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Introduction: Opioids abuse is a nationwide problem in our country. Regarding the potential of these drugs in crossing placenta they can cause many defects in fetuses of human and also animals. In the present study, the effects of maternal Morphine consumption on olfactory bulb development in rats have been investigated. Materials and Methods: Female Wistar rats (weight: 250-300g) were crossed with male rats and the zero time of pregnancy was detected. Existence of vaginal plug and also sperm in vaginal smear were indicators of mating and pregnancy. Experimental group received 0.05 mg/ml of Morphine in drinking water daily. On embryonic day 19, pregnant animals were anesthetized by Chloroform and embryos were taken out surgically. Weight of the embryos was determined by a digital balance and their length (Crown-Rump, Frontal-Occipital, Biparietal, Abdominal-Transfer and Anterior-Posterior diameters) were determined by a caliper. Then embryos were fixed in Formalin 10% and tissues were processed and sectioned and stained in Hematoxilin & Eosin and Bielschwosky staining methods. These sections were investigated for olfactory bulb development by MOTIC software and light Microscope. Data was analyzed using t-test. Results: The decrease in embryonic weight and their diameter for experiment group was significant. In microscopic study, the increase in thickness of mitral layer and the decrease in total number of Tufted, Mitral and Granular cells in experimental group were significant. Conclusion: This study showed that oral Morphine consumption leads to olfactory bulb defects.

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Background: Epidemiological studies have shown the relationship between incidence of asthma symptoms and environmental factors, such as sedentary lifestyle and metabolic and cardiovascular diseases. However, the role of exercise rehabilitation protocols on lung function in obese adult patients with chronic asthma is a controversial issue. The aim of the present study is to evaluate the impact of aerobic exercise on lung function in obese middle-aged men with chronic asthma. Materials and Methods: This semi-experimental study was conducted on 39 obese middle-aged males with mild and moderate asthma. The experimental group (n=19) with regard to the safe range 15≥ RPE>9 followed the sub-maximal rehabilitation exercise program (50 to 80% HRmax intensity) for 3 months. Then, they underwent one month of detraining. The control group (n=20) did not have any form of aerobic exercise. Spirometric parameters in base, three months of training, and one month of detraining were measured by standard methods. Results: Indicators of lung function, including FVC, FEV1/FVC, PEF, FEF%75, and MVV significantly decreased. The pattern of changes in FEV1, FEV1/FVC, and MVV remained stable even after a month of detraining (p<0.05). However, no significant changes occurred in the dependent variables of the control group (p>0.05). Conclusion: It seems that the incidence of physiological adaptations of aerobic exercise, as a non-pharmacologic clinical factor, after the one-month detraining period affected the spirometric parameters in obese asthmatic patients

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Background: Determining the level of manual ability of children with cerebral palsy has significant role in scheduling care and providing supportive services by organizations such as the a social welfare office. Manual Ability Classification System (MACS) is responsible for this critical matter. In Mazandaran Province, the prediction of manual ability is intuitive and is done without tools. This study aimed to investigate the consistency between operational therapists prediction of future manual function of children with cerebral palsy and MACS scale.

Materials and Methods: This study was designed as a cross sectional trial. The study population consisted of 12 occupational therapists working in Mazandaran’s rehabilitation center under the social welfare office. Firstly, occupational therapists chose 100 children with cerebral palsy and classified their future manual ability into five levels according to their prediction. Then the researcher classified the children based on MACS scale. Finally, the amount of prediction consistency between therapists and researcher was statisticaly analyzed.

Results: The weighted kappa coefficients of MACS scale were 0.671 in first level and 0.747 in fifth level that show good agreement in these two levels. This coefficient was 0.417 in third level and 0.444 in forth level that shows fair agreement. The weighted kappa coefficient was 0.358 in second level that indicates slight agreement.

Conclusion: With prediction consistency between operational therapists and researcher, MACS is used as a suitable means for classifying the level of manual ability in children with cerebral palsy and predicting their needs to adaptive and auxiliary devices by occupational therapists in rehabilitation centers and social welfare offices.

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Introduction: Despite the adverse consequences of cesarean delivery, its incidence rate is increasing in many provinces of the country, especially Ilam city. For this reason, it is important to identify the causes of the increase in cesarean delivery in order to reduce it. Therefore, the present study was conducted with the aim of determining the frequency of cesarean section and its causes in primiparous women in Ilam city in 2016.
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Methodology: The present study was conducted cross-sectionally in the second half of 2016 in Ilam city, and the study population was all primiparous women referred to a single specialty maternity hospital (Ayatollah Taleghani Hospital). The sampling method was census and all cesarean deliveries were recorded in Ayatollah Taleghani Hospital. The inclusion criteria included all primiparous women. The data of the study was collected using a researcher-made questionnaire that included demographic and midwifery information. After collecting the data, the data was entered into the SPSS version 16 software Central indices were used to describe data in quantitative variables, and absolute and cumulative frequency and percentage of dispersion frequency were used for qualitative variables.
Findings: According to the findings of this study, out of 1738 births, 867 (49.88%) were natural births and 871 (50.12%) were cesarean. Among the natural births, 427 (49.25%) and among the cesarean births, 296 (33.98%) were primiparous. Among the maternal factors, lack of progress and among the fetal factors, fetal distress and among the maternal-fetal factors, head-to-pelvis disproportion was one of the most important causes of cesarean delivery in primiparous women. In general, fetal factors with more than 67% were the most important causes of caesarean section in primiparous women.

Conclusion: According to the findings of the study, 33.98% of cesarean births were primiparous. Considering the high statistics of caesarean section, especially cesarean section for first births , It is necessary to reduce the number of elective cesarean sections by increasing the number of physiological births and painless births, as well as increasing the awareness of families about birthing methods and the advantages and disadvantages of each of them.