Abstract
Background: The aim of this study was to investigate the effect of four weeks exercise prior preparation before Alzheimer's induction on the levels of nerve growth factor and beta amyloid in the hippocampus of Wistar male rats
Materials and Methods: 84 male Wistar rats (8 weeks old) with a weighing average of 20 ± 195 grams from Pasteur Institute of Iran were prepared, and rats were randomly divided to two exercise (4 weeks aerobic training on a treadmill with a gradient of 0 degrees, 5 days a week for 4 weeks) and rest groups. Then, the rats of each group were randomly assigned to 3 sub groups of 14 numbers, injection Aβ1-42, control, and non-injected. 48 hours after the last exercise session, injections into the hippocampus amyloid beta or Dimethyl sulfoxide were performed. Seven days after surgery, the rats of each group were randomly sacrificed or subjected to behavioral testing. To determine the levels of of nerve growth factor and beta amyloid Sampling was performed from the hippocampus and plasma of animals, a Morris water maze test was used for spatial memory test. Kolmogorov-Smirnov test (KS) and analysis of variance were used to analyze the data.
Results: The results of one-way analysis of variance showed that there was a significant difference between the levels of amylohyd of hippocampus and NGF in different groups. Also, the results of the probe test for spatial memory showed that the time spent on the target circle in the Aβ1-42 injection group was significantly lower than the other groups (p≤ 0.01). Also, the exercise and exercise + sham groups had a significantly better performance than control group.
Conclusion: It seems that performing physical activity before induction of Alzheimer's in rats is a kind of countermeasures and preeclampsia with physiological disorders and progression of the disease.
 

Introduction: The period of the epidemic of covid-19 is a critical situation where the operating room personnel are in the front line and are in more contact with the sick patient and his respiratory tract. The purpose of this study is to determine the preventive behaviors of operating room personnel of Isfahan teaching hospitals during the epidemic of Covid-19.
Methods: In this cross-sectional descriptive study, 100 operating room personnel of Isfahan teaching hospitals were investigated in 2019-1400. The required information was collected with the help of demographic information questionnaires and a standard questionnaire of specific questions related to preventive behaviors. Data collection was done from March 1999 to June 1400, then it was analyzed by SPSS statistical software. The Research Ethics Committee of Sari University of Medical Sciences has registered this study with the code IR.MAZUMS.REC.1400.115.
Results: The average rate of compliance with preventive behaviors among operating room personnel was 64.53%, which was above the average level. The highest compliance rate was preventive behaviors after the patient with corona virus left the operating room (84.50%). In this research, 100 health care personnel of operating rooms participated in the study. The gender of the majority of them (74%) was female and 63% of them were under 30 years of age. The participants stated that after the patient with corona virus leaves the operating room, they often or always dispose of the patient's consumables correctly (85%), complete disinfection. It was done with detergents (87%), using UV rays (86%), storing and transporting samples in special double-layered containers and fully complying with hygiene principles (83%).
Conclusions: The results showed that at the time of admission of the patient without Covid 19, contraceptive protocols were observed to a lesser extent than when the patient with Covid was admitted. Preventive behaviors and staff knowledge and awareness about the proper use of personal protective equipment can play an effective role in reducing their incidence.