Showing 25 results for Ashraf
Dr Tahereh Ashraf Ganjoei, Dr Tayebeh Naderi, Dr Babak Eshrati, Dr Nushin Babapoor,
Volume 9, Issue 1 (3-2006)
Abstract
Introduction: Estimation of fetal weight is very important in preventing delivery complications and also in selecting delivery method. This is specially important in potential macrosomia, IUGR and also preterm labor. The objective of this study is to compare the accuracy of ultrasonic, clinical and mother, fetal weight estimation in pregnant women in Kerman. Materials and Methods: In this cross sectional study 246 women with singleton, term pregnancies admitted for cesarean section within the following week, were studied. Estimation of fetal weight (EFW) was done using sonography and then by two obstetricians and one senior resident who were unaware of the other clinical and ultrasonic results. Mothers' estimation of their baby weight was also asked. Statistical analysis was done by paired T and Chi square tests. We also used ROC (Radar Operating Characteristics) curve to compare the accuracy of different tests. Results: Fetal birth weight was 3339±443 gr. In the 2500-4000 gr birth weight the sensitivity of predicting clinical birth weight was 11.8% with 99.6% specificity and for sonographic EFW was 12.6% with 92.1% specificity. Conclusion: Clinical estimation of birth weight in term pregnancies is as accurate as routine ultrasonic estimation obtained in the preceding week of delivery.
Dr Javad Baharara, Dr Kazem Parivar, Dr Shahrbanou Oryan, Dr Alireza Ashraf,
Volume 9, Issue 2 (6-2006)
Abstract
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Introduction: The increasing use of EMF (electromagnetic field) generating apparatus (refrigerators, computers, TV, etc) caused an increasing interest in investigations of its adverse effects on human health. This study is done to investigate the effects of EFM on Balb/c mice.
Materials and Methods: This is an experimental study in which at first a circuit generating low frequency electromagnetic field (50 Hz, 15G) was designed. Then adult virgin female mice were placed in coil and exposed to 15 gauss electromagnetic field for 4 day and 6 hour per day. Then their blood was examined to assay the level of hormones (FSH, LH, estradiol, progesterone). Also ovary and uterus sections were studied with light & electronic microscope.
Results : Results showed that the weight and size of ovary was not significantly affected in females exposed to the low frequency electromagnetic field and their offspring. Our results also showed that the number of ovary follicles were significantly affected in exposed females (p<0.05). Also the study of micrographs showed hetrochromatinated oocytes and follicular cells and increasing polysomes, accumulation of mitochondria and cleft nucleus. Decreasing amount of FSH, LH and 50% decrease in couplation rate was also seen as compared with the control group.
Conclusion: Results of this study is indicator of EFM effects on gonads, structure and endocrine system and decreases fertility.
Dr Ali Chehrei, Dr Manijeh Kahbazi, Dr Bahman Salehi, Dr Afsaneh Zarganj-Fard, Dr Fatemeh Darreh, Dr Parvin Soltani, Dr Ashraf Zamani, Dr Mohammad Khalili, Dr Afsaneh Noroozi,
Volume 9, Issue 2 (6-2006)
Abstract
Introduction: Performing correct research in different aspects of community as well as medical sciences can be a way to resolve many problems. In order to create a systematic knowledge of research method in academic members of Arak University of medical sciences and enabling them in providing proposals and performing researches, a clinical research center was developed. This study is done to investigate the effect of this center on improving clinical researches in the University. Materials and methods: This is a HSR, before and after, interventional study in which, clinical academic members of Arak University of medical science were evaluated. First the information of the pre intervention period was gathered (jan2002-jan2004). Then the intervention was done in the form of developing a research center in Vali-Asr hospital, performing serial research workshops, research conferences, research consultations and planning data bases during a 2 years period. Again data was gathered and then compared to those of pre intervention period. Results: The comparison of pre and post intervention periods showed that in pre intervention period from 38 proposals 30 and in post intervention period from 89 proposals 76 were approved by research committee of the University. In the two pre and post intervention periods 14(46.6%) and 50(65.8%) of accepted proposals were clinical respectively. Also from the view point of quality, 11 and 15 proposals were HSR, 2 and 22 clinical trials and 8 and 8 descriptive, respectively. The number of published articles in first period was 45 and in second 84. Presented articles in internal and external congresses were 33 and 59 in the two periods overally, which 25 and 51 articles were presented in the country and 8 and 8 in abroad congresses, respectively. Conclusion: Regarding the results it seems developing research center in this University and other similar Universities can have a significant effect on the process of clinical researches.
