Showing 13 results for Ghanbari
Ali Ghanbari, Behrooz Nicknafs, Taghi Taghi Al-Tarihi,
Volume 4, Issue 3 (Autumn 2001)
Abstract
Introduction: One of the methods of cancer treatment is use of chemotherapic drugs. Breast cancer is a common desease that chemotherapic drugs have not treated it yet. In this research, Cell proliferation inhibition in MCF-7 cells, a human breast carcinoma cell line , after treatment with Cisplatin, an anticancer drug is studied.
Material and Method: At first, after cell counting with trypan blue stain, equal cells were added to flasks and flasks were divided in to two control and experimental groups. In experimental group, 1 micro mole cisplatin exposure in 1 hour, where control group with normal saline solution. after that, flasks were incubated for 48 hours. After passing this time, attached cells of two control and experimental groups, were stained with trypan blue for cell counting and with toloiden blue for light microscopy individually. Obtained results were divided into two section, cell counting and light microscopy. In cell counting. Obtained results were evaluated with Mann-Withney Statistical test.
Results: results showed that number of attached cells in experimental group was reduced. In light microscopy, morphological features of attached MCF-7 cells in two groups were similar.
Conclusion: Through that, attached MCF-7 cells are proliferating so we can say that without altering in Morphological features, Cisplatin causes inhibition in cell proliferation of MCF-7 cells.
Akram Bayati, Fatemeh Ghanbari, Mohsen Shamsi,
Volume 15, Issue 10 (March 2013)
Abstract
Background: Considering the importance of the presence of volunteer health care communicators and the reduction in their cooperation with health centers or their breaking off their communication in recent years, this study was done to explore the educational needs of health care communicators and their instructors. Materials and Methods: In a qualitative study, data were obtained through focus group discussions (FGDs) and individual depth interviews (IDIs) for need assessment from three groups of active volunteer health care workers, inactive volunteer health care workers and health instructors. In total, 14 FGD and 5 DII were held to cover the aims of research chosen by aimed sampling. The analysis was carried out by qualitative content analysis. Results: Three major themes emerged from data analysis, including the concepts of soft and hard tools (time, space, educational tools, and educational content), educator (teaching methods, awareness, and skills), and learner (application, literacy, experience learning level, and motivation). Conclusion: Many of the educational needs of the health care communicators and their educators had not been met which, in many cases, had led to the discontinuation of their cooperation with health centers. Hence, presenting the obtained feedback to officials for meeting their needs can be an effective measure in improving the activities of the communicators and their continuous presence in the health care system.
Mahbobe Khaton Ghanbari, Mohsen Shamsi, Ali Asghar Farazi, Mahbobe Khorsandii, Babak Eshrati,
Volume 16, Issue 7 (10-2013)
Abstract
Background: Survey and control of nosocomial infections in the world is a global priority that The objective is to minimize infections in addition to decreased length of hospitalization And also significantly reduce the cost of health care .The aim of this study was evaluating the knowledge, self-efficacy and Practice of nursing staff in Disciplines Standard Precautions in order to prevention of nosocomial infection.
Materials and Methods: This Cross-sectional and analytical study that was carried out on 130nursing staff selectedin in Arak university of medical sciense in 2013. Data collected with validity and reliebility questionnaire including of knowledge, self-efficacy and Practice of nursing staff in Disciplines Standard Precautions in order to prevention of nosocomial infection. Data was analyzed by using descriptive and analytical statistical methods and pearson correlation.
Results: The mean knowledge was 46.92±14.66 and Practice 49.46±6.96 and average self-efficacy was 52.2±10.81 about infection prevention. There was not significant relationship between knowledge and Practice. But there was a significant relationship between self-efficacy, knowledge and Practice and marriage. Moreover there was a significant relationship between knowledge and gender. (p<0.05).
Conclusion: Despite moderate self-efficacy majority of Nurses do not have appropriate knowledge about prevention of nosocomial infection based on the findings of this study. Considering the important role of nurses in nosocomial infection prevention, training is necessary to increase nurses prevention behaviors. Therefor paying more attention by authorities to apply the necessary actions for training of nurses.
