Showing 7 results for Javaheri
Maryam Tehranipour, Jina Khayyatzade, Reyhane Javaheri Fard,
Volume 13, Issue 1 (4-2010)
Abstract
Background: Following the reduction of neurons due to peripheral nervous injuries, the number of neuroglial cells also decline because of not receiving vital factors. The aim of this study was to determine the protective effects of curcuma longa total extract on spinal cord neuroglia cell degeneration after sciatic nerve compression in rats. Materials and Methods: In this experimental clinical- trial, Wistar rats were categorized in five groups (control, compression, treatment1, treatment 2 and treatment 3), each including six rats. For inducing the injury in the compression and treatment groups, the right sciatic nerve in the upper thigh was compressed using clamp forceps. In the treatment groups, 100mg/kg doses of the extract were injected in group1(3 times a day), group 2 (6 times a day) and in group3 ( 9 times a day). After 28 days, following being anesthetized, the rats underwent perfusion and samples were taken out of the lumbar segments of their spinal cord. Then the samples, after going through tissue processes, were cut in 7 m serial sections and stained in blue toluidine. Through the stereological quantitative technique, neuroglial cells were counted. Results: A significant decrease was seen in the number of neuroglial cells in the compression group (6913±208) in comparison with the control group (10184±791). Also, through the comparison of the compression group with treatment group 1(7077±293), treatment group2 (9372±252) and treatment group 3 (8715±252) a significant difference among dnsity of neuroglial cells in groups and 3 with conppnessin group was seen. a remarkable increase in the numerical density of neuroglial cells was obtained (p<0.05). Conclusion: Due to its antioxidant effects, curcuma longa extract increased the numerical density of neuroglia cells following the compression of the sciatic nerve. The antioxidant effects of this extract probably inactivate the apoptosis channels which have been activated due to peripheral nerve injuries.
Razieh Javaheri, Hamid-Taher Neshat-Doost, Hossein Molavi, Mohammad Zare,
Volume 13, Issue 2 (6-2010)
Abstract
Background: Psychological interventions may improve the quality of life in females with temporal lobe epilepsy through affecting their bio-psycho-social dimensions. This aim of this study was to aim assess the efficacy of cognitive-behavioral stress management (CBSM) group education on improvement of quality of life in epileptic patients. Materials and Methods: This was a case-control study with pre-post-and follow-up tests. The sample population included 26 patients, already diagnosed with temporal lobe epilepsy by neurologist and through electro-encephalography, that were randomly selected and assigned to experimental and control groups. Data were collected through the Quality Of Life Questionnaire for Epileptic patients (QOLIE- 89) that was administered in the pre-test, post-test, and follow-up test. CBSM group education was given to the experimental group in ten sessions during two months. Results: The mean of QOLIE-89 score in the experimental group showed a significantly higher increase in comparison to that in the control group (p<0.05). Conclusion: The results demonstrated the effectiveness of CBSM group education on the improvement of quality of life in females with temporal lobe epilepsy.
Navi Reza Mashaykhi, Saeid Sadrneya, Ali Chehrei, Javad Javaheri, Mojtaba Ahmadlou,
Volume 16, Issue 6 (9-2013)
Abstract
Background: Traditionally levels of cholesterol and triglyceride are used to identify individuals at risk of coronary artery disease (CAD). The aim of this study is examining the association of ApoA1 and ApoB with severity of coronary artery disease and whether these parameters are better predictor of CAD.
Materials and methods: This is a cross- sectional study. All patients that referred to ARAK amirallmomenin hospital and enrolled for coronary angiography was entered to study. Before angiography and after gathering informed consent, levels of apoA1 apoB, cholesterol, TG, LDL, VLDL, HDL and FBS were measured. The results of coronary angiography were reviewed by two experienced cardiologist separately. Severity of coronary artery disease involvement was determined by Gensini score (GS), the data were analyzed with statistical methods by SPSS software.
Results: There is a statistically significant correlation Between apoB and GS (r=0.127, p=0.047). Logistic regression model showed that among predictors for CAD entered model eg gender, age, cholesterol, TG, HDL, LDL , VLDL, ApoA1, ApoB and ApoB/Apo- A1 ratio, only ApoB and gender were proper predictors of coronary artery Disease( CAD) (p=0.002, , p=0.001). In comparison with angiography for diagnosis of CAD, ROC analysis represent that using ApoB can be useful test (p=0.047).
Conclusion: According to result of this study, using ApoB in addition to conventional parameters for assessing the patient at risk to having CAD would be reasonable and could be an independent risk factor for CAD.
Fatemeh Dorreh, Parsa Yousefi, Javad Javaheri, Babak Eshrati, Zahra Amiri,
Volume 16, Issue 8 (11-2013)
Abstract
background: Early detection and treatment are crucial to prevent mental retardation in congenital Hypothyroidism (CH). The aim of this study was to evaluating of screening program of CH in Markazi Province.
Materials and Methods: In cross sectional descriptive study we used recorded data in Markazi province health center. From 2006 to 2012,127112 newborns were screened by measurement of serum TSH level by heel prick. Neonates who had blood TSH&ge5MIU/L were recalled for more evaluation. Neonates with confirmed hypothyroidism underwent treatment.
