Showing 21 results for Kamran
Kamran Moshfegi,
Volume 1, Issue 1 (Winter 1996)
Abstract
This article has no abstract.
Kamran Moshfegh,
Volume 1, Issue 3 (Summer 1997)
Abstract
Turner syndrome caused by complete or relative deletion of short arm of x chromosome. Short stature, primary Amenorrhoea and gonadal disgenesis are the main signs of the syndrome, but mental retardation is not the main sign of the syndrome. There are cardiovoiscular, renal, urinary and endocrine complication in syndrome.Caryotyping should be performed to diagnose suspicious patients strogentherapy used for these patients from about 15 years old.
Ghasem Mosayebi , Khaki Mohsen, Kamran Moshfeghi ,
Volume 1, Issue 4 (Autumn 1997)
Abstract
Seral of 121 vasectomized and 45 samples of normal individuals examined by tray agglutination test for Anti-Spem Antibodies(ASA). ASA were found in more than 83% of vasectomized and 6.5% of control subjects. The Presence of ASA in two groups has been significantly different. (P<0.0001). Enhancement of ASA titer showed a positive correlation with the post time after vasectomy.
Kamran Moshfeghi, Mohammad Rafii,
Volume 4, Issue 4 (Winter 2001)
Abstract
Introduction: Iron deficiency anemia is the most common type of anemia in the world and the most important disease which has overlapping diagnosis with it is & thalassemia minor. For diagnosis of theses two diseases, serum ferritin measurement and hemoglobin laboratories throughout the country now, finding some tests which are easier. More available and cheaper for different of these two mentioned diseases, are useful. Therefore in this article, reticulocyte counting test, after a short period of iron consumption, was evaluated.
Material and Method: This study is descriptive and cross-sectional. The sample population consists of 69 patient with hypochromic microcytic anemia which serum ferritin measurement, reticulocyte counting and hemoglobin electrophoresis for each of there were done. After 7 days treatment with oral iron tablet, reticulocyte counting test for each of them was done. If reticulocyte counting test had increased, the patient was considered as iron deficiency anemia, on the other hand, the results of reticulocyte count test was compared with serum ferritin test and hemoglobin electrophoresis results and then, sensitivity as well as specificity of mentioned test, were analysised.
Results: Sensitivity and specificity of mentioned test for iron deficiency anemia were 82 and 67 percent and in B thalassemia minor were 64 and 78 percent, respectively. These results show high sensitivity of this test for iron deficiency anemia and high specificity for B thalassemia minor.
Conclusion: It seems that, in circumstance which serum ferritin measurement and hemoglobin electrophoresis aren’t available, applying reticulocyte count test for deferenciation of these two diseases, is helpful.
Kamran Moshfeghi, Mohammad Rafiee,
Volume 5, Issue 3 (Autumn 2002)
Abstract
Introduction: The relation between Helicobacter pylori with iron deficiency is being studied in recent years. The aim of this study is finding the relation between Helicobacter pylori with the rate of hemoglobin and serum ferritin.
Material and Methods: This study is an observational study and a cross-sectional type which is done analytical-descriptive against 262 patients suffering from anemia and for each patient the amounts of Hemoglobin, MCV, serum ferritine and Helicobacter IgG titre is calculated and then the relation between these amounts and Helicobacter is evaluated.
Results: In 147 patients (56%), Helicobacter IgG antibody was negative. In 78 cases (29.8%) the serum ferritin was less than 120 µgr/dlit. Using statistical analysis (Logistic regression) revealed that there was a statistical relation between the amount of ferrittin and the chance of strickened with Helicobacter in individuals whom their ferrittin rate was less than 12, 1.93% of patients whom their ferrittin is more than 12 and the enhance is significant. By the way it was cleared that there is not any significant statistical relation between MCV reduction and the chance of being strickened with Helicobacter.
Conclusion: Serum ferrittine rate in patients with Helicobacter pilory infection reduced and this reduce was significance. Previous studies in other countries indicated to this issue.
Kamran Moshfeghi, Nader Dadgar, Mohammad Rafiee,
Volume 6, Issue 4 (Winter 2003)
Abstract
Introduction: Nearly, 6% of recently diagnosed cancer in the United States was upon to lymphoproliferate and leukemia and 9% of fatality in cancerous people was upon to these two illnesses. Using some simple, cheap and in-hand tests and special consideration to clinical inspections in suspected subjects provide a faster diagnostic and suitable treatment. It may ultimately promote the quality of life and decline the fatality among patients.