Hamidreza Jamilian, Esmat Mashadi, Ali Ghazavi, Mehri Jamilan, Maryam Eftekhari, Ashraf Moradi,
Volume 9, Issue 3 (9-2006)
Abstract
Introduction: An association between depression and altered immunity has been suggested by a number of studies but has not been consistently demonstrated .The effect of maternal depression response on fetal immune system have not been investigated. Thus in this study we evaluated the effects of depression on some parameters of innate and humoral immune system of pregnant women and their infants. Materials and Methods: 62 pregnant women (including 32 depressed and 30 healthy) and their infants in Taleghani hospital of Arak in 2004 were included in this study. All depressed mothers had a diagnosis of depression by Beck Depression Inventory (BDI) and clinical interview based on DSM-IV system. The level of immunoglobulins and components were evaluated by single radial immunosdiffusion (SRID) method of Mancini. Leukocyte and lymphocyte counts were determined by Hycel (an automated cell counter) and for more accurancy were also evaluated by manual method. Statistical analysis was performed using K-S, Mann-Withney, One way ANOVA, Kruskal-Wallis and Pearson tests. P<0/05 was considered significant. Results: Serum IgM level and serum C4 level of infants of mothers with depression were significantly lower than infants of healthy mothers. Lymphocyte number and percentage in infants of depressed mothers was also significantly higher than infants of healthy mothers. The mean cord/maternal blood ratio of IgG in infants of depressed mothers was also significantly lower than infants of healthy mothers. Serum IgG level of depressed mother was significantly higher than other mothers. Conclusion: Fetal impact of stress and depression during pregnancy is just beginning to be understood and research in this area is developing. Our results indicated that maternal depression adversely affects the development and function of fetal immune system. These results are in agreement with the immunological findings of preterm and LBW infants.
Javad Baharara, Alireza Ashraf, Mahmoudreza Jafari, Hoda Halalat,
Volume 10, Issue 3 (6-2007)
Abstract
Introduction: The increasing users of microwave appliances such as cell phones caused an increasing interest on investigation of its adverse effects on human health and development of animals.This study is done to investigate the effects of simulating cell phone waves on gonads and sex cells of male Balb/C mouse. Materials and Methods: This is an experimental study in which with the use of generating apparatus of simulating cell phone waves, adult male mice were exposed to cell phone waves for 10 days (4 hours per day). Then structure and ultrastructure of testes and number of sex cells were examined by light and transmission electron microscope. Data was analyzed using t and Mann Whitney testes. Results: The results did not show any significant differences in the size and weight of testes in mice exposed to the simulating cell phone waves. Results also showed that the number of spermatogonia cells and primary spermatocytes and spermatids and sperms were significantly increased in exposed mice (p<0.05), but the number of sertoli cells were significantly decreased (p<0.05). The study of micrographs showed changes in ultrastructure of sexual cells, such as cleft and hetrochromatined nucleus and decrease of cell organelles and vacuolization of cytoplasm. Conclusion: Results indicate the effect of simulating cell phone waves on number and ultrastructure of sex cell in male Balb/C mouse.
Javad Baharara, Farhang Hadad, Alireza Ashraf, Elham Khanderoo,
Volume 11, Issue 2 (6-2008)
Abstract
Introduction: The increasing use of the electromagnetic field producer sets in daily living causes concerns about these waves on human health. The effects of extremely low frequency electromagnetic field (50 Hz) on induction of chromosomal damages on bone marrow erythrocytes of male Balb/C mouse has been investigated in this research. Materials and Methods: This is an experimental study in which the laboratory system of producing electromagnetic with low frequency (50 Hz) was used. Five week old male Balb/C mice were divided into three controls, sham-exposed and experimental groups. The experimental mice exposed were exposed to electromagnetic field (50 gauss) for 4 days (12 hours/day). After treatment, the chromosomal damages were assessed using micronucleus test in polychromatic erythrocytes and resultant quantity data were analyzed using t and Mann-Whitney test. Results: Results showed that frequency of micronucleated polychromatic erythrocytes of experimental group (14/35±1/589) was more than Sham-exposed (8/958±1/049) and control group (7/65±0/768) significantly (p<0/05). Conclusion: Extremely low frequency electromagnetic field (50 Hz) causes chromosomal damages induction in polychromatic erythrocytes of bone marrow male Balb/C mouse.
