Showing 7 results for Hatami
Shahla Enshaieh, Amir Hossein Siadat, Ali Asilian, Mohammad Ali Nilforoush-Zadeh , Fariba Iraji, Mohsen Khatami-Pour , Rezvan Fasih,
Volume 6, Issue 2 (Summer 2003)
Abstract
Introduction: Androgenetic alopecia is a very common disease. According to some reports, up to 96% of people have some form of this disease. In this paper we compared the effect of an herbal drug composed of the urticadioica, chamomilla, thymus vulgaris, equisetum arvense and foeniculum vulgare with 2% Minoxidil solution in the treatment of androgenetic alopecia.
Materials and Methods: We evaluated 82 patients suffering from androgenetic alopecia in a double blind prospective study. We counted terminal and vellous hair in 1 square centimeter of the predetermined area of scalp before and after treatment. After 6 months of treatment, the results were evaluated
Results: According to our findings, herbal drug and Minoxidil were effective in regrowthing the hair (45% vs. 35% respectively) and there were no meaningful differences between efficiacies of these two drugs
Conclusion: Herbal drug can be used as an adjunct or as an alternative to Minoxidil for treatment of the androgenetic alopecia.
Abolfazl Mozafari, Latif Moini, Shahram Arsang, Mahdi Gholamzadeh Baeis, Abbas Javid, Sam Hatami, Zahra Faraji, Bahareh Zareh,
Volume 17, Issue 9 (12-2014)
Abstract
Background: Despite control, prevention and the availability of drugs to cure tuberculosis, TB remains an important cause of death from an infectious agent in Iran. Pulmonary tuberculosis is more than 80% of tuberculosis cases. Chest x-ray is sensitive, cheap and accessible instrument for the diagnosis of tuberculosis. The aim of this study was to determine the radiological changes in patients with pulmonary tuberculosis.
Materials and Methods: In this cross-sectional study, after consideration of inclusion and exclusion criteria, finally 477 radiographic patients referred to rural and urban clinics in recent decade were enrolled. The affected lobe or lobes of the left or right lung were recorded. The types of involvement were categorized based on patchy consolidation, cavitation, fibrosis, bronchiectasis, gohn lesion, bronchogenic spread and bronchopneumonia. Pearson correlation coefficient was used to measure the strength of association between continuous variables. For analysis of qualitative parameters, we use from Chi-square test. Data analysis was done in SPSS18 and p value below than 0.05 was significant.
Results: Out of 477 patients, mean age was 48.24±22 years old, male including 33.3%, Iranian and urban cases were 44% and 91.3% respectively. The most frequent involved site was the left upper lobe followed by the right upper lobe. The most frequent radiographic finding was patchy consolidation and then bronchogenic spread and pneumonic consolidation respectively. There was significant correlation between lung cavities in patients with nationality.
Conclusion: This study could help to early diagnosis and treatment of suspect patients to pulmonary tuberculosis.
Ali Zakiei, Faramarz Morovati, Peyman Hatamian, Ashkan Bagheri, Delnia Sheik-Esmaeili,
Volume 20, Issue 10 (1-2018)
Abstract
Abstract
Background: Today, overweight is a damaging agent that threats general health and mental states. So, the current research was done with the aim of specifying the relationship between personality attributes (neuroticism, psychoticism), self-efficacy in weight control with people’s weight.
Materials and Methods: This was a descriptive - correlational study. The sample concluded of all of students in Razi university of Kermanshah in year 2015-2016; of them 459 people were selected with stochastic random sampling method. The research tools were self-efficacy of lifestyle that effects on weight and Eisenck personality questionnaires.
Results: The results showed that there is a negative significant relationship between weight with neuroticism and psychotics (p<0.001), but there was no significant relationship between neuroticism and weight. Also, the results showed that the components of self-efficacy in weight control can predict weight of people. Based on this, overeating with impact factor equal to 0.001, diet with 0.28 and oral inhibition with -0.13 of impact factor can predict weight of people.
Conclusion: Due to the results, psycho personality and self-efficacy have roles in weight control of people.
Mohammad Rahmanian, Ali Reza Kamali, Hadi Mosalanezhad, Mahdi Foroughian, Navid Kalani, Naser Hatami, Mohammad Heidarnezhad, Esmaeal Rayatdoost, Samaneh Abiri,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: The recent Coronavirus Disease 2019 (COVID-19) outbreak has caused a lot of stress and anxiety in the world. Given that health care workers are at the forefront of fighting against COVID-19, they are the first to be exposed to this disease.
Methods & Materials: This is a descriptive cross-sectional study conducted on 402 medical and administrative staff working in hospitals and health centers affiliated to Jahrom University of Medical Sciences in 2020. Data collection tools were a demographic form and the Corona Disease Anxiety Scale (CDAS).
Ethical Considerations: This study was approved by the Vice-Chancellor for Research of Jahrom University of Medical Sciences (Code: IR.JUMS.REC.1399.046).
Results: The mean score of psychological symptoms of anxiety in the medical staff (46.91) was higher than in the administrative staff (42.63). Its physical symptoms were also higher in the clinical staff (12.80) compared to the administrative staff (10.94). There was a significant difference between the clinical and administrative staff in terms of anxiety (P=0.030).
Conclusion: Medical staff has higher psychological and physical symptoms of anxiety compared to the non-medical staff during the COVID-19 outbreak. Therefore, in order to reduce the anxiety of medical staff, health policymakers should take the necessary measures to take care of this group.
