Showing 11 results for Nasiri
Amir Ashkan Nasiripour, Rahmatallah Jadidi,
Volume 11, Issue 1 (3-2008)
Abstract
Introduction: Optimum management of medical equipment in hospital settings has tremendous effects on decreasing costs and providing desired health and treatment services. This research has been undertaken to design a medical equipment management model for public hospitals of Iran. Materials and Methods: In this adaptive research, medical equipment management among United States of America, United Kingdom, Germany, Canada, Australia, Sweden and Italy, which have successful experiences and determined patterns for medical equipment management, are assessed with respect to 6 dimensions as structure, purchase, control, maintenance, training and distribution and according to the shared strategies in the mentioned countries, a model was designed for Iran's public hospitals. This model was validated using expert's survey in DELFI method. Results: In all of the studied countries, the medical equipment engineering unit is established for effective management of medical equipments and in direction with the main purpose of ensuring safety and improving patient care, clinical engineers are being trained. Trainings are designed according to international federation course plan for clinical engineers “which are combination of necessary engineering and managing courses for activities of hospital medical equipment management”. Under study issues include: precise need assessment for medical devices, balancing, use of life span expenditure, stock management, location finding, and needed physical space prediction, selection and purchase committee establishment, entering controls plus reception test, performance and safety control, activities documentation, using computerized systems for preventive maintenance and semi-centered distribution, are among necessary processes in the medical equipment management cycle of under studied countries' hospitals. Conclusion: Management and medical equipment engineering unit establishment in hospitals, selection and purchase committee formation, continuous equipment performance control during calibration process, equipment preventive maintenance according to workforce training schedule, training needed experts, and with respect to the topics of international federation courses for clinical engineering training in universities, will improve medical equipment efficiency in hospitals.
Amit Ashkan Nasiri Pour, Jamalodin Tabibi, Amin Ghasem Begloo, Rahmatolah Jadidi,
Volume 12, Issue 1 (5-2009)
Abstract
Background: Hospitals need performance evaluation systems for development and competition in order to evaluate the effectiveness and efficiency of their plans, processes and human resources. The objective of this research is to design an evaluation system at hospitals through the use of the Balanced Scorecard. Methods and Materials: In this comparative study, the selected countries consisted of Australia, USA, Canada and New Zealand, and 34 public hospitals of Iran which were applying strategic planning. Performance evaluations were examined in terms of 6 aspects including mission, vision, strategies, perspectives, objectives and measures .A pattern was designed for performance evaluation of public hospitals in Iran and was validated using experts’ survey of DELFI method. Results: All countries had mission and vision as important aspects of their performance evaluation model while health effectiveness promotion was the most important strategy. High quality health services, resource development, innovation and guaranty in continuous services were other strategies. Perspectives of Balanced Scorecard included customer, internal processes, learning and development of staff and financial affairs. All of the countries had objectives and measures for each of the perspectives. Iranian hospitals had mission, vision, strategies and objectives but for them perspectives had not been defined and measures were not congruent with strategies and objectives. In the model, 4 perspectives were determined to describe hospital strategies and to use competition benefits as well. Conclusion: Applying measures of 4 perspectives including "Patients and Community", "Internal process and Productivity", "Growth and innovation" and "financial aspects" to doevaluation of Iranian public hospitals collates their performance, improves productivity of their resources and enhances patients and community satisfaction.
Peyman Abdollahzadeh, Reza Shapouri, Shahrzad Nasiri Semnani, Hamed Alizadeh,
Volume 14, Issue 7 (Brucellosis Supplement 2012)
Abstract
Background: Brucellosis is caused by brucella which is a facultative intracellular pathogen invading both professional and nonprofessional phagosytic cells. Eucalyptus globulus is one of the most widely used medicinal plants in folk medicine throughout the world. The aim of this study was to evaluate the antibacterial effects of Eucalyptus globulus extracts on intramacrophage Brucella melitensis 16M.
Materials and Methods: In this experimental study, after preparing aquatic, ethanolic, and acetonic extracts of Eucalyptus globules, the effect of the extracts on intramacrophge survival of B. melitensis 16M obtained from cell culture of Balb/c mice peritoneal macrophages was studied. In order to do this, after lysis of macrophages, through preparation of serial dilutions and culture on Mueller Hinton agar medium, the number of colonies grown was counted.
