Showing 9 results for Panahi
Touba Kazemi, Hossain Panahi Shahri, Maryam Hossaini Farash, Mahdi Darabi, Mohsen Kashanian, Hossain Akbari,
Volume 8, Issue 3 (1-2006)
Abstract
Introduction: Hyperlipidemia is one of the main known risk factors for coronary artery disease. Regarding the undesirable consequences of hyperlipidemia and its long-term treatment, it is important to use drugs with lesser complications during the long period of treatment.
Materials and Methods: This study was a double-blind randomized clinical trail that carried out on 65 patients with hyperlipidemia. Patients were divided into two groups. Case groups took dill pearl, and control group took placebo pearl for one month. Serum lipids of both groups were measured before and one month after interference. Data was analysed with t-test and p<0.05 was considered significant.
Results: In this study , differences between mean level of cholesterol, triglyseride, HDL and LDL in case group before and after interference were statistically significant (P<0/05) but in control group only difference between HDL before and after interference was significant .
Conclusion: Regarding the result of the study dill pearl can be a useful drug for treatment of hyperlipidemia.
Afsaneh Karami, Ahmadreza Mobaien, Manizheh Jozpanahi, Masomeh Sarokhani,
Volume 14, Issue 7 (Brucellosis Supplement 2012)
Abstract
Background: Brucellosis is an endemic disease in Iran and its treatment is a medical problem. This study was performed to observe the influence of the administration of corticosteroid on symptomatology of subjects with acute, subacute, and chronic brucellosis.
Materials and Methods: In this randomized controlled trial, 48 patients with brucellosis were randomly assigned to two groups. The first group (N=30) received the standard regimen plus dexamethasone (4 mg t.d.s for 5 days) and the second group (N=17) received only the standard regimen. The results of corticosteroid administration were evaluated according to such factors as clinical status of the patient, duration of hospital stay, duration of illness, pain score, and use of analgesics. The results were analyzed by Chi-square test, Fisher’s exact test, independent sample t-test, and Mann-Whitney test.
Results: No significant differences were seen in the mean of hospital stay, duration of illness, and use of oral and injectable analgesics between the two groups (P<0.05). Also, there was not a significant difference in mean pain score reduction between groups 1 and 2 (P<0.05).
Conclusion: Noticing the findings of this study, corticosteroid does not seem to alter the clinical course of brucellosis significantly. Nevertheless, further controlled clinical trials with larger sample sizes are recommended
Manizheh Jozpanahi , Afsaneh Karami, Firoozeh Salimi ,
Volume 16, Issue 11 (2-2014)
Abstract
Background: The Infections that are related to vascular access, are regarded as Important factor in mortality and morbidity in the patients with immune deficiency including hemodialysis patients. Staphylococcus aureus is the most common and most Important organism involved in this regard and it cause bacteremia and its complications in the patients is important. This organism can cause carriage states and its most frequent carriage source is in the nose. The aim of this study is determination of staphylococcal carriage states in the Zanjan hemodialysis patients and control group.
Materials and Methods: This cross sectional study is designed in the patients with chronic renal disease who were referred to the hemodialysis wards. Nasal samples were collected with sterile swabs. Then they were inoculated in the blood agar culture media and incubated at (35-37) degree for (24-48) hours. This method was taken for control group too. The collected data were analyzed with SPSS and Chi-Square statistically methods.
Results: Based on this study, 7.4 percent of patients and 11.1 percent of the control group were nasal carriers of staphylococcus aureus. The results did not show any meaningful statistically difference between the cases and control groups. But a meaningful statistically difference was observed in the Staphylococcus hemolyticus carriages and the nasal carriage of this organism was more common in the women of case group.
Conclusion: Based on our study, we don't find high prevalence rate of nasal staphylococcus aureus carriage among our case group, and It seems this organism isnot an important agent in our hemodialysis wards.
Maryam Panahi, Syamak Rakei Isfahani, Mahmoud Amini, Bahman Sadeghi Sadeh,
Volume 18, Issue 9 (12-2015)
Abstract
Background: Despite advances in surgical techniques and risk management practices in recent years, wound dehiscence following abdominal laparotomy has still high prevalence. The purpose of this study is to evaluate the effect of retention sutures on wound dehiscence of emergent abdominal laparotomy.
