Showing 14 results for Rosta
Akbar Rostaminejad, Zohreh Karimi,
Volume 5, Issue 3 (Autumn 2002)
Abstract
Material and methods: This is a Double blind Randomized clinical trial study which was performed on 66 children of 2-7 years of age who had been referred for first time, for nonbrain non-liver elective surgery (class 1 Anesthesia). This study was designed to define the efficacy of oral ketamine on Anxiety and Agitation and crying of children after separation from these parents, toleration of Anesthesia mask and IV needle. Sleeping before Anesthesia and entry into the operating room samples were divided in to two groups, cases and control. 5mg/kg of ketamine plus 0.2cc/kg of fruit juice was given to the case group while only 0.2cc/kg of fruit was given to the control group 30 minutes before the operation.
Results: Our results showed that 78.8% of children in the case group did not cry when they were separated from their parents and 78.8% of them did not show any resistance. 34.4% of children in the case group showed no response and 59.4% also had low response. Only 6.1% of children in the control group had no response while 78.8% of them had responses such as intense body movements and pulling of hand. 69.7% of the case group were cooperative when putting on the anesthesia mask while 75.8% of the control group refused to wear the mask, 81.8% of the children in the case group were asleep before Anesthesia while all of the children in the control group were awake and uneasy.
Conclusion: These findings indicate that ketamine can be used as a preanesthetic drug to decrease the anxiety and fear of children and to calm them before their transfer to the operating room.
Shima Chehreie, Parvin Rostami, Jhla Bezady,
Volume 6, Issue 4 (Winter 2003)
Abstract
Introduction: stress in the natural reflection of living creatures against internal and external motivations while stress hormones are secretion through cardiovascular, every production, and security systems. Some stress producing factors are muscular activities, anesthetics, surgery, starvation, water deprivation, etc. Thus, we studied effect of prenatal water deprivation stress on hormone level and sexual dimorphic nucleus in male rats.
Materials and methods: In an experimental design, adult female and male Wistar rats (180 gr) acquired from Pastor institute and were coupled. Pregnant rats were divided randomly into control and experimental groups. Both groups were maintained under a controlled temperature (20±2°C) and photoperiod (13:11h, light: dark) conditions. Controlled group had food and water available ad lib, but experimental group had access to food and were deprived of water from the beginning of third week of pregnancy to the end of week. At 42 days at birth, male rats were slight anesthetic in order to prepare the blood and morphometric evaluations.
Results: Plasma testosterone average level in experimental group was less than controlled groups (p<0.001), while in the comparison between experimental and controlled groups, progesterone indicates significant increment (p<0.001). There is no statistically significant regarding Estradiol level between both groups. Historical study indicated that the decreased size and number of neurons of MPO and Sch nuclei were significant in experimental compared to controlled ones.
Conclusion: Prenatal water deprivation through affecting MPO and Sch nuclei, approximate inhibition of nuclei and decrease in secretion of Testosterone cause the emergence unusual sexual behavior and similar female sexual behaviors in male experimental rats in the postnatal and maturity. |
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Shahram Baraz, Maryam Rostami, Fereshteh Farzianpor, Abdolrahman Rasekh,
Volume 12, Issue 2 (9-2009)
Abstract
Background: The most important determinant factor in elder’s quality of life is healthy. Since health can be declined by aging, in health promotion consider an effective model of care can be vey important. We surveyed the effect of Orem Self Care Model on quality of life (QOL) of elderly in Masjed Solaiman. Methods and Materials: This is a pre and post quasi-experimental study was carried out on 349 elderly clients which were selected from 11 health care centers in Masjed Solaiman in 2007-2008. Orem Self Care program was performed during a 3 months in days that the clients came to health care centers. Data were gathered by a short form questionnaire (SF36) before and after the intervention and was analyzed by descriptive statistics and paired t-test. Results: Results showed a significant increase in mean scores of different dominations of QOL including health, physical performance, physical role- performance, emotional role- performance, social performance, body pain, power and energy, general health perception, and overall mean of QOL. Paired t-test showed a significant difference (p<0.001) between all of dominations of the quality of life. Conclusion: Performing Orem Self Care educational program had a positive influence on improving QOL of elderly.
