Journal of Arak University of Medical Sciences

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Showing 5 results for Rahimian

Effect of Allium Sativum extract on acid and pepsin secretion in basal condition and stimulated with Pentagastrin in rat

Mehrdad Shahrani, Fatemeh Nabavizade, Mahmoud Rafian, Hedayat Shirzad, Morteza Hashemzade, Hossein Yousefi, Reza Khadivi, Asadolah Amini, Bahman Khalili, Ghorbanali Rahimian,
Volume 10, Issue 3 (6-2007)

Abstract

Introduction: Allium Sativum (garlic) is used widely in the world, especially in Iran. This plant is used in cooking foods as an odorant. In Iran it is believed that it is useful for gastrointestinal disorders. So in this study the effect of Allium Sativum extract on acid and pepsin secretion in rat is investigated. Materials and Methods: This experimental study is performed on two groups of rats (12 in each group: control group and allium sativum group). After anesthesia with nesdonal (50 mg/kg, ip), rats had gone under surgical tracheotomy, laparatomy and gasterodeodenostomy. In garlic group Allium Sativum extract (100mg/kg) was introduced into the stomach by gasterodeodenostomy canula. In order to stimulation of acid and pepsin secretion, Pentagastrin was used (25mcg/kg, ip). Stomach secretion was washed out and acid was measured using titerimetery and pepsin using Anson method. Data was analyzed using t-test. Results: Allium Sativum caused a meaningful increase in acid and pepsin secretion in garlic group comparing to control group (p<0.001). Pentagastrin also increased acid and pepsin secretion in control group (p<0.001). Conclusion: Using garlic in nutritional regimen causes an increase in acid and pepsin secretion in those using this plant.

The Psychological, Demographical and Socio-Economic Factors Related with Suicidal Ideation among General Population of Semnan City in 1391

Eshagh Rahimian Boogar, Kaveh Alavi, Maryam Esfahani,
Volume 17, Issue 1 (4-2014)

Abstract

Background: Comprehending of suicidal ideation and related factors has valuable clinical outcomes in domains of prevention and crisis intervention. The aim of the present study was to explore the predictive role of psychological, demographical and socio-economic factors in suicidal ideation.

Material and Methods: In a cross-sectional descriptive study, 671 persons among general population of Semnan City were selected by voluntary sampling. Data were collected with NEO-Five Factor Personality Inventory, Symptom Check-List Revised, The Defense Style Questionnaire, The Beck Scale for suicide Ideation, The Beck Hopelessness Scale, The Social Support Questionnaire and demographical questionnaire, then analyzed by correlation and Logistic Regression with SPSS.

Results: Literacy level (OR=1.237 P<0.014), Family relationships (OR=1.873 P<0.010), Outcome (OR=4.211 P<0.003), Job status (OR=3.149 P<0.008), History of psychiatric disorders (OR=5.754 P<0.003), Hospitalization in psychiatric ward (OR=2.003 P<0.011), Neuroticism (OR=6.136 P<0.001), Extraversion (OR=3.612 P<0.005), Neurotic defense style (OR=2.468 P<0.005), Mature Defense Style (OR=4.107 P<0.002), Immature Defense Style (OR=3.059 P<0.003), Social Support (OR=7.609 P<0.001), and Hopelessness (OR=9.834 P<0.001) significantly differentiated persons with suicidal ideation from persons without suicidal ideation (P<0.001). These variables totally could correctly predict 97.4% of suicidal ideation.

Conclusion: In this model, risky psychological, demographical and socio-economic factors increase the odds ratio of suicidal ideation. These findings have importance for designing of preventive interventions and interventional programs for self-harm behaviors.

