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Showing 11 results for Didgar

Farshideh Didgar,
Volume 2, Issue 7 (Summer 1999)
Abstract

In  this  report  we  present  a  care  of  cephalic  tetanus  in  a 57-year old  man  whose  onset  was  accompanied  by  right  facial  palsy  following  injuries  to  the  face. Three days  before  the  appearance  of  facial  palsy,  the  patient  have  had  a  wound  on  his  forhead  on  the  same side  and  seven  days  after  the  injury  the  parient  showed  trismus  lock  jow  dysonea  dysphagia  hoarsness  and  progressing  generalized  seizure  without  disturbance  of  consciousness  as  are  typical  in  tetanus. There  were  no  remarkable  finding  on  brain  CT  or  Laboratory  data. He  was  managed  as  a  case  of  tetanus  in  I.C.U. The  patient  was  completely  cured  and  he  discharged  on  the  35th  day  after  the  onset  of  right  facial  palsy.

Masoume Soufian, Farshideh Didgar,
Volume 2, Issue 8 (Autumn 1999)
Abstract

Cholera is potentially dangerous bacterial infection of the small intestine which may be serious enough to cause death, cholera epidemics cause economical and hygienic problems. In retrospective study, 54 cases were consider during 4 months admitted in Valie -asr hospital. Results were as follow:
There was no significant changes due to sex. Sixty percent of cases were above 50 years. 78% showed vomiting, 11% fever and bloody diarrhea which in half of above cases ameobic dyscentery was observed. In stool examination we observed 32% WBC, 14% RBC and 19% WBC along with RBC. Cell was not seen in 35% of the cases in 5.5% ameobic trophozoite observed. Hypokalemia were observed in 80% acidosis 21% and ATN in 50% which 82% of that resolved after treatment. In all cases with leukocytosis above 20000, ATN  have been observed. Rate of ATN and mortality in patients above 50 years significantly increased (4.9) and mortality and time of admission and observing initial symptoms. Due to above results may suggested that, leukolytosis above 20000 may be consider as a prognostic factor in incidence of ATN in above cases, also existence of WBC or RBC in stool smear can not denial eltor.

Mohammad Hassan Davami, Davood Hekmatpou, Farshideh Didgar, Mohammad Rafii, Mohammad Reza Khazai,
Volume 5, Issue 1 (Spring 2002)
Abstract

Introduction: One  of  the  most  important  health  problems  of  the  country  is  parasitic  infections, specially  intestinal  parasites  which  have  relatively  high  prevalence  rate  through  out  the  world. Theses  infections  can  cause  iron  deficiency  anemia, physical  and  mental  retardation  among  children  and  family  members.  Since  mothers  come  to  account  as  the  base  of  the  family  and  each  their  deviation  of  health  can  consider  as  a  risk  factor  for  them  and  the  other  family  members, this  study  was  conducted  to  determining  prevalence  rate  of  intestinal  parasitic  infections  among  mothers  and  associated  demographic  factors.
Materials  and  Methods:  This  survey  is  a  descriptive  analytical  study  which  cross-sectionaly  was  done  based  on  systematic  randomized  sampling  method  on  1650.  Mothers  in  three  regions  of  the  town.  Their  feces  were  examined  three  times  by  formalin  ether  concentration  technique.  Of course  for  gathering  data  about  demographic  factors, questionires  were  filled  all  infected  mothers.
Results: of  1650  case, 801  mothers (48.5%)  were  infected  by  intestinal  infections:110  mothers  (13.73%) m were  infected  by  pathogenic  intestinal  infection, Giardia  lambia 89 case (5.39%)  was  the  commonest  infection, entamoeba  histolytica  12  cases  (72%), hymenolepsis  nana  5  cases (3%), ascaris  3  case (1.18%)  and  tenia  saginata  1 cases  (0.6%)  respectively. 691  mothers  (869.2%)  were  infected  by  nonpathologenic  intestinal  infection.  E.coli  313  case(19%), blastocystic  hominis  267  cases  (16.18%), endolimax  nana 67  cases (4%), lodamoeba  buetschlii 34  cases, (25%)  and  chilomastix  mesnili  10  cases  (0/6%)  respectively.
Conclusion:  In this  survey, there  was  no  significant  relationship  between  infection  rate  and  demographic  factors  like  age, job, level  of  literary  and  residence  region. However  the  findings  showed  that  the  highest  rate  of  pathogenic  intestinal  parasitic  infections  were  7.8%  (43 cases) in  down  town, 6.72%  (37  cases)  in  town  center  and  5.45%  (30  cases)  in  uptown.
Hosein Sarmadian, Farshideh Didgar, Hamid Abtahi,
Volume 11, Issue 1 (3-2008)
Abstract