Javad Baharara, Kazem Parivar, Alireza Ashraf, Roya Rostami,
Volume 12, Issue 4 (2-2010)
Abstract
Background: Noticing the daily advancement of the role of electromagnetic field generators in human life, examination of the biologic impacts of these waves has come to be extensively appreciated by researchers. During pregnancy, vitamin A is extremely essential for the development of fetus and its lack, insufficiency or excess can result in embryonic malformations. This study investigated the synergetic effects of vitamin A and extremely low frequency electromagnetic fields on the development of embryo skin in Balb/C mice. Materials and Methods: This study was experimental in nature. Eighteen pregnant mice were divided into control, sham-exposed and experimental groups. The mice in the experimental group were given an intra-peritoneal injection of 15000 IU/kg vitamin A on the 10.5th day of gestation and were, then, exposed to a 50Hz electromagnetic field 4 hours a day from 10 through 12th day of gestation. The animals were dissected and investigated morphologically and histologically on 17.5th day of gestation. Results: The results showed an increase in the mean weight of fetuses in the experimental group in comparison to the sham- exposed group (p<0.05). Also, Crown-Rump of fetuses in the experimental group increased in comparison to those in the sham- exposed group (p<0.001). Epidermis thickness increased significantly in experimental group in comparison to sham- exposed (p<0.05), while the average number of basal, spinous cells and hair follicles decreased significantly in the experimental group compared to the sham- exposed (p<0.001). Conclusion: The findings indicate that vitamin A usage and synergetic exposure to low frequency electromagnetic fields (50Hz) profoundly affect the development and growth of skin epidermis in the fetus of Balb/C mouse.
Majid Moghadaszadeh, Ebrahim Fattahi, Mohamad Hosein Somi, Manochehr Khosh Baten, Toraj Rosta,
Volume 15, Issue 2 (June-July 2012)
Abstract
Background: H. pylori infection is common worldwide involving 50% of the general population. The aim of this study was to compare the effect of two sequential regimen therapies on the eradication of H. pylori. Materials and Methods: In this clinical trial, 150 patients were allocated to two groups of 75 each: group A and group B. The eradication of H. pylori in groups A and B was based on azithromycin and ofloxacin sequential regimens, respectively, and the results were compared between the groups. The data were analyzed by t-test, Chi-square test, and Fisher’s exact test using SPSS software version 16. Results: Mean of the patients’ age was 39.3± 1.2 within the age range of 18 to 85 years. There were not significant differences between the two groups considering the type of peptic ulcer. In group A, Urea Breath Test (UBT) was negative in 67 (89.3%) patients while in group B, it was only positive in 8 (10.7%) patients. In group B, there were 64 (85.3%) negative and 11 (14.7%) positive UBT test results. There were no significant differences in H. pylori eradication rates between the two groups (P=0.31). Conclusion: Noticing the absence of a significant difference between the two groups in terms of H. pylori eradication, it can be concluded that ofloxacin-based drug regimens have no superiority over azithromycine-based regimens and each regimen can be prescribed considering drug complication rates in different patients.
Hadi Ansarihadipour, Maryamsadat Alhoseini, Soheila Rostami , Narges Farahani, Mahya Hashemi ,
Volume 15, Issue 2 (June-July 2012)
Abstract
Background: The aim of this study is to assess antioxidative and pro-oxidative efficacy of ascorbate on serum albumin during iron-induced oxidative stress. Materials and Methods: In this experimental study, albumin was placed in the oxidative system containing iron ions and different concentrations of ascorbate. To monitor albumin degradation, sodium dodecyl sulfate polyacrylamide gel electrophoresis was performed according to Laemmli procedure. Oxidative modification of albumin was demonstrated using a method for determination of carbonyl groups by 2,4-dinitrophenylhydrazine. Results: By applying the carbonyl assay, ascorbate showed a dual effect: initial pro-oxidative effect on albumin changed to an antioxidant one in a dose-dependent manner. Our findings showed prooxidant effects for ascorbate in low concentrations (0-100 µM) and antioxidant effects in higher concentrations (100-300 µM). Also, electrophoretic pattern of plasma proteins showed significant protein aggregations in the range of 35 to 45 kDa of MW and protein degradations in the range of 115 to 180 kDa. Conclusion: Ascorbate can produce reactive oxygen species and can also inhibit the production of these oxidants in the presence of iron ions as well. These findings may be directly applicable to oxidative states during the administration of ascorbate and may be important in preventing oxidative modifications of proteins in blood circulation and other biological fluids.