Materials and methods: This was a cross-sectional investigation which carried out during a 1.5 years in the form of forward direction. Forty-two lymphoproliferate (28 lymphoblast and 14 Hotchkin) and 21 acute lymphoblastic leukemia (10 acute lymphoblast leukemia and 11 miloid acute leukemia) subjects were evaluated. ESR, LDH and ALP levels were measured in all patients. In clinical examinations, oversizing of lymph nodes, spleen and liver were exactly considered.
Results: According to our results the best tests to rule in and rule out acute leukemia from lymphoprolifeatives were ESR and LDH, respectively. Additionally, The most sensitive and specific evaluations to rule out these two diseases were LDH and oversizing of liver inspection. It was also determined that LDH is the best screening test to rule out leukemia from lymphoproliferate.
Conclusion: Using of simple examinations such as ALP, LDH, ESR and more consideration to oversized spleen, liver and lymph nodes in each suspected patients, we could easily differentiate lymphoproliferate and acute leukemia from each other.
Ghasem Mosayebi , Kamran Moshfeghi, Mohammad Moazzeni, Fazel Shokri ,
Volume 7, Issue 4 (Winter 2004)
Abstract
Introduction: different isotypes of antibody can be produced by immune system after antigen contact. Detection and measurement of different classes of antibody against the antigen is very important in some cases. The aim of this study is designing of an ELISA method on the basis of inhibition of enzyme activity by using a non-competitive inhibitor. Therefore in this study rheumatoid factor is used as a model for the detection of different other classes of antibodies against the antigen.
Materials and Methods: In this cross sectional analytical study, we measured IgM and IgA rheumatoid factors in sera of 10 patients with rheumatoid arthritis and positive latex test , by mixed and routine ELISA. In mixed ELISA the activity of the first conjugated enzyme was blocked by a non-competitive inhibitor after adding the substrate. Then the next conjugated antibody, which was specific for another isotype, was added. By optical density, results was comparisoned with routine ELISA.
Results: The obtained results showed that the average optical density is lower when compared with routine ELISA , but the difference is not statistically significant. however these two methods did not show any significant difference in quantifying antibody isotypes. Also there is a positive association between mixed and routine ELISA (r=0.9, p=0.001).
Discussion: Lower optical density in mixed ELISA is probably because of stick hindrance by the first conjugate. So, because there is no significant difference between the results of these two types of ELISA, and also no need to repeat the test for each isotype in this method, it is recommended to use the new method instead of the routine one to save time and reagents.
Mahbobeh Sajadi Hezaveh, Bahman Salehi, Kamran Moshfeghi,
Volume 11, Issue 3 (9-2008)
Abstract
Background: Breast cancer is the most prevalent type of all cancer in women. In this study form various methods for treatment of depression due cancer. This study conducted for comparison drug therapy and drug-cognitive therapy on decreasing depression, effect of drug and cognitive theray on decreasing depression. Methods and Materials: This is a clinical trial study. Form patient refered to oncology clinic and ward of vali-e-Asr hospital 78 women were selected by simple sampling. Based on Beck depression test, 42 of them had depression. They randomly divided to case and control groups. Both groups received antideresant drug as usual. But case group had also cognitive- drug therapy. Afrer 6 Month treatment both group were tested again for depression. Data was analyzed by spss using independent and paired t tests. Results: The mean depression score hadnot signigiant difference between case and control grops beor and after treatment. The mean depression score in control group had no significant deference before and after treatment the mean depression score in the case group was significantly different after treatment (p<0.05). The mean score of depression in control group was more than case group after treatment. Conclusion: In the present study cognitive therapy cause a significant decrease in depression score of case group.
