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Introduction: Nearly, 6% of recently diagnosed cancer in the United States was upon to lymphoproliferate and leukemia and 9% of fatality in cancerous people was upon to these two illnesses. Using some simple, cheap and in-hand tests and special consideration to clinical inspections in suspected subjects provide a faster diagnostic and suitable treatment. It may ultimately promote the quality of life and decline the fatality among patients.
Materials and methods: This was a cross-sectional investigation which carried out during a 1.5 years in the form of forward direction. Forty-two lymphoproliferate (28 lymphoblast and 14 Hotchkin) and 21 acute lymphoblastic leukemia (10 acute lymphoblast leukemia and 11 miloid acute leukemia) subjects were evaluated. ESR, LDH and ALP levels were measured in all patients. In clinical examinations, oversizing of lymph nodes, spleen and liver were exactly considered.
Results: According to our results the best tests to rule in and rule out acute leukemia from lymphoprolifeatives were ESR and LDH, respectively. Additionally, The most sensitive and specific evaluations to rule out these two diseases were LDH and oversizing of liver inspection. It was also determined that LDH is the best screening test to rule out leukemia from lymphoproliferate.
Conclusion: Using of simple examinations such as ALP, LDH, ESR and more consideration to oversized spleen, liver and lymph nodes in each suspected patients, we could easily differentiate lymphoproliferate and acute leukemia from each other.

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Background: Essential hypertension which affects 1 billion people worldwide is a multifactorial disorder and influenced by genetic and environmental factors. In human at about 14th week of pregnancy, sweat gland anlagen appear at uniform intervals along the apices of the epidermal ridges. Once the pores of sweat gland form on the ridge, they are fixed at that location. Considerable amount of researches have shown that pores do not disappear, move or spontaneously generate over time. The goal of the present study was to examine whether there is a relationship between the number of palmar sweat gland pores and hypertension condition. Methods: By applying a digital microscope, the number of palamr sweat gland pores were counted in a circle area (12.5 –16.8 mm2) of certain anatomical regions (a, b, c triradials and fingers) in 75 hypertensive and 55 normotensive females. The average age of all patients was 60 years and the average age of all controls was 49 years and all patients had a familial background of hypertension. Results: Statistical analysis of the data showed that the mean count of sweat gland's pores on fingers and b triradial in hypertensive group was significantly lower than normotensive subjects. Conclusion: In conclusion, the results obtained from the present study indicate that there is a meaningful relation between the numbers of fingertip sweat glands pores and hypertension. This finding can be used for the prognosis and early detection of hypertension in susceptible persons, particularly among those with a familial background.

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Background: Endothelial cells are very sensitive to mechanical force including microgravity and the morphological and functional changes in them are believed to be at the basis of weightlessness-induced cardiovascular deconditioning. It has been shown that the proliferation, migration, and morphological differentiation of endothelial cells play critical roles in angiogenesis. So far, the influence of microgravity on the ability of endothelial cells to foster angiogenesis remains to be explored in detail. The aim of this study was to investigate the effect of microgravity condition on VEGFR-2 and CD34 genes expression in human umbilical vein endothelial cells (HUVEC) in angiogenesis.

Materials and Methods: In this study, HUVEC cells were purchased from Pastor Institute. We used a clinostat to simulate microgravity condition for 2, 24 and 72 hours. Real time PCR technique was used for gene expression analysis after extraction of RNA from cells.

Results:  Our results showed that microgravity for 72h leads to a significant increase (6 times compared with control group, p<0.001) in the VEGFR-2 gene expression. However, expression of CD34 did not change (p>0.05) with microgravity.

Conclusion: Based on the results, microgravity has positive effect on angiogenesis and can be used to generate vascules for cell therapy of ischemic diseases and atherosclerosis.