Mitra Hatefi, Sedigheh Mehrabian, Ashraf Sadat Nouhi, Robab Rafiee Tabatabaee,
Volume 11, Issue 2 (6-2008)
Abstract
Introduction: In this study, antimutagenesis effect of ethanolic extract of propolis by Ames test against two mutagenic substances named azide sodium and potassium permanganate in the presence and the absence of microsomal homogenate of mouse liver (S9) has been investigated. Materials and Methods: In this experimental study at first, different concentrations of ethanolic extract of propolis (0.1-5%) for determining minimum inhibitory concentration (MIC) against tester strains were used. Then by Ames test, antimutagenesis effect was assessed in nontoxic extent. In this test, various strains of Salmonella typhymurium (TA100 and TA97) that contained selective mutation in their operon histidine, were used. Mutant strains (His-) were grown on culture media containing minimum salt and glucose in the presence of mutagen substances above. So only those bacteria that were reversed by mutation (His+) could grow and form colonies on culture media. If antimutagen (EEP) and mutagen substances were gathered, reversed mutation would be reduced and the rate of mutation inhibition could be calculated by means of formula. The differences between the averages of revertants per plate of the sample in relation to the mutagens were analyzed using SPSS software and one-way ANOVA. Results: The resulted MIC values clearly showed that ethanolic extract of propolis at 5% concentration has antibacterial activity against Salmonella typhymurium, but in 0.1-4% concentrations, such effects were not seen. Findings also showed that propolis in such concentrations could neutralize mutagenic effects of those substances in a dose dependent manner. Conclusion: Finally we found that ethanolic extract of propolis that contains different kinds of major and important substances like flavonoids, has good antimutagenic effects and the best concentration for obtaining such effect is in 4% which also was confirmed with microsomal results. The mechanism of antibacterial effect of propolis is complex and it has no analogy to any classic antibiotics, but it should be emphasized that bacterial cell division is inhibited by propolis. Some researchers also argue that propolis could inhibit DNA-dependent RNA polymerase.
Soleyman Zand, Ashraf Zamani,
Volume 11, Issue 3 (9-2008)
Abstract
Background: Backache is a common problem in pregnancy period . Scientists believe that some simple exercise can help to prevent the occurrence of backache during their pregnancy period. Thus, this research carried out in order to investigate the effect of some simple exercises and correct daily activity in prevention of backache in pregnancy period. Methods and Materials: This is a clinical trial study that was carried out on 138 of pregnant women .The first group including 66 women which considered as control group and treatment group including 72 women. The research had four stages: 1) stage of taking history. 2) Arrange a teaching program. 3) stage of performance( In case group samples were done 60 minutes aerobic exercises for 3 days a week for the 30 weeks undersupervision a physiotherapist). 4) Assessment the results. Data were analyzed by SPSS for statistical analysis. Results: According to the result 18.2% of woman that were under treatment and 36.6% of control group, suffered from backache. Chi-square test showed significant differences between two groups. In addition Odd ratio of treatment population was 2(CI%95 = 4/04-1/91 & p<0/05). Conclusion: The result showed simple exercises during pregnancy period can not eliminate backache, but it can decrease delay backach.
Hamid Momeni, Ashraf Salehi, Abolfazl Seraji,
Volume 12, Issue 4 (2-2010)
Abstract
Background: Job burnout is a common consequence of job stress among nurses which has negative impacts on the quality patient care and physical and mental health status of nurses and it imposes some expenses on health care system. This research aiming at comparing burnout level among the nurses in Markazi province can offer some solutions for reducing burnout and improving self-esteem in nurses. Materials and Methods: In this descriptive cross-sectional survey, via stratified random sampling, 66 nurses working in the clinical sections of governmental hospitals in Arak, Khomein and Saveh and 33 nursing instructors and nursing faculty members of Arak University of Medical Sciences who had their BSc or MSc in nursing were selected. Maslach Burnout Inventory was then administered to the participants. Results: Mean of Job burnout (40.84%) in this research was higher than that of other similar studies. Mean of emotional exhaustion scores, depersonalization and personal accomplishment were 28.38, 9.41 and 29.31, respectively. The difference between occupational burnout in nurses working in the clinical sections and those in the educational departments were significant in the domain of depersonalization. But in other domains, no statistically significant differences were seen between the two groups. Conclusion: Job burnout among educational and clinical nurses is generally high in Markazi province. This can be decreased through such special ways as increasing job stability and freedom of action, clarification of individual responsibility regarding personal performance and dividing tasks among the members for lowering workload.