Keyvan Ghasami, Akram Asghari, Fereshteh Naranji, Kamran Moshfeghi, Babak Eshrati,
Volume 12, Issue 4 (2-2010)
Abstract
Background: Tension headaches are the most basic reasons for referring to physicians throughout the world. Iron anemia, on the other hand, is the most common type of anemia among women who are in productive age in the world. This study was done to investigate the relationship between vascular headaches and iron anemia and to see the effect of iron tablets administration on the treatment of these headaches in women who are in productive age. Materials and Methods: In this quasi-control study, 50 women in reproductive age who had iron anemia and vascular headaches, referring to the neurologic clinic of Vali-asr Hospital in Arak, were selected and treated with ferrous sulfate tablets for three months. For verifying the treatment, patients' hemoglobin was monitored after one month, and in case of any significant increases in this value, the patients discontinued participating in the study. The number of headache attacks and the number of analgesics used before, through and three months after beginning the administration of ferrous sulfate were noted for all of the patients. Results: The mean number of the headache attacks one month before treatment, during the treatment and three month after the treatment were 19.6±28 , 14.2±11.2 , 13.3±11.8, respectively (p=0.0001) . In addition, the mean number of used analgesics before the treatment, through the treatment and three month after the treatment were 30.1±14.1, 14.3±11.2, 13.1±16.1, respectively (p=0.0001). Conclusion: It seems that using iron tablets can be useful in treatment of vascular headaches.
Shabanali Alizadeh, Kamran Moshfeghi, Mssoumeh Kalantari, Khadijeh Ebrahimi,
Volume 12, Issue 4 (2-2010)
Abstract
Background: The existence of estrogen and progesterone receptors, p53, human epidermal receptor-2(HER-2) and cathepsin-D are among the prognostic markers for breast cancer. In this study, we investigated the relationship between these factors and lymph-node involvement. Materials and Methods: In this case-control analytic study, 105 patients with breast cancer were investigated. After detecting breast mass, surgical biopsy was done and the status of the estrogen and progesterone receptors, p53, HER-2, and cathepsin-D were studied. Collected data were registered in a checklist and were subjected to analysis. Results: There was no relationship between lymph-node involvement and estrogen and progesterone receptors, p53, cathepsin-D and HER-2. Conclusion: In order to get more precise results about hormonal receptors, p53, HER-2 and cathespin-D, a similar research with a larger sample size over a longer period of time is needed.
Hamid Reza Jamilian, Kamran Bagherzadeh, Zeinab Nazeri,
Volume 14, Issue 6 (February-March 2012)
Abstract
Background: Major depression is one of the most prevalent psychiatric diseases, whereas schizophrenia is one of the worst human diseases. Therefore, finding low-cost treatment methods with few side effects can be of great help to patients. The present study was done to compare the serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous in individuals with major depression and schizophrenics with healthy subjects.
Materials and Methods: In this cross-sectional study, serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous were assessed in 100 major depressive, 100 schizophrenic, and 100 healthy subjects. Subjects with a history of renal failure, hepatic failure, parathyroid disease, and consumption of vitamin D, parathyroid hormone, calcium, and phosphorous supplements were excluded from the study. SPSS software version 15 was used for data analysis.
Results: Depression was accompanied with decreased serum levels of vitamin D and increased serum levels of parathyroid hormone (p>0.001, p=0.01), but there was not a significant difference between depression and healthy subjects in calcium and phosphorous serum levels (p=0.69, p=0.15). Schizophrenia presented a significant correlation with decreased serum levels of vitamin D and phosphorous (p>0.001, p=0.01), but there was not a significant difference between schizophrenic and healthy subjects in calcium and parathyroid hormone serum levels (p=0.47, p=0.67).
Conclusion: Since depression and schizophrenia are accompanied by decreased serum level of vitamin D, consumption of supplementary vitamin D can be helpful in the treatment of these patients.
Aliarash Anoushirvani, Kamran Moshfeghi, Mohammad Rafiee, Saeedeh Bakhshi,
Volume 15, Issue 8 (January 2013)
Abstract
Background: Immune thrombocytopenic purpurais an acquired disorder. Conventional treatment of immune thrombocytopenic purpuraincludes prednisolone (1mg/kg/day). Customarily, steroidsareadministered for about 3-6 weeks however,steroids have several side effects. The aim of this study was to compare theefficacy of two and three-week prednisolone therapy in patients with immune thrombocytopenic purpura Materials and Methods: In this randomized clinical trial, 66 patients with confirmed immune thrombocytopenic purpurawho had referred to KhansariHospital, Arak, were randomly selected and administered prednisolone (1mg/kg/day) for two and three weeks alternatively. Patients’ platelet count and complications associated with the treatment (diabetes and hypertension) were compared. Results: At the end of the treatment course, there was not a significant difference in mean platelet count between the two groups (p=0.748). Side effects in two and three-week protocols were 15.2% and 18.2%, respectively however, distribution of the complications (side effect) in the two groups was equal (p=0.9). Conclusion: Considering the absence of significant differencesin mean platelet count between the two groups at the end of the two treatment protocols and the higherpercentageof side effects in the patients that had received the three-week prednisolone therapy protocol, it seems that the two-week course of immune thrombocytopenic purpuratreatment is as effective as the three-week protocol.