Materials and Methods: In this randomized clinical trial study, 160 patients scheduled for emergency laparotomy for peritonitis or trauma were enrolled. Half of the patients randomly underwent retention suture and the other half underwent routine sutures. Finally, the amount of surgical wound dehiscence and complications were assessed.
Results: Three patients (3.7%) in retention group and 11 patients (13.7%) in the control group developed wound dehiscence which there was a significant difference between them (p=0.025). It was determined by multivariate logistic regression that wound dehiscence is correlated with hemodynamic status, type of trauma and injury to the abdominal organs, and sex. The incidence of wound dehiscence, early hemodynamic instability, penetrating abdominal trauma and damage to the intestines were higher in males.
Conclusion: In general, it seems that the preventive use of retention sutures in patients with multiple risk factors for postoperative wound dehiscence can be useful.
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Yousef Panahi, Ehsan Sabori, Ali Rasouli, Goodarz Sadeghi Hashjin, Shiva Roshan Milani, Leila Derafshpour,
Volume 20, Issue 1 (4-2017)
Abstract
Abstract
Background: The aim of this study was to evaluate the effects of different concentrations of morphine and naloxone on epileptic activity in live brain slices taken from morphine-dependent and control infant mice.
Materials and Methods: Forty neonatal mice were randomly selected. To establish dependency, 2, 4, 8, 16 and 32 mg / kg morphine was injected subcutaneously once daily (0.1 cc) for 5 consecutive days from day 14-18 after birth. On postnatal days 19-20, brain slices were prepared and cerebrospinal fluid was perfused with low magnesium to induce experimental- epiletform activity. The effects of 10, 100 and 1000 µM concentrations of morphine and 10 µM naloxone were investigated on epileptic activity. Chenges in the number as well as onset and amplitude of activities were considered as an indicator to determine the quantity of their effect.
Results: The results showed that morphine 100 µM increased the activity while 10 and 1000 µM concentrations of morphine and 10 µM naloxone attenuated epileptic activity in both groups. Naloxone reduced pro-seizure effect of morphine, but anti-seizure effect of morphine couldn't restored by naloxone.
Conclusion: Morphine has a two-phase concentration-dependent effect on epileptic activity in the infant mice; so that low and high concentrations of morphine inhibit epileptic activity, but its moderate concentration potentiates the epileptic activity. Naloxone has an anti-seizure effect.
Mahdi Panahian, Ehsan Nafari, Nasim Daneshdoost, Danial Habibi,
Volume 20, Issue 10 (1-2018)
Abstract
Abstract
Background: Tympanometry is one of the most important audiological tests for the assessment of neonatal hearing screening programs. This test is usually done using a 226 Hertz probe tone; however, in infants less than 6 months of age, using this probe tone frequency is not reliable due to the different characteristics of the middle ear compared to adults. The purpose of this study was to assess the obtained tympanometric data in neonates 1 to 14 days with normal hearing using 226, 678, 800 and 1000 Hertz frequency probes tones.
Materials and Methods: In this cross-sectional study, 30 neonates aged 1 to 14 days who were diagnosed as normal in hearing aspect with using otoacoustic emissions test, were assessed by tympanometry. Tympanometric tests were performed using 226, 678, 800 and 1000 Hertz frequency probe tones for both ears. For data analysis, the T-paired method has been used.
Results: With using 226 Hertz frequency probe tone, incidence of unusual double peak tympanograms was observed in 65% of cases, which with increasing frequency of the probe tone, this percentage was decreased. There was also a statistically significant difference between the static admittance peak compensated in two 226 and 1000 Hertz frequency probes tones.
Conclusion: In neonates with normal hearing and without any risk factors for hearing loss, the 1000-Hertz Tympanogram shows a better middle ear status than the 226-Hertz tympanogram.
Seyyed Payam Shariatpanahi, Danial Habibi, Mohammad Rafiei, Yazdan Ghandi, Mehdi Anvari,
Volume 20, Issue 12 (3-2018)
Abstract
Abstract
Background: Today, the high prevalence of diabetes and its complications are one of the most important public health issues worldwide. For this reason, finding relations between diabetes risk factors is very effective in preventing and reducing complications. For discovering these relations, the data mining methods can be used. By extracting association rules, which is one of the data mining techniques, we can discover the relations between a large numbers of variables in a disease.
