Showing 6 results for Eghbal
Rahmat Alah Jadidi, Davod Hekmatpou, Aziz Eghbali, Fereshteh Memari,
Volume 15, Issue 9 (February 2013)
Abstract
Background: Leukemia, due to its widespread prevalence, high mortality rate, high treatment expenses, and long hospital stay, influences the families and their children to a great extent. This study was done to explore the experiences of parents whose children suffer from leukemia. Materials and Methods: Using qualitative research approach with applying content analysis method, 22 participants were interviewed in two teaching hospitals during 2 months. The study started by purposive sampling and continued by a theoretical one till data saturation. The obtained data were constantly analyzed through content analysis method. Results: Data analysis showed that “finding no solution in life, having a lot of problems, errors in treatment, concealing the illness, faith in God, parents’ devotion, hospital facilities, and consistency were the level 3 codes of parents’ experiences and “parents’ reaching a dead-end in life” was the main theme or core category of this study. Conclusion: Using a qualitative approach for exploring the experiences of parents with a child suffering from blood cancer helped recognize them more profoundly than quantitative methods. On the other hand, “parents’ reaching a dead-end in life” as the theme shows the importance of attention to parents’ problems. Using these experiences can increase hope among parents and help conduct the treatment more effectively.
Aziz Eghbali, Afsaneh Akhondzadeh, Mohammad Rafiee, Fatemeh Dorreh,
Volume 16, Issue 4 (7-2013)
Abstract
Background: Osteopenia is a common and sometimes disabling consequence of the treatment of common neoplastic diseases, such as acute lymphoblastic leukemia (ALL) and lymphoma in children. The aim of the present study was to evaluate the preventing effects of alendronate on steroid-induced osteopenia in children with ALL and non- Hodgkin’s lymphoma (NHL).
Materials and Methods: In this clinical trial, 30 children with ALL and NHL were purposefully selected. All patients received the same induction chemotherapy protocol. Then they were randomly divided into two matched groups. All of them received equivalent supplement of 400 IU/d vitamin D and 30-40mg/kg/d calcium. The patients of the case group received 35mg/week alendronate for 6 months as well. Lumbar spine and whole body bone densitometry were performd before and after intervention and Z score was calculated for all patients.
Results: The mean age of the studied population was 6.11(±3.36) years and 15 of the children (50%) were male. There was no statistically significant difference in lumbar spine and whole body bone densitometry and Z score before and after intervention between the two groups (p>0.05). The improvement of bone densitometry and Z score were seen in both groups after intervention which was more in the case group but it was not statistically significant (p>0.05).
Conclusion: Administration of 35 mg/week alendronate for 6 months does not cause significant improvements in bone densitometry variables in children with ALL and NHL.
Farid Eghbali, Mahdi Moradi,
Volume 19, Issue 11 (2-2017)
Abstract
Background: High blood pressure increases various cardiovascular events about 2 to 3 times in a person. The purpose of this study is to recognize the effect of a course of pilates exercise on hypertension, nitric oxide, and resting heart rate in the eldrlymen with hypertension.
Materials and Methods: Subjects of this quasi-experimental research included 30 elderly men with hypertension grade one(in the range of systolic-diastolic 140/90 to 159/99mm Hg) who participated voluntarily and accessibly in the study and were divided randomly into two experimental peer (15 people) and control (15 people) groups. Weight, height and BMI of subjects were 75±80, 170±175 and 25-26, respectively. The experimental group did selected exercise of Pilates for eight weeks (three one-hour sessions per week). Desired variables of the subjects of both groups were evaluated 24 hours before the start of exercise and 24 hours after the last session. Data analysis was conducted using dependent and independent t-test by SPSS16 statistical software at the significant level of p≥0.05.
Results: The research results showed that the eight-week pilates exercise gave rise to reduction in blood pressure(p≤0.05) as well as resting heart rate (p≤0.05) and to increase in nitric oxide of elderly men with hypertension (p≤0.05).
Conclusion: The eight-week pilates exercise reduced blood pressure and resting heart rate and increased the production of nitric oxide in elderly men. So, it seems that the regular physical exercise can be effective as a preventive factor in the outbreak of cardiovascular diseases of the elderly men.
