Showing 5 results for Emam
Arash Bayat, Mohammad Farhadi, Hesamodin Emam Jomeh ,
Volume 6, Issue 1 (Spring 2003)
Abstract
Introduction: The existence of acoustic trauma secondary to drill noise during chronic ear surgeries has not yet been clearly demonestrated. This investigation aims to document the hearing loss that occures in patients who underwent mastoidectomy.
Materials and Methods: Sixty-three (38 male and 25 female) consecutive patients (11-57 years) who underwent modified radical mastoidectomy were included. In a concurrent clinical trial design, we measured bone conduction thresholds before and after (1 week and 1 month) operation on both sides.
Bone conduction thresholds were assessed in 250, 500, 1000, 2000, 3000 and 4000 Hz frequencies.
Results: Paired-test results showed a satistically significant temporary (TTS) and permanent threshold shifts (PTS) were occured in the 2000-4000 Hz region for operated (on addition to 1000 Hz) and non-operated ears, but clinically PTSs were not remarkable and TTSs were important only for operated ear (P<0.05). The correlation between duration of noise exposure and magnitude of threshold shift was only significant in operated ear in 2000-4000 Hz region (P<0.05).
Conclusion: We could not demonestrate any permanent hearing loss caused by drill-generated noise, but resultant noise is able to produce TTS in the operated ear in 2000-4000 Hz region. We found poor relationship between duration of noise exposure and magnitude of threshold shifts.
Mohammad Mehdi Emam, Sahba Chehreii, Ali Chehreii,
Volume 9, Issue 3 (9-2006)
Abstract
Introduction: Bone mineral density (BMD) measured by dual energy x-ray absorbtiometry (DEXA) is widely used in management of patients with osteoporosis. Factors which are specific to machine or operator, can influence the accuracy and precision of BMD estimations. In this study we investigated the effect of leg rotation and femoral neck on densitometry of femur. Materials and Methods: In a before and after, interventional study on 200 women between 30-70 years old, without metabolic bone diseases, densitometry was done first in standard position and then in 15ْ rotation of leg from standard position and then after changing femoral neck angle from 90ه to 80ْ in relation to central femoral neck axis . Density of femoral neck, ward triangle, greater trochanter, shaft of femur and total hip was measured and data was analyzed by means comparison test. Results: External rotation of leg by 15 ه from the customary position, increased the average BMD in femoral neck, wards area, trochanter and shaft (p<0.001, p<0.04, p<0.001, p<0.008 respectively).While no significant change was observed in average BMD of total hip. Change of femoral neck area angle from 90 ه to 80 ه in relation to central femoral axis decreased BMD in femoral neck (p<0.001), and significantly increased BMD in wards triangle, trochanter, shaft and total hip (p<0.001, p<0.001, p<0.001, p<0.04 respectively). Conclusion: Malrotation of hip can be an important confounding factor when interpreting serial BMD values. Regarding the less effect of malpositioning on BMD of total hip, this area may be prefered for assessment of densitometry result.
Seyede Faranak Emami,
Volume 18, Issue 10 (1-2016)
Abstract
Background: Saccule is part of the vestibular organ that is responsible for balancing the linear acceleration saccular can be evaluated performance by cervical vestibular evoked myogenic potentials (cVEMPs). This study aimed to determine the relationship between time delay and amplitude of the waves of cVEMPs with auditory training in deaf children of primary school age group of Hamadan in autumn 2014.
Materials and Methods: In this comparative cross-sectional study, the case group were children with profound hearing loss received six months of regular auditory training (n=20). The control group of children with profound hearing loss had no history of auditory training (n=20). Both of groups were evaluated by cVEMPs test.
Results: T-test between the two groups showed no significant difference in the time delays of waves p13 and n23 (p = 0.15, f = 18.58 and p = 0.20, f = 23.32, respectively). However, the difference of the peak-to-peak amplitude of waves p13-n23 was significant (p = 0.00, f = 10.13).
Conclusion: Voice vocalization and more experience of hearing can strengthen the saccular performance.
Pegah Parvaee, Mahdieh Mondanizadeh, Behzad Khansarinejad, Amir Nader Emami Razavi,
Volume 19, Issue 5 (8-2016)
Abstract
Background: Circulating microRNAs are promising biomarkers in diagnosis and assessment of cancerous patients. Quantitative Real-time PCR assay is a sensitive test for evaluating the levels of miRNAs expression. Nevertheless, there is no concurrence on selecting appropriate reference genes for qPCR analysis of miRNAs in circulation. Therefore, the current study aimed to select a suitable reference gene for normalizing the RT-qPCR assay results in plasma samples of patients with gastric cancer.
Materials and Methods: Based on previously published studies, three molecules SNORD47, U6 RNA, and miR-103 were selected as the candidate reference genes. After RNA extraction from plasma samples of 40 patients with gastric cancer and 40 healthy individuals, expression levels of these molecules were evaluated using Real-time PCR method.
Results: The results showed that the developed assays are able to diagnose their specified targets by a suitable linear range. By comparing patients and control groups, although the expression levels of miR-103 molecule were not equal between the two groups (p= 0.017), SNORD47 and U6 RNAs had similar expression levels. However, the variations of SNORD47 expression were lower that U6 RNA.
Conclusion: Based on the results of the current study, the SNORD47 molecule has a stable expression levels in plasma samples of patients with gastric cancer and normal individuals and can be used as an appropriate reference gene for normalizing the quantitative data of qPCR assay.
Ali Reza Morad Abadi, Mohammad Arjomandzadegan, Navid Emami, Manijeh Kahbazi, Azam Ahmadi, Saeed Falahat, Seyyed Hossein Hosseini, Mehdi Kargaran, Parisa Khosravi,
Volume 21, Issue 4 (8-2018)
Abstract
Background and Aim: Ziehl Nelson staining, fluorescent and also culture are the standard methods for the diagnosis of tuberculosis. In this study, the performance of conventional cultivation methods was compared with Flash PCR.
Materials and Methods: A total of 56 sputum samples from patients with suspected tuberculosis in Tuberculosis Center of Arak city were collected and Ziehl–Neelsen and culture in Löwenstein–Jensen medium were accomplished. Moreover, DNA from all of the 56 sputum samples was extracted by Chelex100 method. Molecular evaluation was accomplished by Flash PCR kit containing probes and primers for gene amplification IS6110. Positive and negative controls together with samples were used in a MTC410 apparatus for amplification. FD-12 apparatus was used to evaluate the results. In addition, electrophoresis on agarose was used for confirmation of the results.
Findings: From 56 sputum samples of suspected TB patients, 20 samples were positive and 36 samples were negative on microscopic evaluation and culture methods. FLASH-PCR molecular analysis showed that all of 20 positive samples were positive in molecular methods, too. On the other hand, three of sputum samples that were negative by culture and staining were positive in FLASH-PCR method. One of these 3 patients, received Isoniazid, pyrazinamide and ethambutol antibiotic by responsible medicine. All results were confirmed using conventional electrophoresis.
Conclusion: In some negative samples, possibly because of the small number of bacteria in sample or a defect in the sampling, the Flash PCR may due good advantages. Therefore, due to the low cost, this method is recommended for routine use.