Davood Bashash, Seyed H. Ghaffari, Maryam Kazerani, Kebria Hezaveh, Kamran Alimoghaddam, Ardeshir Ghavamzadeh,
Volume 15, Issue 9 (February 2013)
Abstract
Background: Since nearly 90% of patients with acute promyelocytic leukemia (APL) have high telomerase activity and significant shortened telomere length, these patients have, therefore, been suggested to be good candidates for the therapeutic intervention with telomerase inhibitors. This study was done to investigate the effects of BIBR1532, a non-nucleoside inhibitor of telomerase, on APL cells. Materials and Methods: In this experimental study, for investigating the effect of BIBR1532, NB4 leukemic cells were cultured in the presence of various concentrations of BIBR1532. Succeeding apoptosis assay, Caspase-3 activity assay, and quantitative real-time PCR were applied to examine the effect of this drug on apoptosis percenage, enzymatic activity of Caspase-3, and quantitative expression of genes mRNA involved in apoptosis. Results: The results showed that BIBR1532 induced apoptosis in NB4 cells in a dose-dependent maner. Moreover, real time PCR results showed that BIBR1532 led to a significant decrease in mRNA of Bcl-2 gene and signficant increases in transcription of Bax, PUMA, and Caspase-3. Conclusion: Since treatment with BIBR1532 could exert rapid apoptotic cell death in NB4 cells andactivate cellular apoptosis route, anti-telomerase-based therapy can regarded as a suitable strategy for APL treatment. Patients with progressive shortening of telomere length and high levels of telomerase activity are suitable candidates for treatment with telomerase inhibitors.
Morteza Sadeghi, Zohreh Hojati, Kamran Ghaedi,
Volume 17, Issue 8 (11-2014)
Abstract
Background: Vascular endothelial growth factor (vegf) is one of the most important regulator of angiogenesis, there are some reports about the relation of VEGF over expression and progression of tumor in several cancers. The aim of this study is assay of four VEGF isoforms expression in breast cancer tumor samples.
Materials and Methods: 25 breast cancer tumor samples and 25 health samples were used in this study, mRNA was extracted from each sample and then cDNA was made. The expression of four isoforms VEGF121, VEGF165, VEGF183 and VEGF189 was measured by real time reverse transcription PCR (RT-PCR) and gel electrophoresis.
Results: Among the four isoforms, VEGF165 and VEGF 121 had maximum and VEGF 183 and VEGF 189 had minimum expression level in all samples. The total expression level of VEGF had a significant increase in tumor samples in comparison with the control samples (4/6, p<0.01).
Conclusion: There is a significant relation between the VEGF over expression and breast cancer tumor formation, which it can be used as a prognosis marker of breast cancer in future.
Shahram Nazari, Sajjad Ashkani, Hadi Yousefzadeh, Fazel Agaei, Gharib Majidi, Aziz Kamran, Payman Azghani, Ayyob Rastegar, Zohreh Nazari, Soudabeh Alizadeh Matboo,
Volume 18, Issue 12 (3-2016)
Abstract
Background: Dendrimers are macromolecules with regular three-dimensional structure that have many branches. The aim of this study was to investigate the fficiency of Nano Polyamidoamine–G5 (NPAMAM-G5) dendrimers in removal of Escherichia coli, Klebsiella oxytoca, Pseudomonas aeruginosa, Proteus mirabilis and Staphylococcus aureus from aqueous solution.
Materials and Methods: In this experimental study, initially, dilution of 103 CFU/ml was prepared from each strain of bacteria. Then, different concentrations of dendrimers (0.025, 0.25, 2.5 and 25 µg/ml) in the ambient temperature (23-25°C) was added to water. In order to determine the efficiency of dendrimers in removal of bacteria, samples were taken at different times (0, 10, 20, 30, 50 and 60 min) and were cultured on nutrient agar medium. Samples were incubated for 24 hours at 37 ° C and then the number of colonies was counted.
