Journal of Arak University of Medical Sciences

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Showing 2 results for Changizi-Ashtiyani

The Effect of Increasing Resistance Training on Testicular Oxidative Stress and Quality of Spermatogenesis in Male Rats

Amin Mombeyni, Mehdi Bahmanzade, Abbas Sarami, Saeed Changizi-Ashtiyani, Mohammad Parastesh,
Volume 21, Issue 4 (8-2018)

Abstract

Background and Aim: Following physical activity in various tissues of the body, oxidative stress occurs and affects the antioxidant capacity and consequently the fertility of men negatively. The aim of this study was to investigate the effects of resistance training on oxidative stress and spermatogenesis quality.
Materials and Methods: 20 male rats of Sprague Dawley (weight 200-250, 4 months old) were randomly divided into two groups of resistance training and control group (n = 10). The exercise program included climbing a ladder by hanging the load to the tail for 8 weeks (5 days a week, 3 times 4 repetitions). During the program, the load gradually was increased, and in the last week, it reached to 200% of the animal body weight. After intervention, the mice were anesthetized in separate groups and testicular tissue was isolated to evaluate Malondialdehyde index as an oxidative stress marker and to determine antioxidant capacity by Frap method. Fixation, processing, cutting of testicular tissue and eventually coloring steps were examined by Hematoxylin and Eosin (H & E). The spermatogenesisqualitywas calculated based on Johnson method. The data were analyzed by independent t-test was used and significance level was considered p <0.05.
Findings: Increased Malondialdehyde levels were observed in the treatment group compared to control group (p =0.01). In the training group, the spermatogenesis quality was lower (p =0.013), the antioxidant capacity in the training group was significantly higher than the control group (p‏=0.83) and there isn’t any significant difference.
Conclusion: The findings indicate thatdue to increased oxidative stress, increasing resistance training may have negative effects on the quality of spermatogenesis and men's fertility.

The Effectiveness of Rosa Canina Plant in Treatment of Some Diseases: A Brief Review

Saeed Changizi-Ashtiyani, Majid Ramezani, Hossein Poorcheraghi, Seyed Mohammad Afzali, Parand Pirouzi, Sina Atashi, Ali Zarei,
Volume 22, Issue 5 (11-2019)

Abstract

Background and Aim Among the plants with multiple healing properties and a long and common history of use in Iranian traditional medicine, is dog-rose plant with the scientific name of “Rosa canina” that belongs to the Rosaceae family. This study aimed to review the effectiveness of Rosa canina in treatment of different body organs and tissues and emphasizes its therapeutic mechanism.
Methods & Materials This is a review study. About 176 papers published from 2010 to 2018 were extracted from PubMed, Science Direct, Scopus, Google Scholar, Ovid, MagIran, and SID databases using related keywords and entered into study.
Ethical Considerations Ethical issues (including plagiarism, misconduct, data fabrication, falsification, double publication or submission, redundancy) have been completely observed by the authors.
Results Different studies had indicated the importance of Rosa canina as a medicinal plant protecting liver, lowering glucose and lipid levels, and having antioxidant and anti-inflammatory properties. The highest flavonoid activity in the Rosaceae family is related to Rosa canina. The use of herbal extracts in the treatment of common diseases, such as diabetes, fatty liver, urinary tract and Alzheimer's, has been recommended.
Conclusion High qualitative and quantitative diversity of effective ingredients, ease of access, absence of adverse effects of consumption and endemic nature of Rosa canina plant make it necessary to use it for the control and treatment of common human diseases.

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