Maral Rostami Chayjan, Marjan Sabbaghian, Mehdi Alikhani, Fazel Sahraneshin Samani , Reza Salman Yazdi , Seyed Navid Almadani, Anahita Mohseni Mehbodi,
Volume 17, Issue 5 (8-2014)
Abstract
Background: Human &beta-defensin 126 (12kDa) is a small cationic glycoprotein that is highly rich of cysteine. DEFB126 gene is located on the subtelomeric end of 20p1.3 in human. High expression of this protein is reported in epididymis. This polypeptide coats the plasma membrane of sperm during epididymal transit. It is likely that &beta -defensin 126 might have role in unexplained male infertility since it involves in sperm maturation and capacitation. The current research designed to investigate if there is relation between &beta-defensin 126 gene mutation and unexplained male infertility.
Materials and Methods: In this case-control study we followed a two cytosine nucleotides deletion of &beta-defensin 126 gene in 35 Iranian men with unexplained infertility and 40 fertile men with normal spermogeram as control group. Standard PCR, SSCP(Single strand conformational polymorphism), and sequencing were used to detect genetic alteration of &beta-defensin 126. ELISA was performed for the assessment of the protein expression on sperm cells.
Results: Analysis of genetic data revealed 28.6% homozygote deletion in unexplained infertile men while this deletion was detected in 7.5% of controls. The deletion frequency was statistically higher in infertile patients than normal control group (p<0.05). The protein expression was less in men with del/del genotype compare to the other genotypes (p<0.005).
Conclusion: Our study shows that this common sequence variation of &beta-defensin 126 takes part in impairment of male reproductive function. Consequently, men with the del/del genotype are significantly less fertile than men who carry the wild type allele.
Niloofar Dadashpour, Esmaeel Moshiri, Ali Reza Kamali, Ali Reza Rostami, Majid Golestani Eraghi,
Volume 18, Issue 3 (6-2015)
Abstract
Background: Atrial fibrillation (AF) is the most common complication after coronary artery bypass graft surgery (CABG). This complication causes an increase in morbidity and mortality after CABG and also increases the length of ICU stay and hospitalization. The aim of this study is to evaluate the prophylactic effect of amiodarone in reducing the incidence of post CABG atrial fibrillation.
Materials and Methods: In this clinical trial study, 204 patients, candidate for elective CABG, entered the study according to inclusion and exclusion criteria, and randomly divided into two equal groups. The case group received 300 mg of intravenous amiodarone before anesthesia induction and the control group received normal saline. Incidence of AF was recorded until 24 hours after CABG.
Results: The incidence of post CABG AF was 16 patients in the case group and 35 patients in the control group. Comparison of the frequency of AF between groups by Chi square analyses showed a significant difference (p=0.037) and the incidence of AF was significantly lower in the amiodarone group.
Conclusion: In total, amiodarone could significantly prevent the incidence of atrial fibrillation after coronary artery bypass surgery. In this study, patients took this medication only in the first 24 hours, while in some studies, this drug has been prescribed for even 14 days.
Ali Reza Rostami, Mehrzad Sharifi, Ali Reza Kamali, Masoomeh Kalantari,
Volume 18, Issue 10 (1-2016)
Abstract
Background: Post ischemic myocardial reperfusion can impair CABG outcomes and cause increased mortality, hospital stay and costs. Then, increased oxygen free radicals lead to lipid peroxidation and sulfhydryl group oxidation. The aim of this study is to evaluate whether N-acetylcysteine and Vitamin C as antioxidants could effect postoperative outcomes of on-pump CABG.
Materials and Methods: In this clinical trial, patients who had undergone CABG were studied in 4 groups receiving Vitamin C, N-acetylcysteine, Vitamin C & N-acetylcysteine and traditional drugs. The study population consisted of 50 patients in each group. Data were recorded in a checklist and analyzed by using SPSS 20.
Results: Mean pump time, ICU stay, hospital stay, the distribution of troponin positive serum, arrhythmia and need for reoperation were significantly different between groups. Gender distribution, mean cross-clamp time, serum creatinine level before and after surgery, the need for inotropic drugs and required dose level of it, showed no significant differences between groups.
