Mahmood Reza Nakhai, Vali Razavieh , Reza Mahdavi, Mohammad Reza Palizvan, Siros Madadi Noie,
Volume 7, Issue 3 (Autumn 2004)
Abstract
Introduction: Impressive research demonstrates the importance of essential fatty acids for many physiological and bahavioral mechanisms in both human and animals. Essential fatty acids must be supplied via the diet. In this study we assessed the dietary effects of cis and trans fatty acids on seizures induced by pentylenetetrazol in rats.
Materials and Methods: In this study animals were divided into four groups. In the test groups cis, trans or cis and trans fatty acids were add to the standard foods of rats and in control group only standard food was dietary administrated. After one month kindling was established in rats with PTZ in subconvulsive dose (45 mg/kg). convulsing activities were monitored for 20 min.
Results: Results showed that there was no meaningful difference between rat groups receiving cis, trantary administration of cis and trans fatty acids had no effect on penylenetetrazol kindling in rats.s or cis and trans fatty acids in their standard food.
Conclusion: It was concluded that dietary administration of cis and trans fatty acids had no effect on pentylenetetrazol kindling in rats.