Eslam Zabihi, Seyed Eghbal Motavallibashi, Khayam Bamdad, Faegheh Pilevaribadi, Hamid Sheikhkanloui Milan,
Volume 20, Issue 3 (6-2017)
Abstract
Abstract
Background: The multiple sclerosis is a chronic disease of the central nervous system. Since the level of sex hormone and multiple sclerosis (MS) disease affects one another, the aim of this study was to evaluate the impact of the hydroalcoholic extract of truffle on the hormone levels of estrogen and progesterone administered in experimental model of MS-induced rats.
Materials and Methods: In this experimental study, 42 Wistar female rats, weighing 180±10 grams selected into 6 groups each consisting of 7 rats. Normal control didn’t receive any treatment and experimental group was given Cuprizone toxin (as a MS model inducer) for 40 days. The experimental groups (2, 3, 4 and 5) in addition to Cuprizone received the normal saline, 110, 220 and 330 mg/kg/0.2ml (i.p.) of Hydroalcoholic extract of truffle for 12 days too. Blood samples were taken at the end of the twelfth day from all groups involved and levels of sex hormones were measured.
Results: Cuprizone decreases estrogen, progesterone levels and also causes weight loss, while injection of hydroalcoholic extract of truffle increased serum levels of estrogen (in experimental group 4) and progesterone (in experimental group 4 & 5) compared to MS-induced group.
Conclusion: Results of the study revealed that the hydroalcoholic extract of truffle (at dosages of 220 and 330 mg/kg) could increase estrogen and progesterone levels in rats experienced experimental multiple sclerosis.
Aziz Eghbali, Hasan Taher Ahmadi, Shahla Zabihzadeh, Morteza Mousavi Hasanzadeh,
Volume 22, Issue 3 (8-2019)
Abstract
Background and Aim: Cancer is the second cause of death in children under fourteen years old. The aim of this study was to determine the epidemiology and predisposing factors of childhood cancers.
Materials and Methods: This observational-descriptive study was performed on 82 children in the oncology department of Amir-kabir Hospital in Arak who were referred between 2011 and 2016. Data on age, sex, type of malignancy and predisposing factors were carried out by person interviews or patient records and were registered in checklist and analyzed.
Ethical Considerations: This study with research ethics code IR.ARAKMU.REC.2.46.87 has been approved by research ethics committee at Arak University of Medical Sciences.
Findings: The results showed that 56.1 percentage of patients were aged 0-5 years, 74.1 percentage were urban, 90.2 percentage were alive, 99 percentage were singleton, 92.7 percentage full term, 46.3 percentage of them were the first children and 87.9% of them had birth weight over 2500 g. There was no significant relationship between the delivery method and delivery problems, the sex of the patients, the environmental factors (such as consuming canned food, sausages, insecticide use, drug use during pregnancy and the rate of infectious diseases), However, there was a direct relationship between the increased age of parents and the high socioeconomic level with the risk of cancer.
Conclusion: The risk of childhood cancers in Markazi province is more related to genetic factors and the environmental factors causing cancers in children are less involved in this study.
Masoomeh Sofian, Elahe Eghbal, Ehsanollah Ghaznavi-Rad, Amitis Ramezani, Pegah Mohaghegh,
Volume 22, Issue 4 (9-2019)
Abstract
Background and Aim Clostridium difficile is the main cause of Antibiotic-Associated Diarrhea (AAD) in the hospital setting. Today, the use of probiotics for the prevention and treatment of AAD and colitis is increasing. In this study, we investigated the effect of probiotic yogurt on the frequency of Clostridium difficile.
Methods and Materials In this randomized clinical trial study, 132 elderly patients admitted to the infectious ward of Vali-e-Asr Hospital in Arak, who were under antibiotic treatment, were randomly divided into two groups, case (yogurt probiotic, 200 mg/d for 8 days) and control group (common yogurt). All patients were trained about the signs of colitis. We evaluated the colitis signs and the presence of Clostridium difficile by Polymerase Chain Reaction (PCR) and compared them between the groups. The obtained data were analyzed with appropriate statistical tests in SPSS V. 16.
Ethical Considerations The Research Ethics Committee of Arak University of Medical Sciences approved this study (Code: 10-165-93). Also, it was registered at the Iranian Registry of Clinical Trials (Code: IRCT2016092229915N1).
Results Clostridium difficile was detected in 4 (6.1%) patients of the case, and 1 (1.5%) patient of the control group, at the beginning of the study. There was no significant difference between the frequency of Clostridium difficile and colitis syndrome between two groups at the end of the study (P>0.05).
Conclusion Probiotic yogurt has no significant effect in reducing the frequency of Clostridium difficile and colitis syndrome in our study.