Results: There is a direct relation between antibacterial properties of dendrimers in aqueous solution and increasing the dendrimer concentration and contact time. At a concentration of 25 μg/ml and 60 minutes, all kinds of bacteria except Staphylococcus aureus, and at 30 minutes, E. coli and Klebsiella bacteria, were removed by 100% The concentration of 2.5 μg/ml at 60 minutes of bacteria, Escherichia coli, Klebsiella and Proteus mirabilis, 100% Were removed. All concentrations of dendrimer at different times were reduced bacteria.
Conclusion: Results of this study indicated that NPAMAM–G5 dendrimer is able to remove Escherichia coli, Klebsiella oxytoca, Pseudomonas aeruginosa, Proteus mirabilis and Staphylococcus aureus from aqueous solution.
Mahsa Rostamian Delavar, Masoud Baghi, Elahe Yadegari, Kamran Ghaedi ,
Volume 20, Issue 8 (11-2017)
Abstract
Abstract
Background: Oxidative Stress and mitochondrial dysfunction leading to apoptotic death of neurons play key role in the pathogenesis of the Parkinson's disease. On the other hand، misregulation of microRNAs can cause several neurodegenerative diseases. Sirt1 and Bcl2 as two key genes, regulate pathogenic processes in neurodegenerative diseases such as mitochondrial dyfunction, oxidative stress and apoptosis.
Materials and Methods: To investigate the role of microRNAs in model of Parkinson's disease, miRWalk 2.0 and TargetScan (v7) databases were served to predict microRNA-target interactions.
Results: Possible targeting effects of different microRNAs on Bcl2 and Sirt1 genes in Rat organism were analyzed. Merging data from databases has shown that rno-miR-449a, rno-miR-182, rno-miR-211, rno-miR-34b, rno-miR-34c, rno-miR-448, rno-miR-466b and rno-miR-96 with strong possibility can inhibit expression of Bcl2 gene. Also, rno-miR-181, rno-miR-211, rno-miR-27a, rno-miR-449a, rno-miR-34c, rno-miR-30, rno-miR-200a and rno-miR-448can inhibit Sirt1 gene with high possibility.
Conclusion: According to the findings, it can be predicted that regarding to high interaction scores of rno-miR-211, rno-miR-34c and rno-miR-448 and 449awith Bcl2 and Sirt1 genes in above-mentioned databases, these microRNAs probably can have critical role in disease process. Thus, these microRNAs can be introduced as appropriate candidates for investigations in in vitro model of Parkinson's disease.
Mojtaba Rahimi Varposhti, Darioush Moradi Farsani, Kamran Montazeri, Fatemeh Tanha,
Volume 20, Issue 8 (11-2017)
Abstract
Background:
This study aimed to compare the effect of cold eye irrigation solution (BSS) and viscoelastic gel with their combination in room temperature on the dosage of sedative drugs which we use in Phacoemulsification cataract surgery.
Material and methods:
190 patients scheduled for cataract surgery under sedation were randomly divided into two equal groups. During surgery we used cold (4c) and warm (room temperature) BSS and viscoelastic gel in the first and second group respectively. For all patients we started sedation with Midazolam and Fentanyl and in case we needed additional drug we used Sodium Thiopental till we reached desired sedation level. Ramsay sedation scores (before, during and after surgery) and total sedative drug consumption were evaluated and compared between two groups and at the end of the surgery we checked the satisfaction score of patients and surgeon about the quality of sedation.
Results:
The average dosage of Midazolam wasn’t significantly different between the two groups, while the average dosage of Sodium Thiopental was significantly lower in Cold group. Also the average time of which we reached desired Ramsay sedation score and the level of Ramsay score were significantly different between the two groups.
Conclusion:
Using cold BSS and viscoelastic gel in cataract surgery in comparison of their combination in room temperature will reduce the dosage of sedative drugs which we use during surgery and help us getting a more effective sedation and gaining both a satisfied patient and surgeon.
Alireza Zoalfaghari, Hadi Bahrami, Kamran Ganji,
Volume 20, Issue 12 (3-2018)
Abstract
Abstract
Background: The present study aims to provide a comparative analysis of studies on Acceptance-Commitment and Cognitive-Behavioral interferences effectiveness on generalized Anxiety disorder.