Mohammad Rahmanian, Ali Reza Kamali, Mahdi Foroughian, Navid Kalani, Nafiseh Esmaealpour, Naser Hatami, Esmaeal Rayat Dost,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: The COVID-19 pandemic is capable of severely affecting the mental health of health care workers, who are at the forefront of this crisis; while the official staff of health organizations is facing the same danger. Therefore, monitoring awareness and other mental health issues to understand the mediating factors and awareness of appropriate interventions is a necessary priority. Therefore, the purpose of this study was to compare the level of knowledge, attitude, and practice of medical and administrative staff in facing the COVID-19 virus.
Methods & Materials: This cross-sectional descriptive study was performed on 160 medical and administrative staff of Jahrom hospitals in 2020. Demographic information questionnaire and researcher-made questionnaire of knowledge, attitude and practice of medical personnel about coronavirus (Covid 19) were used to collect information. Data were analyzed using SPSS software version 21 and descriptive and inferential statistical tests.
Results: 65% of subjects were women and the rest were men. In most of the answers given to each item in both groups, the medical and administrative staff’s answers were close to each other. In the case of the statement "I am more likely to get a corona", 54.4% of the medical staff chose the strongly agreed option, while this percentage is 16.5% for the administrative staff. This indicates that the medical staff is very afraid of getting COVID-19. According to the results, the mean knowledge scores of the medical staff (with an average of 94.35) were significantly higher than the administrative staff (with an average of 87.75) (t=5.96, p<0.001). But the performance of administrative staff (with an average of 93.14) is significantly higher than medical staff (with an average of 87.17) (t=-2.710, p=0.007). No significant difference was observed between the mean scores of the attitude scores of both groups (p=0.438).
Conclusion: The results of this study showed that the level of awareness in the face of corona virus in the administrative staff is significantly lower than the medical staff, but the administrative staff has a better performance in facing of the corona virus than the medical staff. It seems that educational measures are necessary to increase the awareness of these people.
Gholamreza Shookohi, Naser Hatami, Omid Mojarad, Ahmad Abolghazi,
Volume 25, Issue 3 (August & September 2022)
Abstract
Background and Aim Acanthamoeba is one of free-living amoebas, which are very abundant in nature. As a free-living amoeba, this parasite has a very high lethality, especially in people with underlying diseases, so researchers are always looking for a way to combat it. Drug plants are a good way to fight Acanthamoeba species. In this study, we aimed to investigate the lethal effect of the extract of Oliveria decumbens vent and Peganum harmala alcoholic extract on Acanthamoeba.
Methods & Materials In this study using the extract from an extract of Oliveria decumbens vent and Peganum harmala with concentrations of 1.25, 2.5, 5, 10, and 20 mg/ml to investigate the lethal effect of this extract. The plant was treated with Acanthamoeba amoebae after three times (24, 48, and 72) hours.
Ethical Considerations This study was approved by the Ethics Committee of the Jahrom University of Medical Sciences (Code: IR.JUMS.REC.1398.029).
Results The present research showed that using different concentrations at three times (24, 48, and 72) hours the effect of the extract on trophozoites and cysts of Acanthamoeba was shown. The highest lethality is related to the concentration of 20 mg/ml using a combination of both extracts at the time 72 hours and the lowest lethality is related to the concentration of 1.25 mg/ml of Oliveria decumbens vent at the time 24 hours.
Conclusion Observations indicate that the alcoholic extract of Oliveria decumbens vent and Peganum harmala had a perfect effect both separately and in a combination of both extracts. These two extracts had a synergistic effect on the lethal effect of Acanthamoeba amoeba.
Malihe Keykhapour, Javad Baharara, Hamed Hatami, Maryam Lotfi, Sajad Farrokhyar,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Harmine is an alkaloid from the carboline family, belonging to the harmal plant, which has extensive applications in traditional medicine, with numerous studies highlighting its anti-cancer effects. Since biological processes are influenced by electromagnetic fields, the current study examined the anti-cancer effects of harmine and low-frequency electromagnetic fields on the expression of COX2, VEGF, and MMP-2 genes in the A2780 cell line.
Methods: In this experimental-laboratory study, ovarian cancer cell lines were randomly divided into four groups: control, harmine at concentrations of 6, 12, 24, 48, 96, and 192 micromolar, low-frequency electromagnetic field with an intensity of 50 Gauss, and harmine at a concentration of 48 micromolar with a low-frequency electromagnetic field of 50 Gauss intensity. Their toxicity was assessed using the MTT assay, nuclear morphological changes by DAPI staining, apoptotic effects of these compounds by measuring nitric oxide (NO), and gene expression changes by Real-Time PCR. Quantitative data were analyzed the ANOVA statistical test at a P < 0.05 level.
Results: Quantitative data comparison of this research indicated that harmine and a low-frequency electromagnetic field with an intensity of 50 Gauss caused a concentration-dependent reduction in the viability of ovarian cancer cells. Additionally, in the nitric oxide test, a significant decrease was found in the control group compared to the groups treated with a concentration of 48 micromolar and synergized with a 50 Gauss electromagnetic field (p<0.05). The expression of the aforementioned genes in treated cells showed a significant decrease. Treating ovarian cancer cells with harmine and its combined application led to significant nuclear morphological changes, including chromatin condensation, formation of apoptotic bodies, and wrinkling of the cell membrane.
Conclusions: The combined application of harmine and a low-frequency electromagnetic field induced apoptosis in A2780 cancer cells and resulted in the downregulation of COX2, VEGF-A, and MMP-2 gene expression. Consequently, the combined use of harmine with a low-frequency electromagnetic field, due to its effective cytotoxicity in inhibiting proliferation and inducing apoptosis, could be a suitable candidate for clinical studies.
