Journal of Arak University of Medical Sciences

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The effects of alcoholic leaf extract Ocimum basilicum on angiogenesis in chick chorioallantoic membrane

Fateme Niazi , Maryam Tehranipour, Khadije Shahrokhabadi,
Volume 19, Issue 7 (10-2016)

Abstract

Background: Angiogenesis is an important biological processes of new blood vessels in many pathological stages of development and embryo development occurs and a complex and dynamic phenomenon that is needed for development and other physiological processes. This study aimed to investigate the effect of alcoholic Ocimum basilicum leaf extract on angiogenesis chick chorioallantoic membrane is done.

Materials and Methods: In this experimental study 40 Ross fertilized eggs were randomly divided into four groups: control, sham-exposed and experimental groups were divided. The second day of incubation the eggs window was opened. Eighth day of the alcoholic extract of basil doses of 50 and 150 mg/kg on chick chorioallantoic membrane was injected. On day 12, embryos length and weight and chorioallantoic membrane (CAM) was photographed by photostereomicroscope Then the numbers and lengths of vessels in special area on CAM were measured with Image J. analyzed through by t-test and ANOVA (P<0.05).

Results: The data does not show significant difference between embryos length and weight in sham compare to all experimental groups. In the study vessels number just with 150 mg/kg observed significant.

Conclusion: Alcoholic extract of basil is an increase in the number of vessels and in this sense the healing and growth processes associated with them as well as effective.

Comparison of Sleep Quality in Pregnant Women With Preeclampsia and Control: A Case-Control Study

Azin Niazi, Maryam Moradi, Ehsan Mazloumi,
Volume 25, Issue 3 (August & September 2022)

Abstract

Background and Aim Preeclampsia is a common complication of the second half of pregnancy. Sleep disorders can cause high blood pressure by causing oxidative stress and endothelial dysfunction. Therefore, the present study was performed to determine the relationship between sleep disorders and preeclampsia.
Methods & Materials This is a case-control study that was performed on 240 women referred to the affiliated university hospitals in Mashhad. Sampling was performed in the case group of hospitalized women with a definite diagnosis of preeclampsia (n=90) and in the control group (n=150) among pregnant women without preeclampsia referred to the obstetrics clinic. Data collection tools included demographic information questionnaire and gynecological/obstetric records, Pittsburgh Sleep Quality Questionnaire and clinical evaluation form to determine the symptoms and severity of preeclampsia. Data analysis was performed using SPSS statistical software (version 22) and Mann-Whitney, Chi-square and Fisher tests. A P value of less than 0.05 was considered significant.
Ethical Considerations The present paper is the result of a research project approved by the Vice-Chancellor for Research of Mashhad University of Medical Sciences (Code: IR.MUMS.NURSE.REC.1397.042).
Results The mean amount of real sleep at night in the group of healthy individuals (8.4±2.3) was significantly higher than patients (8.0±‌2.2) (P‌=‌0.028). In terms of loud snoring, waking up in the middle of the night was most frequent in the affected group (P‌<0.001). There was a statistically significant difference between the two groups in terms of sleep quality score level (P‌<0.001) based on logistic regression test in women with severe sleep problems at risk of preeclampsia (P‌<0.001, 95% CI 2.9-42.2, OR‌: 11‌/‌11) (11/11) was equal compared to healthy women.
Conclusion The present study showed that sleep disorders in pregnancy are associated with an increased risk of preeclampsia.

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