Introduction: Staphylococcus Aureus is one of the most important pathogenes in human. Regarding the ability of this bacterium in nasal colonization, carriers can increase the incidence of many nosocomial infections. This study was designed to compare the efficacy of two antimicrobial regimens (topical nasal Mupirocin and oral Ciprofloxacin) in treatment of Staphylococcus Aureus carriers and its recurrence. Materials and Methods: This study is a triple blind clinical trial that was performed on 366 cases of Vali-e-asr hospital personnel. Nasal cultures were prepared from all these cases. Among them, 45 cases were carriers which were divided in two groups (A and B). Group A were treated by single dose of oral Ciprofloxacin (1500 mg) and Vit A+D ointment as placebo for 5 days (twice a day) and group B were treated by single dose of oral placebo and nasal Mupirocin ointmdent for 5 days (twice a day). After this period, nasal cultures were repeated in the two groups to evaluate the efficacy of treatment. Also after 5 weeks the last cultures were performed in order to determine the prevalence of reinfection. Results were analyzed using Chi-square test. Results: Results showed that, 12.9% of Vali-e-asr hospital personnels were nasal carriers of Staphylococcus Aureus. Also the efficacy of topical nasal Mupirocin regimen (89.5%) was significantly higher than single dose of oral Ciprofloxacin regimen (55%) (p=0.019). But there was no significant difference between prevalence of reinfection in topical (13.3%) and oral regiment (20%). Conclusion: According to the present data, it seems that topical Mupirocin therapy is more effective than single dose of oral Ciprofloxacin in treating Staphylococcus Aureus carriers. However there is no significant difference in the prevalence of reinfection between the two methods.
Hossein Sarmadian, Nader Zarinfar, Ali Fani, Fateme Marjan Mousavi, Farshideh Didgar, Mohsen Khaki, Azadeh Mohammad Bagheri, Maryam Karimi,
Volume 11, Issue 3 (9-2008)
Abstract

Background: Metronidazole has antibacterial and antiparasitic action. Therefore it can use for treatment inflammatory diseases as Crohn. The effect of metronidazole on human’s blood lipids to reducing levels of LDL and VLDL and increasing level of HDL is under investigation. Target of this research is consideration effect of metronidazole on hyperlipidemia case of death such as coronary artry disrase. Methods and Materials: This study is a triple blind clinical trial was done on 100 voluntaries between 25-65 years old. with hyperlipidemia. Samples divided in two equal groups. The first group received metronidazol, 500mg, BID, for 10 days, and control group received placebo with the same dose. Lipids of serum were measured before and after using drugs, then data analyzed by SPSS software. Results: In metronidazol group amount of total cholesterol, LDL and Triglyceride were significantly less than placebo group. HDL’s amount in metronidazole group was significantly more than placebo group. Conclusion: Significant effect of metronidazole on reducing harmful blood lipids and increasing useful blood lipids. It can be suggested a probable candidate in treatment of hyperlipidemia. Maybe it can use with this application. Although it needs to more study by meta analysis to validate this effect.
Mina Mirnezami, Farshideh Didgar, Akbar Hasanpoor, Hosein Sarmadian,
Volume 13, Issue 1 (4-2010)
Abstract

Background: Herpes simplex clinical manifestations are in the form of vesicular eruptions on erythemateus base. The virus can remain latent within sensory nerve ganglions following the initial infection and be reactivated in some cases such as intracranial surgery, dental surgery, stress and excitements. Systemic or disseminated infection occurs in immune-deficient patients and sometimes in healthy individuals. In Previous studies, in most of the disseminated infection cases, visceral organs involvement has been mostly observed while skin involvement has been reported just in one case. Thus, our patient was the second case with herpes simplex disseminated skin infection. Case: The patient was a 38 year-old man who underwent craniotomy surgery due to epidural hematoma following car accident and head trauma. Almost 10 days after the surgery, the patient developed disseminated vesicular eruptions in erythemathous base which initially appeared in the face, head, and then in body and extremities. Fever was detected 5 days before the development of eruptions. Other than anemia and leucocytosis, there were no other notable points in the systemic examination and lab tests. For patient skin biopsy was taken with an impression of herpes simplex, mulocum contagiosum and a lower probability for bullouse diseases. In the skin biopsy, intra-epidermal vesicles and extensive epidermal necrosis with multinucleated giant cells and intra-nuclear objects were observed. A plethora of neutrophilic cells inside the vesicles and inflammatory cell infiltration in the underlying debris were seen. Based on the pathology report, infection with herpes simplex hominis was confirmed. Conclusion: Disseminated skin infection with herpes simplex can be observed even in healthy people with no background.
Farshideh Didgar, Majid Akbari, Hossein Sarmadian, Masoomeh Soufian,
Volume 13, Issue 3 (9-2010)
Abstract

Background: Brucellosis, a zoonotic disease with worldwide spread, is a common disease in Iran and is endemic in Markazi Province. Brucella osteomyelitis, on the other hand, is a rare disease. Here we reported a case of brucella osteomyelitis of the tibia following trauma. Case: The patient was a 22 year old man referring with chronic draining tibia ulcer. He had a history of trauma of the tibia, dating back to 3 years ago, for which local prosthesis had been prescribed. Later on, the prosthesis had been removed due to infection. Staining of the tissue samples indicated the presence of gram-negative coccobacill and brucella growth in the culture of excretions. Conclusion: This case was reported because of rare presentation of brucella and the educational implications of the patient with respect to the possibility of brucella development in chronic ulcers or prosthesis. Although uncommon, brucellosis should be regarded as a potential cause of osteomyelitis in patients with a record of physical contact with animals.
Fardin Faraji, Farshide Didgar, Afsun Talaiee,
Volume 15, Issue 7 (December 2012)
Abstract