Results: The maximum antimicrobial activity of Eucalyptus globulus extracts on intramacrophage B. melitensis 16 M were in 1:40 dilution (21.62 mg/ml) of the aquatic extract, 1: 640 dilution (1.26 mg/ml) of the ethanolic extract, and 1:320 dilution (2.59 mg/ml) of the acetonic extract after 24h.
Conclusion: Aquatic, acetonic, and ethanolic extracts of Eucalyptus globulus possess antimicrobial properties against intramacrophage B. melitensis 16M and ethanolic extract has the most effective antimicrobial activity on intramacrophage Brucella melitensis therefore, these extracts can be useful in treatment of brucellosis.
Somaye Ghaderi, Fatemeh Alaee Karahrudi , Parsa Yousefi Chaijan , Navideh Nasiri Oscui ,
Volume 16, Issue 10 (1-2014)
Abstract
Background: Hospitalization of a child in pediatric intensive care unit (PICU) is a very stressful experience for parents. High stress in father can product decline in psychological adaptation and associated problems. The present study aimed to determine effect of fathersʼ participation in the care of hospitalized child in PICU on fathersʼ stress and coping strategies.
Materials and Methods: This is a clinical trial with 60 fathers with children admitted to the PICU in intervention and control groups. Fathers in intervention group, participated in the care of the child in 5 times, during a 5-days course. Fathersʼ stress and coping strategies were surveyed in intervention group before and after participation course and in control group before and after a 5-days course.
Results: Fathersʼ stress in intervention group decreased significantly after participation (p˂0.001) but in control group difference was not significant after time course. Fathers in both groups applied similar coping strategies that majority were emotion focused.
Conclusion: Fathers having children in PICU would experience a lot of stress. Their participation in the care of the children would be very effective to decline their stress and reach most adaptation with disease, cure and cares in children.
Kobra Jahangirizade, Mahboobeh Nasiri, Naeimehossadat Asmarian,
Volume 19, Issue 1 (4-2016)
Abstract
Background: Recurrent pregnancy loss (RPL) is a heterogeneous condition with the prevalence of more than 1% among women of reproductive age, which is defined as the occurrence of more than two miscarriages. Immune-mediators, cytokines, determine the role of immune cells in response to tissue incompatibility conditions. Colony stimulating factor 3 (CSF3) is a cytokine affecting the expression of other cytokines such as IL-4, and suppressing the immune response against semi-allograft embryo. This study was done for the first time on the association of the rs1042658 polymorphism at 3’UTR of the CSF3 gene with the susceptibility to recurrent pregnancy loss, supposing the effect of it on the expression level and stability of the CSF3 gene transcript.
Materials and Methods: 122 RPL women and 140 healthy fertile women as a control group were enrolled in this case-control study. Genotype distribution of the selected polymorphism was evaluated by T-ARMS PCR method and the results were analyzed by logistic regression test.
Results: comparison of the genotypic frequencies in the 3'UTR of the CSF3 gene in patients and controls resulted in the statistically significant difference in the incidence of pregnancy loss in order to the protection effect of the genotypes carrying T allele was observed between two groups (p<0.05). History of the abortion among the relatives of RPL women versus the relatives of controls showed significant differences (p=0.05).
Conclusion: Findings showed significant relationship between rs1042658 polymorphism and the risk of recurrent pregnancy loss, which can affect the susceptibility of the condition.
Shekoofeh Rahimi, Mahboobeh Nasiri, Saeideh Arian Nia, Reza Farrokh Seresht,
Volume 19, Issue 9 (12-2016)
Abstract
Abstract
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with broad clinical manifestations, but unclear etiology. Extensive tissue damage occurs due to the production of auto-antibody against nuclear and cytoplasmic antigens. Regarding the involvement of GADD45A gene in cell cycle control, T-cell proliferation suppression, and genome epigenetic regulation, this case-control study was done for the first time to evaluate the association of rs581000 polymorphism in 5’ near gene with the risk of SLE among patients in south of Iran.
Materials and Methods: This study was performed on 102 patients with SLE in comparison with 118 healthy controls. Genotyping of the GADD45A rs581000 polymorphism was performed using T-ARMS PCR.
Results: The T allele was significantly more frequent in the controls (0.13) than in the patients (0.01) with SLE (p<0.001). The frequency of genotypes carrying at least one C allele (CC+CG) was higher in control group (14.4%) compared to patient group (1%), and this allele showed protective effect against the risk of SLE (p<0.001, CI: 0.009-0.5, OR=0.06)
Conclusion: It seems that GADD45A rs581000 polymorphism involved in the SLE pathogenesis.