Materials and Methods: This is a quasi-experimental research. Students at the Islamic Azad University of Toyserkan, Iran, who have been in contact with the counseling office in the educational year 2016-2017, were selected as statistical population. These students, in a diagnostic interview with a psychiatrist, met the DSM5 standards for generalized anxiety disorder and were approved by a trusted psychiatrist. Then, these selected subjects gave average or more score in beck anxiety test and were randomly divided into two groups of 20. After executing interferences for each group, data were analyzed by t-test and covariance.
Results: The findings indicated that the average acceptance and commitment interference was 12.3 (t= 16.01 and p < 0.001) and the average cognitive-behavioral interference was 11.25 (t= 10.60 and p < 0.001) on generalized anxiety disorder. Also, covariance analysis showed that ACT was more effective than CBT and f (0.03) was significant. Therefore, all hypotheses turned out to be approved.
Conclusion: The research demonstrated that both interferences are effective in treating generalized anxiety disorder, although Acceptance and Commitment interference is more effective than Cognitive and Behavioral interference.
Komeil Amini, Kamran Mansouri,
Volume 21, Issue 5 (10-2018)
Abstract
Background and Aim: Human papillomavirus (HPV) infection is a prevalent, life-threatening disease and cause of cancer among women. Therefore, in recent years, developing novel anti-HPV agents is highly regarded. The study was planned to bioinformatic screening for E1 and E2 potential inhibitors of HPV serotypes including 16,18,31,33 and 45 types from medicinal plants.
Materials and Methods: This is a descriptive-analytic study. In the first step, three-dimension structure of phytochemicals were retrieved from PubChem database and then the cell cytotoxicity and mutagenesis potential of them were evaluated. In the next step, the amino acid sequences of two key proteins of mentioned types of HPV including E1 and E2 were obtained from Uniprot database. Furthermore, the conserved and variable regions of the protein sequences were predicted using multiple sequence alignment method. Finally, the three-dimension structure of mentioned proteins was determined by homology modeling method and potential interactions of the phytochemicals with the proteins were investigated using molecular docking method through Autodock 4.2.6 software.
Findings: The results demonstrated that ursolic acid has no cytotoxicity and mutagenesis potential with appropriate physicochemical properties. Results also showed that mentioned compound had strong interaction with both E1 and E2 of all studied serotypes. Furthermore, the evaluation of ursolic acid and E1 and E2 interactions showed that amino acid is involved in conserved regions of mentioned serotypes.
Conclusion: Based on the obtained results of present study ursolic acid could be good candidate for more in vitro and in vivo studies of its anti HPV activity.
Reza Hashemi, Maryam Peymani, Kamran Ghaedi, Hana Saffar,
Volume 25, Issue 1 (April & May- 2022)
Abstract
Background and Aim PBK is a mitogen-activated protein kinase (MAPKK) among MEK1/2 and MEK7 and can phosphorylate P38, JNK, and ERK in many cellular functions. The E2F transcription factor family also belongs to a class of cellular regulators acting as oncogenes and tumor suppressors. This study aims to investigate the expression of PBK and E2F7 in the early stages of colorectal cancer (CRC) compared to advanced stages based on the experimental and TCGA (The Cancer Genome Atlas) database.
Methods & Materials A total of 32 tissue samples of patients with CRC with the approval of a pathobiologist were collected according to the examination and criteria reported from different stages. After RNA extraction and cDNA synthesis, the RT-qPCR technique was used to evaluate the expression of the desired genes in the study groups. A receiver operating characteristic (ROC) curve analysis was also used to determine the ability of each of the selected genes to differentiate the two populations: stage I+II and stage III+IV.
Ethical Considerations In all stages of this research, codes of ethics of research and publication were observed.
Results In this study, it was shown that the expression of PBK and E2F7 significantly increased in stage I+II samples compared to stage III+IV. These data were confirmed by laboratory results and information extracted from the TCGA database. Also, based on the area under curve obtained from the ROC curves, these two genes are significantly distinguishable between stage I+II and III+IV populations in CRC.
Conclusion According to the results of this study, PBK and E2F7 genes are good markers in the diagnosis of CRC.