Conclusion: It seems that the combination of N-acetylcysteine and Vitamin C had a stronger effect on the defference between the mean of pump time, hospital length stay and length of ICU stay versus the administration of N-acetylcysteine or Vitamin C alone.
Mahsa Rostamian Delavar, Masoud Baghi, Elahe Yadegari, Kamran Ghaedi ,
Volume 20, Issue 8 (11-2017)
Abstract
Abstract
Background: Oxidative Stress and mitochondrial dysfunction leading to apoptotic death of neurons play key role in the pathogenesis of the Parkinson's disease. On the other hand، misregulation of microRNAs can cause several neurodegenerative diseases. Sirt1 and Bcl2 as two key genes, regulate pathogenic processes in neurodegenerative diseases such as mitochondrial dyfunction, oxidative stress and apoptosis.
Materials and Methods: To investigate the role of microRNAs in model of Parkinson's disease, miRWalk 2.0 and TargetScan (v7) databases were served to predict microRNA-target interactions.
Results: Possible targeting effects of different microRNAs on Bcl2 and Sirt1 genes in Rat organism were analyzed. Merging data from databases has shown that rno-miR-449a, rno-miR-182, rno-miR-211, rno-miR-34b, rno-miR-34c, rno-miR-448, rno-miR-466b and rno-miR-96 with strong possibility can inhibit expression of Bcl2 gene. Also, rno-miR-181, rno-miR-211, rno-miR-27a, rno-miR-449a, rno-miR-34c, rno-miR-30, rno-miR-200a and rno-miR-448can inhibit Sirt1 gene with high possibility.
Conclusion: According to the findings, it can be predicted that regarding to high interaction scores of rno-miR-211, rno-miR-34c and rno-miR-448 and 449awith Bcl2 and Sirt1 genes in above-mentioned databases, these microRNAs probably can have critical role in disease process. Thus, these microRNAs can be introduced as appropriate candidates for investigations in in vitro model of Parkinson's disease.
Mehdi Rostamizadeh, Alireza Elmieh, Farhad Rahmani Nia,
Volume 22, Issue 1 (4-2019)
Abstract
Background and Aim: Physical activity causes the releases of bone resorption indices in the bloodstream by the mechanical load on bone, which in interaction with adipokines reduces obesity and prevent its complications. So, the present study aims to compare the effects of aerobic and resistance exercise on Anthropometric Indices and osteocalcin, leptin, adiponectin levels in overweight men.
Materials and Methods: A total of 40 overweight young healthy men (BMI 28.67±0.96 and age 31.50 ± 2.23) were randomly assigned to control (n = 14), aerobic exercise (n = 13) and resistance exercise (n = 13) groups. Subjects in the exercise group were on 8-week supervised exercise training programme for three sessions per week (aerobic exercise were performed at 60-85% of HRR, and resistance exercise were performed at 55-75% of 1RM). Osteocalcin and adipocytokines (leptin, adiponectin) were assessed from fasting blood samples before and after the 8-week exercise programme. Data were analyzed by t-test and ANOVA.
Ethical Considerations: This study with research ethics code IR.IAU.RASHT.REC.1396.124 has been approved by research ethics committee at Islamic Azad University, Rasht branch, Iran and also has been registered with code IRCT20180226038876N1 at Iranian Registry of Clinical Trials (IRCT).
Findings: Aerobic and resistance training led to decrease in anthropometric indices (p<0.05), leptin levels (p<0.001, p=0.001) and increase in osteocalcin (p=0.001, p<0.001) and adiponectin (p=0.001, p<0.001), respectively. In addition, the difference between the two training groups was not statistically significant (p>0.05).
Conclusion: Considering to the effects of aerobic and resistance exercise on osteocalcin and adipocytokines level, it seems that both exercise methods can be increasing mechanical load on bone mass and cause to change in energy metabolism and body weight and can be an important factor in decrease of obesity complications.