Akram Bayati, Fatemeh Ghanbari, Akram Maleki, Seyyed Shahriar Hoseini, Mohsen Shamsi,
Volume 17, Issue 1 (4-2014)
Abstract
Background: One of the amendments made in Iran's Health System was family physician program were introduced in 2004 . This study aimed to describe the experiences of physician and other health team members about general interest of this program.
Materiasl and Methods: This study is a qualitative and data collection method was in-depth interviews (semi-structured). Groups participants including 15 physicians, 15 midwives and 25 healthworker declare their experiences about of general advantage in this program. In total, 55 interviews were carried out in population. Purposive sampling fand content analysis with comparative of the methods were used.
Results: In this study, after continuous analysis of data 376 initial codes were obtained. After integration of theses codes 30 the secondary cods come out which consist of public or general interest and economic benefit, respectively. Moreover 4 sub-categories (improve of index of public health and care, health folder, insurance for rural, low referral to expert of physican), were created.
Conclusion: Based on the results the use of electronic folders instead of traditional folder and accelerate to acsess of information patient for promotion of care and finally delivery some facilitate for health team worker recommended.
Mohammad Reza Massoudinejad, Ashraf Mazaheri Tehrani, Farshid Ghanbari, Simindokht Mirshafian,
Volume 17, Issue 3 (6-2014)
Abstract
Background: The conventional methods of water disinfection are chemical process, ozonation, UV radiation, membrane processes and etc. In recent years, electrolysis method has been considered that is a green process with high efficiency and not by-products. The aim of study is evaluation of efficiency of the electrolysis process with continuous flow in the disinfection of water contaminated with fecal coliform.
Materials and Methods: This study is a Descriptive - analytical study. The samples are prepared in three groups by adding domestic wastewater, manure and E.Coli colonies to distilled water. The prepared samples were introduced to continuous electrochemical reactor. The removal efficiency of electrolysis process was investigated in different conditions which include electrode material (copper and graphite compressed), reaction time (40, 50, 60 and 70 minutes), voltage 48V, distance of electrode 5 cm and the initial pH 7.
Results: The results indicate that removal efficiency depends on source of pollutant, reaction time, and type of electrode. Also the optimal efficiency for E.Coli colonies achieved in electrolysis instrument was as follows: electrode material = copper electrode, distance of electrode=5cm, applied voltage= 48V and reaction time=70 minute. Under these conditions removal efficiency was obtained 99%. No significant changes in pH, TDS and EC in different times and coliform bacteria were not created by changing the source.
Conclusion: According to the results of this study, using the electrolysis process with continuous flow, as a convenient method with high performance and environmentally, suggest for the disin fecting the water contaminated with fecal Coliform.
Zeinab Hameidi Zad, Saeed Hajihashemi, Ali Rahbari, Fatemeh Ghanbari,
Volume 19, Issue 7 (10-2016)
Abstract
Background: Gentamicin (GM) is one the aminoglycoside antibiotics which isroutinelyused to treatinfections gram-negative, either alone or insynergistic withbeta-lactamantibioticsused. However, frequent useleads toserious side effectssuch asrenal toxicity, ototoxicity. Coenzyme Q10 has antioxidant, anti-inflammatory and vasodilatory properties. According to these properties of Coenzyme Q10 and tissue damage mechanism in GM induced-nephrotoxicity, in this study, the effects of these two substances for the co-treatment and post -treatment on renal injury induced by gentamicin were investigated.
Materials and Methods: Experiments has been done on 77 male Wistar rats in weight range of 200 to 250 g. Animals were divided randomly into 5 groups of 7 numbers. Renal nephrotoxicity induced by i.p injection of gentamicin (100mg/kg) Therapeutic effect of coenzyme Q10 (10mg/kg)in the two protocols co-treatment and post-treatmentwas investigated.The animals after the last injectionon the ninth day of co-treatment andthe seventeenth day of post-treatmentwere placed into individual metabolic cages so as to collection urine and urine volume was measured gravimetrically. Afteranesthesia, systolic blood pressure and renal blood flow was measured. Then blood sampling was done. Amount of urea, creatinin, sodium, potassium and osmolarity was measured in plasma and urine samples. Left kidney, for doing histological experiments in 10% buffered formaldehyde and right kidney for biochemical experiments in fluid nitrogen was preserved.
