Ali Hekmatnia, Iman Fani, Ali Fani, Masoud Fazeli, Javad Marashi,
Volume 12, Issue 4 (2-2010)
Abstract
Background: The use of proper contrast agents is very effective in improving the quality of medical imaging. In this study, we dealt with the effect of high PH blackberry juice accompanied with omeprozole in reducing the upper fluid artifact in MRCP images. Methods: This single blinded before-after clinical trial was done with the enrollment of 34 patients. After receiving official agreement from the patients and applying the enrollment criteria, they were ordered to take two 20mg omeprozole capsules the night before the exam. The next day, while they had been held NPO, they were exposed to the first MRCP. After this, they drank 300cc blackberry juice and were re-examined after 15 minutes. The related checklists were printed and three radiologists independently inspected the reduction of artifact checklists and the resolution of images. Eventually, the quality of images and the mean of artifact reductions in the images before and after black berry Juice consumption were compared. Results: Reduction of artifact scores due to gastrological secretions did not show any significant differences before and after black berry juice consumption (2.97±0.37 and 2.89±0/87, respectively). Additionally, no significant changes were observed in the visibility of gall bladder, water ampoula, common hepatic duct, intrahepatic ducts and head of pancreatic duct images. There was a decrease in the common bile duct visibility (p=0.01). In the case of pancreatic duct tail and body visibility, images showed improvements (p=0.04 and 0.03, respectively). Conclusion: Blackberry juice, as a contrast agent, does not seem to have enough paramagnetic metals and does not improve the quality of MRCP.
Alireza Khodavandi, Fahimeh Alizadeh, Nedasadat Marashi,
Volume 20, Issue 11 (2-2018)
Abstract
Abstract
Background: Biofilm formation represents one of the major virulence factors of Candida albican. However, the number of antifungal drugs is limited for the treatment of candidiasis. Combination therapy is one of the most frequently used techniques to alleviate this problem. In this study, we aimed to evaluate the antifungal activity of fluconazole and terbinafine alone and in combination on C. albicans biofilm inhibition.
Materials and Methods: In this cross- sectional study, 10 clinical isolates of C. albicans were identified from the immunocompromised patients. Antifungal susceptibilities were performed using the CLSI standard reference method. The crystal violet colorimetric method, direct microscopic observation and expression of HWP1 gene at different concentrations based on MICs were carried out to investigate inhibition of biofilm formation in C. albicans treated alone and in combination with fluconazole and terbinafine.
Results: The data indicated that combination of fluconazole with terbinafine exerted synergistic effects with fractional inhibitory concentration index ranged from 0.375 to 1.5. The combination of fluconazole with terbinafine reduced the number of yeast form and inhibited the biofilm formation. Finally, the expression level of HWP1 was down regulated (p< 0.05).
Conclusion: These results suggest the possibility of fluconazole/ terbinafine to treat candidiasis with a higher efficiency. In addition, HWP1 gene could be probable target in synergistic interaction of fluconazole/ terbinafine against C. albicans biofilm.
Farideh Barghi, Sahar Safarzadeh, Faremah Sadat Marashian, Saeed Bakhtiarpour,
Volume 25, Issue 6 (February & March 2023)
Abstract
Introduction: Since a more appropriate psychological treatment has not yet been found in the treatment of autism to be a definite solution in autism, in this research, two more common psychological methods have been compared. Objectives The aims of this study were to compare the effectiveness of ABA and Fluortime play therapy on sensory processing in children with autism spectrum disorder in Qom in 1401.
Methods: The method of this quasi-experimental study was pre-test-post-test and follow-up with a control group. The statistical population of the research included all the children with autism in land Qom at Golhay Behesht Autism Center. The statistical sample of this research was 45 people who were selected by available sampling, and randomly divided into three experimental groups using the ABA method (15 people Fluortime method (15 people) and the control group (15 people) were placed. The first experimental group was treated with the method of ABA in the designated sessions. 23 20-minute sessions were presented to the subject group. During experimental group Fluortime was treated with the method of 23 sessions of 20 minutes, it was presented to the subject group, then it was analyzed using analysis of variance with repeated measurements. Ethical Considerations: This article is approved by the ethics committee of Islamic Azad University Ahvaz branch IR.IAU.AHVAZ.REC.1401.032.
Results: The results of the analysis showed that the Flortime play therapy training in sensory processing was significantly at the level of the effect of the implementation of independent variables on the registration components down (P = 0.02) Sensory seeking (P = 0.001) Sensory sensitivity (P = 0.019) Sensory avoidance (P = 0.004) is significant. On the other hand, the average difference of sensory processing components in the applied behavior analysis and game group is significant. Fluortime treatment is significant with the control group. So that the mean of the components of sensory processing in both experimental groups has a significant0.05 ≥ P decrease compared to the control group.
Conclusions: This finding, in line with the change trend of the mean of the components of sensory processing, shows that functional ABA and Fluortime play therapy during the implementation period. And three months after the completion of the implementation period, it has led to a significant decrease in the average scores of sensory processing components. Sensory processing in children with autism spectrum disorder. It should be mentioned that in comparison, the scores of sensory seeking, sensory sensitivity and sensory avoidance in the Fluortime were higher than in the ABA method, and low registration was higher in the ABA method, but the results of the Ben Feroni test show that although each method was significant separately in sensory processing, the difference in effect Functional behavior analysis and Fluortime play therapy on sensory processing components of p>0/05 is not significant.