Ayatollah Fathi, Solmaz Sadeghi, Ali Akbar Maleki Rad, Hossein Rostami, Karim Abdolmohammadi,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: Anxiety is one of the clinical signs of viral diseases such as Coronavirus Disease 2019 (COVID-19), which can threaten the immune system. This study aims to investigate the effect of health-promoting lifestyle and psychological well-being on COVID-19-induced anxiety in non-medical students
Methods & Materials: This is an analytical/correlational study conducted on 307 non-medical students of Islamic Azad University in Tabriz, Iran, who were participated voluntarily in the study. They completed the Corona Disease Anxiety Scale developed by Alipour et al. (2019), Ryff’s Scales of Psychological Well-Being (SPWB), and Health-Promoting Lifestyle Profile (HPLP) developed by Walker et al. (1987). The collected data were analyzed in SPSS v. 20 software by using the stepwise regression analysis
Ethical Considerations: This research conducted based on the Ethical Committee of University of Tabriz (TABRIZU.REC.1399.018).
Results: Two SPWB components of “personal growth” and “positive relations with others” were able to predict the COVID-19-induced anxiety, which together explained 72% of anxiety variance in students. Moreover, two HPLP components of “spiritual growth” and “responsibility” could predict the COVID-19-induced anxiety and together explained 9% of the anxiety variance.
Conclusion: Promoting personal and spiritual growth, having positive relations with others, and responsibility can significantly reduce the anxiety induced by the COVID-19.
Fatemeh Rostamkhani, Mohammad Ghamari, Vahideh Babakhani, Effat Sadat Merghati Khoei,
Volume 25, Issue 3 (August & September 2022)
Abstract
Background and Aim Sexual function is an important part of menopausal women's lives, and changes in it, especially during menopause, can affect their health. The aim of this study was to compare the effectiveness of cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) on the sexual function of postmenopausal women.
Methods & Materials This research was a quasi-experimental with pre-test, post-test and follow-up design with control group. The statistical population of the study included postmenopausal women who referred to Zanjan Health Center in 2020 to receive services. Among them, 45 were selected using the available sampling method and were randomly assigned to three groups of 15, and control group using randomly assigned block allocation method. Therapeutic sessions were held in 8 sessions and each session was held for 2 hours. Data were collected by FSFI (Female Sexual Function Index) and were analyzed using ANOVA with repeated measures analysis via SPSS software, version 24.
Ethical Considerations This study was approved by the ethics committee of the Zanjan University of Medical Sciences (Code: IR.ZUMS.REC.1398.328).
Results In the post-test and follow-up phase, there was a significant difference between both CBT and ACT methods compared to the control group in sexual function respectively (P<0.05, F=17.857), (P<0.05, F=12.115). That is, treatment with CBT and ACT improved the sexual function of postmenopausal women, which had a lasting effect for three months, and there was no significant difference between the groups involved in sexual function (P>0.05, F=0.494).
Conclusion Cognitive-behavioral therapy and acceptance-based therapy have improved sexual function in postmenopausal women, so it is recommended that these therapies be used to improve the sexual function of postmenopausal women in health centers.
Dr Zahra Miraki, Dr Masomeh Rostamzadeh, Mr Aras Feizi, Dr Azad Shokri, Dr Mohammad Aziz Rasouli,
Volume 26, Issue 5 (December & January 2023)
Abstract
Introduction: The dentist's level of knowledge and abilities is one of the determining factors in the correct selection and application of dental cements. This study aimed to investigate the level of knowledge, attitude, and practice of general dentists and specialists about the application of different dental cements.
Methods: This descriptive-analytical study was cross-sectional one which conducted on 150 specialist and general dentists in governmental and private centers in Kurdistan province (2019) who performed fixed prosthetic treatments, was done through census and available sampling. The data collection tool was a questionnaire. To analyze data, T-test and ANOVA tests were used in SPSS-22 software. A significance level was considered less than 0.05. Ethical considerations: This study was conducted after the approval of the protocol in the research ethics committee and receiving the ethical code number IR.MUK.REC.1398.302 and according to the Declaration of Helsinki.
Results: The overall average score of dentists' knowledge was 6.5, which was close to and higher than the average scores and had a significant relationship with the grade and place of employment (P<0.05). The overall average score of attitude was 3.4, which was almost equal to the average scores. There was a significant relationship between grade and gender with attitude score (P<0.05). The overall average score of the dentists' practice was 5, which was higher than the average scores, and the practice score had a significant relationship with gender, place of employment, and grade (P<0.05).
Conclusions: The average score of knowledge, attitude, and practice of dentists was average, and in general, the scores of specialists were higher than general dentists. Women had a higher attitude and practice score. People working in the private sector had a higher knowledge score. To increase the knowledge, attitude, and practice of general dentists, there is a need to hold training courses.
