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Showing 5 results for Mokhtari

Hadi Hasankhani , Eisa Mohammadi, Farhad Moazami , Manijheh Mokhtari, Mohammad Mahdi Naghizadeh,
Volume 6, Issue 4 (Winter 2003)
Abstract

Introduction: Postoperative hypothermia is physiologically stressful by elevating blood pressure, heart rate and plasma catecholamine concentration. This study conducted to evaluate the effects of intravenous fluids temperature on perioperative hemodynamic situation.
Materials and Methods: This was a randomized clinical trial study Perioperative pulse rate, blood pressure, intraoperative esophageal and skin temperature were measured in 60 volunteer patients undergoing orthopedic surgeries subjects randomly divided into two groups according to intraoperative IV fluids management. In 30 patients (hypothermia group) all IV fluids infused were at room temperature. In the other 30 patients (normothermia group) all IV fluids were warmed using and dry IV fluid warmer.
Results: The core and skin temperature of hypothermia and normothermia group decreased significantly from induction of anesthesia toward end of surgery but its reduction was more in hypothermia group (P<0.005). Postoperative mean arterial blood pressure increased significantly more in hypothermia group versus normothermia group (P<0.005). Shivering was observed in 21 of 30 hypothermia and 11 of 30 normothermia group (p<0.005) and recovery time was significantly lower in normothermia group (36±5 vs. 26±3 min, P<0.005).
Conclusion: Infusion of warm fluids helps to reduce the variation of postoperative mean arterial blood pressure, core and skin temperature, occurrence of shivering and recovery time.

Ahmad Ameri, Jamshid Ansari, Majid Mokhtari, Ali Chehrei,
Volume 9, Issue 4 (12-2006)
Abstract

Introduction: Radiotherapy after breast cancer surgery will increase local control of the disease and also increase overall survival. Radiation have some side effects on lung function. In different radiotherapy techniques, these side effects are different. Pulmonary function tests and oxygen saturation are methods for evaluation of these complications. In this study we decide to campare pulmonary complications in two radiotherapy methods. Materials and Methods: In this clinical trial study fifty one patients with breast cancer in stage II and III according to TNM staging system, which were under modified radical mastectomy in Imam Hosein hospital and refered for adjuvant radiotherapy, randomly divided in two groups. In one group patients were treated with three field technique and in others with four field technique. All patients received total dose of 48-50 Gy. For patients, pulmonary function test and pulse oxymetery were done once before initiation of radiotherapy and then one and three months after radiotherapy. Results: Measurement of FEV1 , FVC and show that no significant statistical difference was present between the two groups one month and three months after radiotherapy, also in each of the two groups the amount of FEV1 , FVC and one month after radiotherapy had no significant statistical difference in comparison to baseline tests but FEV1 and FVC after three months was decreased and had significant statistical difference respectively (p<0.001, p<0.006). SO2 had no significant defference between the two groups and also in each group after one and three month of radiotherapy. Conclusion: Locoregional radiotherapy of breast and lymph nodes areas causes a decrease in some parameter of pulmonary function tests but no difference was present between three field and four field techniques.
Simin Namvar Aghdash, Mansoure Mokhtari,
Volume 18, Issue 12 (3-2016)
Abstract

Background: Traditional medicinal herbs have remained as a component of disease treatment system of many societies in the world. Today, many scientists have paid attention to the use of medicinal herbs in the treatment of epileptic seizures, because epilepsy is one of the most common neuropsychological disorders in the world that have many serious physical, psychological, social, and economic consequences. The aim of this study was to investigate the effect of Chelidonium Majus extract in the treatment of seizure.

Materials and Methods: In this study 40 mice have been randomly chosen and divided into 5 groups including a control group that received only pentylenetetrazol, sham group that received distilled water and 3 experimental groups received aqueous extract of Chelidonium Majus in doses of 50,100 and 150 mg/kg for 4 weeks. 30 minutes after gavage with different doses of the extract or distilled water, pentylenetetrazol was injected to experimental and sham groups. Animals immediately were transferred to a special cage and the seizure behaviors and parameters were recorded by a camera. Then, the different phases of seizure, latency time for onset of seizure and seizure duration were evaluated.

Results: Data analysis indicated that the aqueous extract of Chelidonium Majus had a significant effect on PTZ-induced seizure.  Therapy by this extract increases latency time for onset of seizure and prevents progress of seizure phases.

Conclusion: The attained results showed that Chelidonium Majus extract has anticonvulsant effect on PTZ-induced seizure. Thus, it may be used in seizure treatment.


Leila Hamidi, Saeed Khatamsaz, Mohammad Javad Mokhtari, Mohammad Ali Babaei Beigi,
Volume 20, Issue 8 (11-2017)
Abstract

Abstract
Background: Coronary artery disease (CAD) is a multifactorial disorder, which remains asymptomatic for many years. Genetic and environmental factors are involved to this disease. In the past years , the role of apolipoproteins and their polymorphisms has been identified in the diseases.The aim of this study was to evaluate the correlation between gene polymorphisms of apolipoprotein A1 with diabetes, hypertension and cigarette smoking in CAD sufferers in Fars province.
Materials and Methods: This study evaluates the promoterregion polymorphisms up to intron 2 of APOA1 genes in 75 CAD cases and 75 controls. The method used to determine these polymorphisms was PCR sequencing. This case-control study was performed by odds ratio (OR, with a confidence interval of 0.95) to reveal the association of these polymorphisms with hypertension, diabetes and smoking in CAD patients.
Results: Four polymorphisms were identified in this area. The genotypes of AA in 12718466, GA in rs 670, TC in rs5070 and CC in rs 5069 had the highest frequency in all patient groups and controls. There was a significant association in Rs12718466 between control group with diabetic group (p=0.033).
Conclusion: The results of this study indicated that diabetes, hypertension and cigarette smoking had no effects in initiation and aggravation of CAD.

 

Tayebeh Mokhtari Sorkhani, Katayoun Alidousti, Atefeh Ahmadi, Moghaddameh Mirzaee, Victoria Habibzadeh,
Volume 24, Issue 6 (February & March 2022)
Abstract

Background & Aim: Infertility is defined as inability to become pregnant with regular sexual intercourse for more than one year without using preventive methods. Infertility has negative effects on the quality of life of infertile couples. this thesis was done with the purpose of investigating the effecte of infertility counseling to improve the quality of life among infertile couples
Materials and Methods: This randomized clinical trial was carried out on sixty infertile couples with primary infertility in2017. Samples were allocated to an intervention (30 couples) and a control group (30 couples) by simple randomization. Even days of the first week, the intervention group and in the odd days, control group samples were selected, and the opposite was done in the following week. The intervention group received infertility counseling for six forty-five-minute sessions twice a week. However, control group received routine care. FertiQoL questionnaire was completed before and after intervention. For data analysis SPSS 19 software and Paired T-Test statistical tests , Mann-Whitney and Chi-Square Test, were used.
Ethical Considerations: Ethical code is IR.KMU.REC.1395.678  in Kerman University of Medical Sciences
Findings: Comparison of the differences between the mean of quality of life in the intervention and control groups before counseling and after counseling indicated  that infertility counseling increased Meaningful quality of life in the intervention group (p <0.0001) 
Conclusion: The results indicated infertility counseling can improve the quality of life among infertile couples. Therefore, it can lead to more satisfaction and cooperation in infertility treatment.

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