Results: From127112 screened neonates, 414 were diagnosed as CH patients (both permanent and transient). The prevalence of CH was . Recall rate was 4.8%. In 94.4% of patients, treatment were begun before the 40th day of life. The coverage percent in the province was 100% from the second year of the program.
Conclusion: Recall rate and the incidence of CH were higher than those in other studies, both in Iran and other countries. The mean age of treatment initiation and coverage percent were in favorable range.
Mojtaba Hashemi, Javad Javaheri, Marjan Habibi, Parsa Yousefi Chaijan, Mahdyieh Naziri,
Volume 18, Issue 6 (9-2015)
Abstract
Background: The prevalence of constipation in childhood is 0.7% to 29.6%. Inorganic causes are considered as the most common cause of constipation in children. Polyethylene glycol (PEG) is the most effective and safest laxatives which is usable in children in the long-term. This study was conducted to evaluate and compare the effect of PEG treatment and probiotic bacilluscoagulans and bifidobacterium and probiotic to enhance the growth of probiotics.
Materials and Methods: In this double blind clinical trial study(interventional study), 120 children aged 2-16 years with chronic functional constipation enrolled the study based on ROME III criteria. The bowels became empty by using liquid paraffin. Then, children were randomly divided into three groups of polyethylene glycol+placebo and Probiotics+placebo and polyethylene glycol+probiotics recipients. After 6 weeks of treatment, treatment success rates between the three groups were compared before and after the study Data analyzed by SPSS 20 software.
Results: The results of the study conducted on the three groups for treatment of constipation showed that the effect of polyethylene glycol and probiotic on treatment was considerable before and after treatment but the levels of effect was similar in the comparison of groups. The simultaneous use of two drugs was more effective than a single drug.
Conclusion: Overall, the results of our study showed that concurrent use of polyethylene glycol and probiotics is much more effective in the treatment of constipation.
Elnaz Abbasi, Javad Javaheri, Hamid Momeni, Ehsanollah Ghaznavi-Rad,
Volume 22, Issue 2 (6-2019)
Abstract
Background and Aim: Shigella species are one of the main causes of dysentery. This study aimed to determine the frequency and antibiotic resistance patterns of Shigella species isolated from infectious diarrhea samples in khomein, Iran.
Materials and Methods: A total of 54 infectious diarrhea samples obtained from patients were included in this descriptive cross-sectional study from June 2017 through November 2018. The infectious diarrhea samples were cultured to XLD, MacConkey agar and GN Broth. The phenotypic antibiotic resistance profiles were determined.
Ethical Considerations: This study with research ethics code IR.ARAKMU.REC.1396.307 has been approved by research ethics committee at Arak University of Medical Sciences.
Findings: Out of 54 infectious diarrhea samples, 11 (20.3%) with Shigella spp were identified using culture media. S. sonnei 9(81.8%) and S. flexneri 2(18.1%) were the single species found. The highest antibiotic resistance rates were found for cotrimoxazole 11(100%), ampicillin 10(90.9%), cefixime, cefotaxime and ceftriaxone 9(81.8%). In this study, 8 (72.7%) of the isolates were ESBL and 1 (9%) were AmpC positive.
Conclusion: This study showed that Shigell spp are the main bacterial agent causing dysentery in infectious diarrhea samples in khomein, Iran. This should be taken into consideration by infectious specialists especially during empirical treatment.
Mr Abbas Bayat Asghari, Mr Javad Javaheri, Mr Alireza Manzari Tavakoli, Mr Hamid Mollayi Zarandi,
Volume 25, Issue 6 (February & March 2023)
Abstract
Introduction: The purpose of this study was to compare the effectiveness of cognitive-behavioral therapy and motivational interviewing on self-esteem in divorced women.
Methods: The current study was a semi-experimental pre-test and post-test design. The statistical population consisted of 260 divorced women aged 20 to 50. 60 women were selected based on the inclusion criteria and randomly assign to three groups of cognitive-behavioral therapy, motivational interview therapy and control group. The instrument of data collection was Rosenberg Self- Esteem Questionnaire. For the experimental groups, 12 sessions of 75 minutes were held. No intervention was done for the control group. Before the interventions and at the end of the study, people in all groups filled out the questionnaire. The data was analyzed using SPSS version 25 software and analysis of covariance (ANCOVA).
Results: There was a significant difference between the three groups of cognitive-behavioral therapy, motivational interview and the control group in the comparison of the mean score of self-esteem variables (P<0.05). Also, in the one-by-one comparison of the cognitive-behavioral therapy and motivational interview therapy groups with the control group, there was a significant difference in the post-test stage (P<0.05).
Ethical considerations: In this research, the principle of confidentiality, preservation of personal information and non-disclosure of the identity of the participants were ensured and it was reminded that the obtained information will only be used statistically.
Conclusions: The findings indicate that cognitive-behavioral therapy and motivational interviewing are effective in enhancing self-esteem in divorced women. It suggests that these two methods are used along with other psychological and pharmaceutical therapies for divorced women as a clinical intervention.
