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Introduction:Hyperlipidemia is one of the major risk factors of cardiovascular diseases. This study was done to assess lipid profiles according to sex and place of residence in the urban and rural area of Arak for controlling cardiovascular diseases. Materials and Methods:This descriptive study is the first phase of healthy heart program which was done in Arak. Sampling was randomized cluster. A questionnaire was used to collect demographic data and paraclinical test results (total cholesterol, LDL-c, HDL-c ,and Triglyceride). Data was analyzed using T-student, Kolmogorov-Smirnov, Mann-Whitney and Chi-square tests. Results: Of 4303 individuals over 30 years, 51.6% were female. Total cholesterol, LDL-c and HDL-c disturbances were more in female (p<0.05) but there was not a sigmifiant difference between male and female in triglyceride disturbance. The increase in serum lipids was signfiantly different in urban and rural areas, in which total cholesterol and LDL-c disturbances were more in rural and triglyceride disturbance was more in urban areas (p<0.0001). Conclusion: High prevalence of dyslipidemia in the studied region can be related to unhealthy life style, nutrition and inadequate physical activity, so dyslipidemia and cadiovascular diseases could be decreased by changing lifestyle.

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Background: Mental health is an important aspect of health and the World Health Organization defines health as "full physical, mental and social welfare, and not merely the absence of disease". Given that 79 percent of the health education focused on physical aspects, in fact, the most focus is on biological parameters of people to measure their health. So we need a valid questionnaire to measure mentally and physically the health of people in the research community.

Materials and Methods: The Holistic Wellness Model reflects that the researches is done on health which is different in variant cultures perspectives.102 managers and officials of Islamic Azad University of Arak participated in this studyin 2014 and the validity and reliability of the questionnaire were analyzed using the software SPSS20.

Results: 102 people were enrolled in this study, 74 males (72.5%) and the rest were female. Cronbach' Alpha coefficient for the entire questionnaire was 0.93.In all six aspects which reviewed, the correlation between all questions and its perspective was measured by using Spearman test. There was a significant positive correlation among all the questions and the related aspects.

Conclusion: The Persian version of physical and mental health questionnaire, based on the Holistic Wellness Model, is suitable to assess the health of people. Also, validity and reliability is appropriate.

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Background and Aim: Ovarian cancer is among the most common cancers in women worldwide. CA125 is the most frequent biomarker used in the screening for ovarian cancer. CA125 has no high sensitivity and specificity as a screening test in the medical community; however, because of being simple and noninvasive, it is almost always requested for evaluation and ruling out cancer. It plays an important role in the treatment and post-treatment process, the prediction of prognosis, and the relapse of the disease. The present study aimed to determine the relationship between a high level of CA125 tumor marker and ovarian cancer by detecting spesivity, sensivity, positive and negative predictive values.
Methods & Materials: In this cross-sectional study, all cases undergoing CA125 test in Velayat Hospital in 
2017-1028 were evaluated for having ovarian cancer. In addition, the CA125 level was compared between healthy individuals and patients with ovarian cancer. Finally, the obtained data were analyzed using SPSS.
Ethical Considerations: The present study was approved by the Qazvin University of Medical Sciences (Ethics Code: IR.QUMS.REC.1396.316).
Results: In this study, 35.3% of the study participants received a definite diagnosis of ovarian cancer. Generally, CA125 values were negative in 41.8% and positive in.58.2% of the study subjects. The sensitivity of the test was measured as 80.1%, the specivity as 53.6%, the positive predictive value equaled 48.4%, and the negative predictive value was measured as 83%. There was a significant relationship between age and the presence of ovarian cancer, and serum CA125 levels.
Conclusion: The present study suggested that age and the serum level of CA125 were statistically significant. Finally, CA125 levels were significantly related to ovarian cancer. It provided moderate specivity and specivity as well as low positive predictive value and high negative predictive value as a tumor marker; it is valuable for ruling out of tumor but not appropriate as a screening test.