Materials and Methods: The population of this study was 1046 patients with type 2 diabetes, whose data had recorded between 2011 and 2014 at the Special Clinic for Diabetes in Tehran's Imam Khomeini Hospital. After pre-processing step with SPSS19 software, 573 people entered the analysis phase. The FP-Growth algorithm was applied to the data set to discover the relations between heart attack and other risk factors using Rapid miner5 software. Relations, after extraction, were given to the doctor to confirm clinical validation.
Results: The obtained results of studying these 573 people (Including 292 (51%) women and 281 (49%) men, with age range 27 to 82 years) showed that the lack of blood pressure, creatinine and diastolic blood pressure at its normal level, despite higher systolic blood pressure level than normal, doesn't increase the probability of heart attack.
Conclusion: Using association rules is a good way of identifying relations between the risk factors of a disease. Also, it can provide new hypotheses to do epidemiological studies for researchers.
Yousef Panahi, Davood Kiani Fard, Fatemeh Feyzi,
Volume 22, Issue 6 (February & March 2020)
Abstract
Background and Aim: The purpose of this study was to investigate the stimulatory and protective effects of Methylphenidate (MPD) on the experimental epilepsy induced by intraperitoneal injection of Pentylenetetrazole (PTZ) in adult male rats.
Methods & Materials: In this study, 15 male rats (weight, 200-250 gr) dividied into one control group (n=5) received normal saline and two treatment groups; the first group (n=5) received MPD with a dose of 2.5 mg/kg and the second group (n=5) received MPD with a dose of 5 mg/kg by gavage. After anesthesia with ketamine-xylazin combination and animal skull surgery, the recorded electrodes were inserted into the cranium in the stratum striatum layer of the CA1 region of the hippocampus, and epileptic activity was induced by intraperitoneal injection of PTZ (80 mg/kg) and the epileptiform activity was evaluated in terms of the number of spikes per time unit and their amplitudes by eTrace software.
Ethical Considerations: This study with an ethics code of FVMT.REC.1397.67 was approved by the Research Ethics Committee of the Faculty of Veterinary Medicine at University of Tabriz.
Results: Oral MPD at 2.5 and 5 mg/kg doses increased the number of spikes up to 576 and 613, respectively, compared to the control group (330 spikes), which were statistically significant. Amplitude of PTZ-induced epileptic activity after treatment with 2.5 and 5 mg/kg MPD reached 1254 and 1085 respectively compared to control group (1051), which were not statistically significant.
Conclusion: The doses of oral MPD used in this study potentiate seizure activity. Therefore, the use of this drug in people with a background of seizure or suffering from some types of seizure should be cautious, and the evaluation of its effect in these patients need further studies.
Mr Mahdi Panahian,
Volume 26, Issue 2 (June & July 2023)
Abstract
Introduction: Vestibular defects, vertigo and Dizziness may lead to delay in postural control, lack of coordination, vertigo attacks and ultimately imbalance in children. In this systematic review, the factors affecting children's balance disorders and the effective tests for evaluating these children were investigated.
Methods: Valid articles were searched in Pubmed, Google Scholar, Elsevier databases between 2000 and 2023 using the keywords Balance, Vertigo, Dizziness, Vestibular, Children. In the present study, research articles, narrative reviews, systematic reviews, and meta-analysis related to the purpose of the study were evaluated and included in the study.
Results: In the present study, a total of 95 articles were found. By repetition, 13 articles were removed and 82 articles remained in the study. By examining the titles of these articles, 7 articles were removed because the title was not relevant to the purpose of this study and 9 articles were removed because the full text of the article was not relevant,then leaving 66 relevant articles. 8 studies were excluded from the present study due to exclusion criteria. Therefore, a total of 58 articles were included in this systematic review and effective factors in the occurrence of balance disorders and effective assessment in identifying these disorders were found.
Conclusions: Correct diagnosis of balance disorders in children using appropriate tests not only prevents unnecessary examinations and reduces parents' worries, but is also a prerequisite for successful treatment.