Nazli Khajehnasiri, Homayoun Khazali, Farzam Farzam Sheikhzadeh Hesari,
Volume 20, Issue 5 (8-2017)
Abstract
Abstract
Background: The advantageous effects of the regular moderate physical activity (Exercise) on reproduction is widely accepted, but until now, the alterations of the expression of hypothalamic arcuate nuclei gene affecting on reproduction axis in response to this type of physical activity are not clear. Therefore, the goal of the present investigation was to study the effect of one –month regular moderate physical activity on neurokinin B gene expression and reproductive axis hormonal changes.
Materials and Methods: In the experimental study, fourteen adult male Wistar rats were randomly divided into control and one- month regular moderate exercise groups. After one - month physical activity (20m/min), the arcuate nucleus was isolated from brain and stored in -80 refrigerators for neurokinin B gene expression assay by Real-time PCR method. In addition, serum samples were taken to assess the corticosterone, luteinizing hormone and testosterone levels by ELISA method. Data were analyzed by Independent t-test in SPSS.
Results: Neurokinin-B gene expression level was lower in the group which received physical activity than the control group(p<0.05). Also, corticosterone serum concentration was decreased in the physical activity group(p<0.05). By contrast, the physical activity induced luteinizing hormone and Testosterone serum levels evaluation in exersice group compared with control group (p<0.05).
Conclusion: Regular moderate physical activity may improve male reproductive performance by reducing the corticosterone hormone level and decreasing neurokinin B expression.
Elahe Fini, Neda Nasirian, Bahram Hosein Beigy,
Volume 24, Issue 2 (June & July 2021)
Abstract
Background and Aim: Ovarian cancer is among the most common cancers in women worldwide. CA125 is the most frequent biomarker used in the screening for ovarian cancer. CA125 has no high sensitivity and specificity as a screening test in the medical community; however, because of being simple and noninvasive, it is almost always requested for evaluation and ruling out cancer. It plays an important role in the treatment and post-treatment process, the prediction of prognosis, and the relapse of the disease. The present study aimed to determine the relationship between a high level of CA125 tumor marker and ovarian cancer by detecting spesivity, sensivity, positive and negative predictive values.
Methods & Materials: In this cross-sectional study, all cases undergoing CA125 test in Velayat Hospital in
2017-1028 were evaluated for having ovarian cancer. In addition, the CA125 level was compared between healthy individuals and patients with ovarian cancer. Finally, the obtained data were analyzed using SPSS.
Ethical Considerations: The present study was approved by the Qazvin University of Medical Sciences (Ethics Code: IR.QUMS.REC.1396.316).
Results: In this study, 35.3% of the study participants received a definite diagnosis of ovarian cancer. Generally, CA125 values were negative in 41.8% and positive in.58.2% of the study subjects. The sensitivity of the test was measured as 80.1%, the specivity as 53.6%, the positive predictive value equaled 48.4%, and the negative predictive value was measured as 83%. There was a significant relationship between age and the presence of ovarian cancer, and serum CA125 levels.
Conclusion: The present study suggested that age and the serum level of CA125 were statistically significant. Finally, CA125 levels were significantly related to ovarian cancer. It provided moderate specivity and specivity as well as low positive predictive value and high negative predictive value as a tumor marker; it is valuable for ruling out of tumor but not appropriate as a screening test.
Saeed Nasiri, Mohammad Noori, Maryam Aslezaker,
Volume 24, Issue 5 (December & January 2021)
Abstract
Background and Aim: Attention Control Training is a new cognitive intervention that improves emotion regulation by reducing attentional bias towards negative information. Given the significant association between death anxiety and emotion dysregulation and death-related attentional bias, this study aimed to assess attention control training as an intervention for reducing death anxiety.
Methods & Materials: In this clinical trial, the Convenience Sampling Method sampled 50 university students in Tehran and was randomly assigned to 2 experimental and 1 control groups. Attention control training was delivered using death-related stimuli for the 1st experimental group and negative stimuli unrelated to death for the 2nd experimental group. The control group didn’t receive any interventions. In 3 measurements of pretest, posttest, and 3 months follow-up, death-related attentional bias, death anxiety, and sensitivity to mortality salience were assessed, respectively, using the Modified Stroop Test, Multidimensional Fear of Death Scale (MFODS), and Propensity to Moral Disengagement Scale (PMDS) after inducing Mortality Salience condition.
