hence, the aim of this study was to determine HBsAg escape mutations in chronic hepatitis B patients treated with nucleos(t)ide analogues. Materials and Methods:A cross-sectional study was performed on 50 patients with chronic hepatitis B under treatment with nucleos(t)ide analogues (lamivudine and/or adefovir) and 50 naive chronic hepatitis B patients. HBV DNA was extracted from plasma and S gene of virus was amplified by Nested-PCR followed by direct sequencing. HBsAg gene sequence of the samples was evaluated for detection of HBsAg escape mutations. Results: Among the 100 patients, the following HBsAg escape mutations were identified: sQ101H, sG119R, sP120S, sP127S, sA128V, sG130N, sG130R, sT131I, sM133I, and sY134N. The frequency of HBsAg escape mutations in patients under treatment of nucleos(t)ide analogues was 16% and in naïve patients was 6% (p=0.2, OR=2.98). Conclusion:According to the obtained results, there seems to be no association between using nucleos(t)ide analogues and emergence of HBsAg escape mutations.
Mojtaba Asgari, Masoumeh Asle-Rousta, Mohammad Sofiabadi,
Volume 20, Issue 5 (8-2017)
Abstract
Abstract
Background: Diabetes is the most common endocrine disorder that leads to hyperglycemia and hyperlipidemia. Royal jelly is as a bee-collected natural product has diverse biological properties and that is rich in natural antioxidants. The aim of this study was to investigate the effects of royal jelly on serum glucose and lipids profile in streptozotocin induced type 1 diabetic rats.
Materials and Methods: In this experimental study, 40male Wistar rats were divided into 5 groups(8 in each): control, diabetic rats, Glibenclamide, and two groups of royal jelly- treated diabetic. Diabetes was induced in the rats by injection of streptozotocin (60 mg/kg b.w) intraperitoneally. The royal jelly was gavaged at doses of 100 and 200 mg/kg after streptozotocin injection for30 days. At the end of this period, levels of glucose, cholesterol, triglyceride, LDL and HDL in serum were measured.
Results: Royal jelly and Glibenclamide significantly decreased the levels of glucose, cholesterol, triglyceride and LDL in diabetic rats (p<0.01). In addition, significant increase (p<0.01) in HDL level was observed in royal jelly-treating rats in comparison to the diabetic rats.
Conclusion: The results indicated that royal jelly may be used effectively in controlling and attenuating the complications of diabetes. The hypoglycemic and hypolipidemic effects of royal jelly may be due to the presence of antioxidants.
Fatemeh Jalalvand, Masoumeh Asle-Rousta,
Volume 21, Issue 3 (6-2018)
Abstract
Background and Aim: Chronic restraint stress impairs spatial learning and memory. Myrtle (Myrtus communis) has antioxidant, antidiabetic, hepatoprotective and neuroprotective properties. The aim of this study was to investigate the effect of myrtle hydroalcoholic extract on chronic restraint stress-induced spatial learning and memory deficit in adult male Wistar rats.
Materials and Methods: In this experimental study, 80 adult male Wistar rats were allocated to eight groups (10 in each) included control group (intact), myrtle0.75, myrtle1.5, myrtle3 groups (were gavaged with hydroalcoholic extract of myrtle at 0.75, 1.5 and 3 mg/ kg bw doses), stress group (restrained in restrainers for 6 hours per day for 21 consecutive days), stress- myrtle0.75, stress-myrtle1.5 and stress- myrtle3 groups (received myrtle extract at 0.75, 1.5 and 3 mg/ kg bw doses and exposed to chronic immobility stress). Spatial learning and memory were examined through the Morris water maze test.
Findings: Chronic immobilization stress caused spatial learning and memory impairment. Consuming doses 1.5 and 3 of Myrtle extract to stressed animals caused significant decrease in spent time and swam distance to reach the hidden platform (p<0.05) and increased time lapsed in target quadrant comparing with stress group (p<0.05).
Conclusion: It has been concluded that myrtle extract can improve spatial learning and memory in rats exposed to stress in a dose dependent manner.