Results: Co-treatment with Coenzyme Q10 significantly decreased fractional excretion of sodium (6.37±1.33 %; p<0.001) and decreased fractional excretion of potassium(219.14±83.8 %; p<0.001) MDA levels (2.13 ±0.24µmol/gkw; p<0.001), and significantly increased renal blood flow (6.38 ±0.1ml/min: p<0.01) and FRAP levels (24.44±0.42mmol/gkw; p<0.001). Post-treatment with coenzyme Q10 significantly decreased fractional excretion of sodium (3.58 ±0.57 %; p<0.001), potassium (111.77±29.4%; p<0.001) and MDA levels (3.08 ±0.12µmol/gkw; p<0.001) and significantly increased renal blood flow (6.74±0.15ml/min: p<0.001) and FRAP levels (24.34±0.75mmol/gkw; p<0.001) that is reduced by gentamicin.
Conclusion: According to the results, this study showed thatpost- treatment with coenzyme Q10more protective effect on the kidney tissue andAnda greater increase inantioxidant defensecreated.
Mojtaba Habibi, Nikzad Ghanbari, Moloud Sivandian, Hanieh Mahdizadeh Hanjani,
Volume 21, Issue 5 (10-2018)
Abstract
Background and Aim: Present study was conducted to investigate the prediction of juvenile delinquency based on individual vulnerability and the risk opportunity in the family, peers, school and neighborhood in high schools in Tehran
Materials and Methods: This is a coss-sectional study. The statistical population of this study included all the female and male students of 20 districts of Tehran who were studying in high school during the academic year 2013-2014. The sample size of the study was 1847 individuals (946 (51.2%) girls and 901 (48.8%) boys). The sampling was performed in a multi-stage cluster method due to the extent of the population, and the participants of this study completed the socio-mental protective and risk factors and behaviors scale. Data were analyzed using multiple regression analysis, stepwise method, and SPSS-24 statistical software.
Findings: Results of present study showed that among predictor variables, risk opportunity/availability (B=0.67, t=13.28, p<0.001), vulnerability/family (B=0.37, t=8.57, p<0.001), and vulnerability/school (B=1.14, t=6.7, p<0.001) have significant prediction effect on adjusted index of adolescents’ delinquent behavior, also adolescent boys do more delinquent behavior than girls (t (1823) =4.82, p<0. 01).
Conclusion: This study showed that the individual vulnerability and risk opportunity in the family, peers, school and neighborhood predict delinquent behavior in adolescents. So, it is necessary to take preventive measures and interventions for this age group, risk factors should be considered at individual, school and family levels.
Behrooz Ghanbari, Mojtaba Hedayat Taghavi, Behamin Astani, Mahmoud Bakhtiari, Mohsen Yadegari, Yazdan Shafikhani,
Volume 26, Issue 0 (8-2023)
Abstract
Abstract:
Background
CAP ( community acquired pneumonia ) is one of the most common infectious diseases that leads to hospitalization of patients. Also, the effects of vitamin D deficiency on the functioning of the immune system and its association with infectious diseases such as CAP have received much attention in recent years. Therefore, we decided to investigate the relationship between serum vitamin D levels and the incidence and severity of CAP pneumonia in this study.
Methods
In this case-control study, 75 patients with CAP and 75 healthy individuals were evaluated and serum levels of vitamin D in these two groups were measured and compared.
Results
The present study shows that for each unit increase in serum vitamin D level, the need for hospitalization in the ICU according to the IDSA criterion is reduced by seven percent and according to the CURB65 criterion, the need for hospitalization in the ward and ICU is reduced by fifteen percent. Vitamin D deficiency also increases the chance of developing community-acquired pneumonia by 3.08 times. And for every unit increase in vitamin D, the chance of developing community-acquired pneumonia decreases by 4 percent. And in people with vitamin D deficiency, the chance of being admitted to the ICU according to IDSA is 2.05 times and according to CURB65 is 2.84 times.