Background: Cerebral venous sinus thrombosis is a rare form of brain stroke caused by thrombosis in venous sinuses of Dura. This study reports on a patient with venous sinus thrombosis and brucellosis who presented with uncontrolled seizure. Case: A 33-year-old woman with past history of controlled complex partial seizure who presented with headache, asthenia, and uncontrolled seizure for one month is described in this study. She was febrile and in brain CT scan hemorrhagic focus in left posterioparietal and temporal lobe was reported. MRI and MRV proved venous sinus thrombosis in left transverse sinus. In laboratory assessment, brucellosis was confirmed as well. The patient treated with anticoagulant, anti-brucellosis, and antiepileptic agents and discharged in good condition with medication orders. Conclusion: Clinical suspicion and accurate evaluation is the most important clue in the diagnosis and treatment of brucellosis and venous sinus thrombosis, especially in uncontrolled seizure in patients who had previously been under control.
Hossein Sarmadian, Farshideh Didgar, Massoumeh Kalantari, Nader Zarinfar, Mojtaba Ahmadlou,
Volume 16, Issue 12 (3-2014)
Abstract

Background: Motivation is one of the most important tools to push faculty members to perform effectively and efficiently in the workplace is. This study is based on Herzberg's theory of motivating factors to consider requiring faculty at the University of Medical Sciences deals.

Materials and Methods: In this cross-sectional study, a total of 168 faculty members of Tehran University of Medical Sciences, 102 persons conducting a completely free and informed, a 40-question questionnaire based on Herzberg's two-factor theory, design, a questionnaire. Data using t-test and Mann-Whitney U and indicators of central tendency and dispersion were analyzed by SPSS 16 software.

Results: Response rate to the questionnaires, 7.60, respectively. 5.24% of the faculty in the basic sciences and 5.74% at the clinical level of activity. Of "communication" and "progress and development", the motivation faculty have the greatest impact. Factors "physical condition" and "salary" have been less effective. Between the ages of faculty motivating factors, "nature", "responsibility and career" and "supervision and monitoring", there was a significant correlation. The relationship between work experience and of "salary" and "job security" was also significant.

Conclusion: Communication is one of the most important factors in increasing the motivation of faculty members in the physical conditions of work and wages are minimal impact in this area. With an aging faculty, salary, supervision and monitoring, and job security are more important motivation. In other words, with increasing age and work experience, academic expectations of the management of change and the proper evaluation of the activities of the officials do not have the decision-making, and because the quality of activities, good participate Ndah encouraged do not motivate members to create good will.


Aliasghar Farazi, Nader Zarrinfar, Farshideh Didgar, Mansoureh Jabbariasl, Parisa Mirzajani,
Volume 17, Issue 4 (7-2014)
Abstract

Background: Treatment failure and relapse is a major problem in the treatment and control of brucellosis. The present study directed to determine risk factors for failure of treatment and relapse in patients treated for brucellosis.

Materials and Methods: This study was a descriptive - analytic and prospective study and were conducted in 72 patients with acute brucellosis.Patients were followed up during treatment and for six months after completion of therapy, and patients with treatment failure or relapse were analyzed. All data analyzed using SPSS software and P-value of less than 0.05 was considered significant.

Results: The mean value of age in patients was 40.2 ± 16.5 years. Treatment failures was 6.9% and the relapse at the end of the ninth month was 12.5% that recurrence of symptoms were associated with increased titers of serological tests and 80.6 percent had successful treatment. In this study gender of male (P = 0.026), occupational exposure (P = 0.005), delayed treatment in less than two weeks (P = 0.016), hepatosplenomegaly (P = 0.003), thrombocytopenia (P = 0.023), CRP &ge +2 (P = 0.017) and Wright &ge 1/320 and 2-ME &ge 1.160 at the end of the sixth week of treatment (P = 0.004 and P = 0.010) were risk factors of treatment failure and relapse in brucellosis.

Conclusion: The diagnosis and treatment of relapse and treatment failure in acute brucellosis is not clear, therefore, the prediction of relapse may be useful in preventing recurrence and treatment of patients.


Farshideh Didgar, Gholamreza Noori Broujerdi, Nasrinsadat Mirtalaee,
Volume 18, Issue 5 (8-2015)
Abstract

Background: Hydatid disease is a zoonotic infestation by a tapeworm of the genus of Echinococcus that characterized by cystic lesions in the liver and lungs but rarely in other parts of the body.

Case: Known case of chronic Lymphocytic leukemia was a 56-years old man with several hydatid cysts of liver and lungs that was hospitalized because of ascites and abdominal pain. The patient received albendazol and surgical operation with diagnosis of peritonitis and complicated hydatid cyst in lungs and liver and Peritoneum. Patient expired with DIC and sepsis.

Conclusion: This case report provides evidence that complicated hydatid cysts in immunocopromised patients have a bad prognosis and can not be safely treated by medication and surgery.



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