Effectiveness of a Mindfulness-Based Stress Reduction Program on Functional Disability of Patients with Multiple Sclerosis

Narges Ensan, Isaac Rahimian Boogar, Siavash Talepasand, Fariborz Estilaee,
Volume 22, Issue 5 (11-2019)

Abstract

Background and Aim Multiple Sclerosis (MS) is an unpredictable disease that can change individuals' lifestyle. The purpose of this study was to investigate the effect of a Mindfulness-Based Stress Reduction (MBSR) program on functional disability of patients with MS.
Methods & Materials The is an experimental study with pre-test/post-test/follow up design using control group. The study population consisted of all male and female patients with MS living in Neyshabur county, Iran. Of these, 47 were selected using a convenience sampling technique and randomly assigned into two groups of intervention (n=22) and control (n=25). The intervention group received MBSR therapy for 8 sessions, while the control group received no intervention. The follow-up was performed after one month. Subjects’ functional disability was measured by using the World Health Organization Disability Assessment questionnaire. The collected data were analyzed using SPSS v.21 software usingrepeated measurements Analysis of Variance (ANOVA).
Ethical Considerations This study obtained its ethical approval from the Research Ethics Committee of Neyshabur University of Medical Sciences (code: IR. NUMS.REC.1397.004)
Results The results of univariate ANOVA showed the significant effect of time and the interaction effect of time and group on functional disability of samples. The results of between-group ANOVA a significant difference between the intervention and control groups in functional disability (p <0.05). Pairwise comparison of the interaction effect of time and group showed a significant difference between the pre-test, post-test and follow-up scores (P = 0.001), but no significant difference was reported between the post-test and follow-up scores.
Conclusion The MBSR program could reduce the functional disability in patients with MS due to ease of treatment, faster patient education, and the short duration of intervention sessions.

Projective Response of Patients with Somatic Symptom Disorder Compared To Controls Based On Location Score in Rorschach Test

Zeinab Abdolhosseini, Isaac Rahimian Boogar, Siyavash Telepasand,
Volume 22, Issue 6 (February & March 2020)

Abstract

Background and Aim: Physical complaints that have no clear cause are a process that is commonly seen in patients with Somatic Symptom Disorder (SSD). The increasing number of patients with this disorder and its related chronic symptoms including changes in quality of life and loss of individual efficiency has created social and psychological economic costs for these patients and their families.
Methods & Materials: This descriptive cross-sectional study conducted on 70 patients with SSD having digestive symptoms and chronic pain referred to the health centers in Semnan, Iran in winter 2018. They were selected using a convenience sampling method. The data collection tools were 15-item Patient Health Questionnaire Physical Symptoms (PHQ-15) and Rorschach test (Exner’s Comprehensive System). In order to analyze the collected data, multiple linear regression analysis, logistic regression analysis, and multivariate ANOVA were performed in SPSS v. 22 software.
Ethical Considerations: The present study was approved by the Research Ethics Committee of Semnan University of Medical Sciences (code: IR.SEMUMS.REC.1397.029).
Results: Perceived location indices including D and Dd scores in Rorschach test were able to significantly differentiate the SSD patients from controls (P<0.05). In the logistic regression model, 70% of participants were classified properly.
Conclusion: There is difference in projective responses between SSD patients and controls, and patients were less holistic. Anxiety and psychiatric symptoms were also higher in patients with SSD.

The Prediction of Somatic Symptom Disorder Based on Demographic Characteristics, Social Isolation, and Perceived Anxiety

Ahmad Ansarifar, Isaac Rahimian-Boogar, Siavash Talepasand,
Volume 27, Issue 6 (1-2025)

Abstract

Introduction: Sociodemographic factors and perceived anxiety have a significant impact on the development of somatic symptom disorder. This study aimed to investigate the role of demographic characteristics, social isolation, and perceived anxiety in predicting somatic symptom disorder.
Methods: In a cross-sectional descriptive study among adults aged 18 to 60 in Tehran in 2023, 437 participants were selected based on convenience sampling. The participants completed the Somatic Symptom Disorder Questionnaire (SSEQ), Social Isolation Questionnaire, and Perceived Anxiety Questionnaire. Data were analyzed using Pearson’s correlation and multiple regression analysis.
Results: The results indicated that social isolation and perceived anxiety have a positive and significant correlation with somatic symptoms disorder (P < 0.01). There was no correlation between demographic characteristics (age, gender, marital status, education, and employment status) and somatic symptoms (P <0.01). Multiple correlation and regression coefficients among research variables were statistically significant (P < 0.01).
Conclusions: The examined model was almost able to predict 22% of the somatic symptoms of the disorder. The results have implications for formulating interventions based on social isolation and perceived anxiety in controlling somatic symptoms. It is essential to pay attention to social isolation and perceived anxiety in the formulation and implementation of interventions and educational programs for the prevention and improvement of somatic symptom disorder.

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