Conclusions
Overall, based on the results of this study, it is concluded that vitamin D deficiency is associated with an increased incidence as well as a greater severity of community acquired pneumonia.
Dr Zahra Ghanbari,
Volume 26, Issue 5 (December & January 2023)
Abstract
Introduction: The purpose of this research was to investigate the effectiveness of family therapy based on family consolidation on marital conflicts and sexual satisfaction of couples applying for divorce.
Methods: The research method was semi-experimental with experimental and control groups. The statistical population of this research included all couples applying for divorce who referred to counseling centers in Kerman city in 2023. 30 couples were selected as available and were replaced in two experimental (15 couples) and control (15 couples) groups randomly and by lottery method. Family therapy intervention based on family consolidation was conducted in 8 sessions twice a week for 90 minutes and after 3 months of follow-up. In order to collect data, Barati and Sanai's Marital Conflict Questionnaire and Larson's Sexual Satisfaction Questionnaire were used. In order to analyze the data, descriptive statistics tests (mean and standard deviation) and analysis of variance with repeated measurements were used with SPSS version 24 software.
Results: The results showed that family therapy based on family consolidation had an effect on reducing marital conflicts (P < 0.001, F = 37.24) and increasing sexual satisfaction (P < 0.001, F = 126.34) of couples applying for divorce (P < 0.001).
Conclusions: According to the results of this research, it is recommended to use family therapy based on family consolidation in reducing marital conflicts and increasing sexual satisfaction of couples applying for divorce.
Ms Parnian Hekmatpou, Maryam Maryam Ghanbari, Milad Gholami,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: Gestational diabetes is defined as hyperglycemia with onset or first diagnosis during pregnancy, with a lower frequency than general diabetes. Overweight and obesity, old age at the time of pregnancy, previous history of gestational diabetes, family history of type 2 diabetes, and race are risk factors for gestational diabetes. Recently, the relationship between two polymorphisms (rs9939609 and rs1421085) of Fat mass and obesity-associated (FTO) gene and the risk of gestational diabetes has been investigated in some studies with conflicting results. Therefore, our aim of the present study was to investigate the association study of rs1421085 and rs9939609 of the FTO gene on gestational diabetes.
Methods: In this case-control study, five cc of peripheral blood was collected from 100 cases with gestational diabetes and 116 control pregnant women from Taleghani Hospital in Arak, and then DNA was extracted. After designing the specific primers, the genotypes were determined by the Tetra ARMS-PCR method. Demographic information was compared with genotypes between the two groups were compared using SNPSTAT software.
Results: A significant correlation was observed between obesity, BMI before and during pregnancy, HbA1c, FBS, cholesterol, and triglyceride levels among mothers with gestational diabetes compared to healthy pregnant mothers P = 0.0001. According to data analysis, there was no significant association between rs1421085 and rs9939609 of the FTO gene with gestational diabetes.
Conclusions: Considering the conflicting results between the association of FTO gene polymorphisms with gestational diabetes, to better identify and understand the pathogenesis of the disease, more studies with a higher number of samples and more racial groups are needed. In the future, identifying the profile and locations of genetic susceptibility to gestational diabetes can be used in the patient's management.
Saman Afrasiabi, Mahdi Goudarzvand, Amir Saeid Sedighi, Yazdan Shafikhani, Behrooz Ghanbari,
Volume 27, Issue 1 (3-2024)
Abstract
Introduction: Sequential word learning is a crucial aspect of memory research in cognitive neuroscience, emphasizing the importance of recalling words at the beginning (primacy) and end (recency) of a sequence. This study aims to investigate the extent of primacy and recency effects in patients with neglect syndrome caused by right parietal lobe damage.