Ethical Considerations: This study was registered at the Iranian Registry of Clinical Trials (Code: IRCT20190406043181N1) and was approved by the research ethics committee of Shahid Beheshti University of Medical Sciences (Code: IR.SBMU.MSP.REC.1398.539).
Results: The study showed that after completing attention control training, the 1st experimental group’s death-related attentional bias, death anxiety, and sensitivity to mortality salience were significantly reduced (P<0.05), and this reduction was maintained at 3 months of follow-up. No significant changes were observed in the other two groups (P>0.05).
Conclusion: Based on the results of this study, it can be concluded that attention control training is capable of significantly reducing death-related attentional bias, and this reduction in attentional bias leads to decreased death anxiety and sensitivity to mortality salience
Ms Nafise Mohamadi Farsani, Doctor Ebrahim Nasiri Formi, Ms Zohre Khodadadi Jahromi,
Volume 25, Issue 4 (October & November 2022)
Abstract
Introduction: The period of the epidemic of covid-19 is a critical situation where the operating room personnel are in the front line and are in more contact with the sick patient and his respiratory tract. The purpose of this study is to determine the preventive behaviors of operating room personnel of Isfahan teaching hospitals during the epidemic of Covid-19.
Methods: In this cross-sectional descriptive study, 100 operating room personnel of Isfahan teaching hospitals were investigated in 2019-1400. The required information was collected with the help of demographic information questionnaires and a standard questionnaire of specific questions related to preventive behaviors. Data collection was done from March 1999 to June 1400, then it was analyzed by SPSS statistical software. The Research Ethics Committee of Sari University of Medical Sciences has registered this study with the code IR.MAZUMS.REC.1400.115.
Results: The average rate of compliance with preventive behaviors among operating room personnel was 64.53%, which was above the average level. The highest compliance rate was preventive behaviors after the patient with corona virus left the operating room (84.50%). In this research, 100 health care personnel of operating rooms participated in the study. The gender of the majority of them (74%) was female and 63% of them were under 30 years of age. The participants stated that after the patient with corona virus leaves the operating room, they often or always dispose of the patient's consumables correctly (85%), complete disinfection. It was done with detergents (87%), using UV rays (86%), storing and transporting samples in special double-layered containers and fully complying with hygiene principles (83%).
Conclusions: The results showed that at the time of admission of the patient without Covid 19, contraceptive protocols were observed to a lesser extent than when the patient with Covid was admitted. Preventive behaviors and staff knowledge and awareness about the proper use of personal protective equipment can play an effective role in reducing their incidence.
Amir Hossein Zahirnia, Amir Lorzadeh, Hassan Nasirian, Behroz Davari,
Volume 26, Issue 6 (February & March 2024)
Abstract
Introduction: Head lice (Pediculus capitis) infestation is considered an important hygienic problem in developing countries. The aim of study was to compare 1% permethrin shampoo and 4% dimethicone lotion effects for treatment of infected head lice students in primary girl schools in Gotvand County, Khuzestan province.
Methods: The studied population was first- to sixth-grade students in elementary schools. Positive cases with head lice after identification (304 persons) were randomly divided into two treatment groups. Permethrin shampoo and dimethicone lotion were allocated for the first and the second groups, respectively. The drug therapeutic effects were studied after 7, 14 and 21 days after treatment. Data were analyzed by Chi-square test using SPSS software.
Ethical Considerations: This study was approved by the Ethics Committee of Hamadan University of Medical Sciences (Code: IR.UMSHA.REC.1399.778).
Results: In total, 304 students participated in the study. The age of students ranged between 7 and 12 years which 47.7% of them were between 7 and 8 years. Also 60.9 and 39.1% of them were in urban and rural schools, respectively. The drug effectiveness were 46.1, 69.5 and 100, and 77.6, 85.3 and 100% for permethrin and dimethicone in the first, second and third intervals after treatment, respectively. There was a significant difference between the effect of drugs in the first interval (P = 0.00) after treatment but there was not a significant difference between the second (P = 0.084) and the third (P = 0.43) intervals after treatment.
Conclusions: It is recommended the use of dimethicone lotion and permethrin shampoo as the first and second option, respectively in eliminating the head lice infestation in primary girl schools.
