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Showing 5 results for Nazemi

Ali Nazemi, Mahdieh Sadat Ghafari, Mohsen Dalvandi,
Volume 19, Issue 1 (4-2016)
Abstract

Background: Myelomeningocele is one of the common congenital malformation in childhood that has association with many disorders. in addition to routine management of associated disorders surgical repair of myelomeningocele has been considered in many cases . The aim of this study is to evaluate the role of myelomeningocele surgical repair in prognosis of children with myelomeningocele

Materials and Methods: This is a case-control study from 2001 to 2013 in 60 infants with myelomeningocele in two department of neurosurgery in Arak and Ilam cities (Vali Asr and Imam Khomeni hospitals, respectively). Infants were divided into two groups according to operable and inoperable cases (each group includes 30 cases). The prognosis of two groups was investigated with respect to mortality, and Stark and Drummond disability rating scale. Data were analyzed with SPSS 18 software.

Results: Case group had better prognoses compared to control with respect to handicap (p=0.003), urinary tract disorders (p=0.006), IQ (p=0.001), global disability(p=0.006) and mortality rate, but there was no difference between two groups with respect to hydrocephalus(p=0.3).

Conclusion: According to the results, mortality, disability and prognosis of infants with myelomeningocele that underwent operation were better. In conclusion, early myelomeningocele repair is advised for infants, because it affects the improvement of prognosis and the quality of patients' life.


Morteza Gharibi, Simin Najafgholian, Fatemeh Rafiee, Ali Nazemi, Esmaeil Mansourizadeh,
Volume 22, Issue 5 (11-2019)
Abstract

Background and Aim American College Of Emergency Medicine (ACEM) guideline has a recommendation for early diagnosis of head injuries following mild trauma. In this study we examined the prediction power, sensitivity, and specificity of this clinical guideline in the need for computed tomography (CT) scan 
Methods & Materials This cross-sectional study was performed for 6 months on patients over 18 years old referred to the emergency department of Vali-e-Asr Hospital in Arak who met ACEM criteria for head CT scan for suspected mild trauma. Demographic characteristics, clinical symptoms, trauma mechanism, physical injuries caused by head trauma, and history of drug abuse were recorded. The consciousness level (Glasgow Coma Scale) was checked every two hours. Patients underwent treatment if there was a pathology in CT images, and those with no clear pathology were discharged after 6 hours and, followed up by phone for two weeks, and in case of any abnormality in the level of consciousness, they were re-examined by CT scanning.
Ethical Considerations This study has an ethical approval obtained from Arak University of Medical sciences (code: IR.ARAKMU.REC.1396.227).
Results 500 patients, 335 male (67%) and 165 females (33%) with the mean age of 46.39± 2.01 years were studied; the sensitivity the ACEM guideline for predicting the need for CT scan in patients with mild head trauma were 100% with a specificity of 3.46% (for the second recommendation, the sensitivity was 100% with a specificity of 6.7%) which indicated that the test was highly sensitive to diagnosing the patients, but its specificity was low.
Conclusion The ACEM guideline had high sensitivity to predicting the need for CT in patients with mild head trauma, but had very low specificity which makes it an unacceptable criterion for rejecting or performing CT scan in these patients.

Pedram Pouryari Biyachal, Najmeh Ranji, Ali Nazemi,
Volume 24, Issue 1 (April & May 2021)
Abstract

Background and Aim: Non-syndromic hearing loss is a genetically heterogeneous disorder. Mutation in the GJB2 gene is a major cause of non-syndromic hearing loss in numerous countries. This study aimed to evaluate GJB2 mutations in 31 individuals with non-syndromic hearing loss
Methods & Materials: In this descriptive cross-sectional study, the required blood samples were collected from 31 individuals with non-syndromic hearing loss in Rasht and Bandar Anzali Cities, Gilan Province, Iran. After DNA isolation, the GJB2 gene was amplified by the PCR method and underwent sequencing. 
Ethical Considerations:This study was approved by the Ethics Committee of the Islamic Azad University, Mashhad Branch (Code: IR.IAU.MSHD.REC.1398.027).
Results: In this study, 3 mutations were determined in 18 individuals with hearing loss. Accordingly, 35delG mutation had the highest frequency (48.38%) in individuals with hearing loss as homozygote (n=14) and heterozygote (n=2). A patient with heterozygosity in V153I mutation and a patient with compound heterozygosity in 35delG/G200R mutation was determined.
Conclusion: It appears that 35delG mutation is a common mutation in the GJB2 gene in individuals with non-syndromic hearing loss in Guilan Province.
Azam Nazemi-Harandi, Shadi Jazayeri, Haeideh Saberi,
Volume 25, Issue 1 (April & May- 2022)
Abstract

Background and Aim In modern life, emotional and social problems have taken the highest rank among mental illnesses. The present study aimed to provide a causal model for predicting children’s psychosocial problems based on parenting styles with an emphasis on the mediating role of social support.
Methods & Materials The present research was a cross-sectional analytic study. The study population included parents of children (under 5 years old with behavioral-emotional problems) referred to the comprehensive health centers services in Pardis City, Iran, in 2020. Of whom, 230 people were selected by convenience sampling method. Measurement tools included parenting styles, social support, and socioemotional problems questionnaires. Structural equation modeling with SmartPLS software was used to analyze the data. 
Ethical Considerations This study was approved by the Ethics Committee of Science and Research Branch, Islamic Azad University (Code: 99527).
Results The Mean±SD age of mothers was 32.87±7.87 years. Also, 60% of children were boys, and 40% were girls, with an Mean±SD age of 4.12±0.78 years. The Mean±SD scores of socioemotional problems, parenting styles, and social support were found to be 40.16±4.73, 152.23±18.10, and 34.66±6.49, respectively. The results of structural equation modeling showed that parenting styles had a significant role in predicting children’s socioemotional problems through social support mediation (P<0.05). Also, the fitting branches of the model showed the proper fit of the model through the composite reliability and the Cronbach alpha calculation. 
Conclusion The results of the present study emphasize the critical role of early childhood life and the need to focus on support facilities for mother-child couples at this age. Accordingly, providing psychological and supportive interventions for mothers with high stress can result in parental adjustment and mental health and, subsequently, the child’s normal development.

Azam Nazemi Harandi, Shadi Jazayeri, Haeideh Saberi,
Volume 25, Issue 2 (June & July 2022)
Abstract

Background and Aim Emotional/social problems in childhood are associated with delinquency in adolescence, violence in adulthood, and anxiety disorders. This study aims to investigate the role of parents’ stress and perceived social support in predicting children’s emotional/social problems.
Methods & Materials This is a descriptive-correlational study. The study population includes all parents and their children referred to health centers in Pardis, Tehran, Iran in 2020 who had children under 5 years of age. Of these, 230 parents were selected by a convenience sampling method. Data collection tools were the Parental Stress index, the multidimensional scale of perceived social support and the child behaviour questionnaire-parent form. For data analysis, multiple regression analysis was used in SPSS software, version 25.
Results Among participants, 42.6% were employed and 57.4% were housekeeper. The mean age of participants was 28.42±12.5 years. The results showed that parents’ stress and perceived social support had a significant role in predicting children’s emotional/social problems such that they explained 44.7% and 8.9% of the variance in children’s emotional/social problems.
Conclusion Parents’ stress and support from friends can be effective in predicting emotional/social problems of their children.


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