Methods: This case-control study involved 18 patients with parietal lobe tumors, divided into two groups: 9 patients with neglect syndrome and nine without. Patients referred to the neurosurgery department of Shahid Tajrish Hospital with right parietal lobe lesions underwent neurological and psychological evaluations, including the cancellation test, line bisection test, copying test, and the 5-point test. Those diagnosed with neglect syndrome formed the syndrome group, while the rest constituted the control group. Both groups participated in immediate recall (short-term memory) and delayed recall (long-term memory) tests for sequential word learning, with results analyzed for primacy and recency effects.
Results: Among the 18 patients, 61% were men and 39% were women. Analysis of immediate and short-term memory tests for sequential word learning revealed no significant differences in primacy and recency effects between the two groups.
Conclusions: The findings suggest that patients with right parietal lobe damage and neglect syndrome do not exhibit significant differences in primacy or recency effects in verbal memory during sequential word learning compared to the control group. Consequently, immediate and short-term memory appears relatively unaffected in these patients.
Zahra Ghanbari Zarandi,
Volume 27, Issue 3 (7-2024)
Abstract
Introduction: Breast cancer causes psychological problems and decreases psychological health in people, therapeutic interventions are needed to solve these problems. This research was conducted to determine the effectiveness of group meaning therapy intervention on the quality of life, emotional regulation, and life expectancy of women with breast cancer.
Methods: The research method was semi-experimental with a pre-test-post-test design with a control group. The statistical population included all women with breast cancer referring to the health centers of Kerman city in 2023. Among them, 30 people were selected by the available sampling method and were replaced randomly and by lottery in two experimental and control groups (15 individuals in the experimental group and 15 in the control group). The people in the experimental group received group-meaning therapy intervention (10 sessions) and two sessions weekly for 90 minutes. The questionnaires used in this research included quality of life, emotion regulation, and life expectancy questionnaires administered in two phases: pre-test and post-test.
Results: The results showed that before the intervention, there was no significant difference between the average scores of the quality of life, emotion regulation, and life expectancy of the intervention and control groups, but there was a statistically significant difference between the average scores of the intervention and control groups after the intervention. The mean and standard deviation of the quality of life in the post-test was 6.91 ± 29.75, emotion regulation was 10.25 ± 98.28, and life expectancy was 6.49 ± 39.51 (P < 0.001).
Conclusions: According to the results of this research, group therapy increased the quality of life, emotion regulation, and life expectancy in women with cancer. Since the favorable mental state of the patient affects their recovery, the use of this method is recommended as an effective strategy to reduce the psychological problems of patients.
Leila Ghanbari-Afra, Mina Gaeeni, Jafar Shahbazpour,
Volume 27, Issue 4 (10-2024)
Abstract
Introduction: The fundamental role of marital satisfaction is vital in family formation and marriage survival. Marital dissatisfaction can make couples fail to solve their conflicts. Marital discontent, combined with job-related stress such as pre-hospital emergencies, can lead to heightened conflict in job responsibilities. It leads to the effect on personnel, patients, and their families. Therefore, this study aimed to investigate the marital satisfaction of pre-hospital emergency personnel at Qom University of Medical Sciences in 2023.
Methods: This cross-sectional study was conducted on 200 pre-hospital personnel of Qom University of Medical Sciences in May 2023. The sampling method was a stratified cluster. The data collection tool included the "Demographic Information" checklist and Enrich's "Marital Satisfaction" questionnaire. Data analysis was done using descriptive tests, Independent T-test, and Regression.
Results: The average age of the participants was 37.3 ± 7.06. More than half of the participants had a bachelor's degree. Most people had rotating shifts. The average score of marital satisfaction was 145.94 ± 22.21. Based on the results of the multivariate regression test, the variables of education, employment status, work experience, type of shift, having a second job, and having a job other than medical staff explain 63% of the variance of marital satisfaction of pre-hospital personnel.
Conclusions: According to the findings of the present study, in general, the marital satisfaction of pre-hospital emergency personnel of Qom University of Medical Sciences is at an average to high level. People with a fixed shift, with a second job, high work experience, without a fixed job status, and bachelor's and associate's degrees had less marital satisfaction than others. Therefore, managers and policymakers in the health field must pay more attention to the quality of family life, especially the married life of pre-hospital emergency workers with the mentioned conditions.