Javad Baharara, Kazem Parivar, Alireza Ashraf, Roya Rostami,
Volume 12, Issue 4 (2-2010)
Abstract
Background: Noticing the daily advancement of the role of electromagnetic field generators in human life, examination of the biologic impacts of these waves has come to be extensively appreciated by researchers. During pregnancy, vitamin A is extremely essential for the development of fetus and its lack, insufficiency or excess can result in embryonic malformations. This study investigated the synergetic effects of vitamin A and extremely low frequency electromagnetic fields on the development of embryo skin in Balb/C mice. Materials and Methods: This study was experimental in nature. Eighteen pregnant mice were divided into control, sham-exposed and experimental groups. The mice in the experimental group were given an intra-peritoneal injection of 15000 IU/kg vitamin A on the 10.5th day of gestation and were, then, exposed to a 50Hz electromagnetic field 4 hours a day from 10 through 12th day of gestation. The animals were dissected and investigated morphologically and histologically on 17.5th day of gestation. Results: The results showed an increase in the mean weight of fetuses in the experimental group in comparison to the sham- exposed group (p<0.05). Also, Crown-Rump of fetuses in the experimental group increased in comparison to those in the sham- exposed group (p<0.001). Epidermis thickness increased significantly in experimental group in comparison to sham- exposed (p<0.05), while the average number of basal, spinous cells and hair follicles decreased significantly in the experimental group compared to the sham- exposed (p<0.001). Conclusion: The findings indicate that vitamin A usage and synergetic exposure to low frequency electromagnetic fields (50Hz) profoundly affect the development and growth of skin epidermis in the fetus of Balb/C mouse.
Omid Teimornejad, Ashraf Mohebi, Reza Hosseini,
Volume 13, Issue 2 (6-2010)
Abstract
Background Vancomycin resistant enterococcus (VRE) is the third major cause of nosocomial infections in hospitals after staphylococcus and E. coli. The aim of this study was to evaluate resistance pattern of VRE to the antibiotics recommended by CLSI. Materials and Methods: In this clinical trial, 833 enterococci, obtained from urine, wound, blood, and stool, were selectively collected from hospitals in Tehran. After verification of the VRE isolates through the use of 30µg vancomycin disc and agar dilution, VREs were isolated, and their inhibiting concentrations were determined. The sensitivity of these enterococci to antibiotics was assessed at CLSI’s M100 standard. Results: Of the 833 isolated enterococci, 4% had a high level of resistance to vancomycin, and 38.5% had a low level of resistance to vancomycin. Of the VREs, 8.5%, 85%, 50%, 42%, 94%, 30%, 70%, 24%, 6%, and 97% were resistant to vancomycin, ampicilin, erythromycin, tetracycline, rifampin, chloramphenicol, gentamicin, synercid, linozolid and penicillin, respectively. All these VRE isolates were sensitive to nitrofurantoin. Conclusion: In this study, all VRE isolates were sensitive to nitroforantoin, and this antibiotic, as a drug of choice for urinary tract infections, can also be recommended in the treatment of resistant enterococci.
Abolfazl Seragi, Hamid Momeni, Ashraf Salehi,
Volume 13, Issue 3 (9-2010)
Abstract
Background: One way of quitting addiction is forming narcotics anonymous (NA) groups. Noticing the high rate of reappearance of drug usage in these groups, the researchers decided to obtain a proper method of increasing the duration of abandonment period through the analysis of different factors affecting the reappearance of addiction. Materials and Methods: In a cross-sectional analytical study, all NA members (350 men) in Khomein were evaluated through questionnaire and referral interview. Data related to factors affecting quitting addiction, development of addiction, and reappearance of addiction were analyzed. Results: The most important causes of addiction were enjoyment and curiosity (75.1%), whereas the most important factors in abandonment were weariness and pressure from family (45.4%). Also, 48.9% of individuals had previously relapsed into using narcotic substances. The most important factors in reappearance of addiction in NA groups were unemployment and change in income (12.6%). A significant relationship was found between level of education and place of living and addiction to narcotics (p=0.000), whereas there were no significant relationships between the type of narcotic substance and quitting addiction or the mean age of individuals and trying or not trying to quit. Conclusion: Noticing the high rate of reappearance of narcotics usage in NA groups, it seems that current programs for prevention of addiction have not been successful in this regard. However, based on the findings of this study, it is suggested that provision of employment opportunities after quitting addiction can, to some extent, prevent the reappearance of addiction in NA groups.
Amin Talebi Bezmin Abadi, Ashraf Mohabati Mobarez, Tarang Taghvaei,
Volume 13, Issue 3 (9-2010)
Abstract
Background: Helicobacter pylori iceA gene has been reported to be a genetic marker for the development of peptic ulcer in western populations. The aim of this study was to investigate the prevalence of iceA genotypes and their relationship with peptic ulcer in Iran. Materials and Methods: This observational study was carried out on 75 patients. Biopsy specimens were evaluated for the presence of Helicobacter pylori through rapid urease test. GlmM gene and iceA1 and iceA2 genotypes allelic verification and variation culture were determined via PCR. Results: In this study, iceA1 and iceA2 alleles were identified in peptic ulcer disease (PUD) patients. IceA1 genotype (64%) was more prevalent than iceA2 (21.3%). IceA1 strains were more observable in patients with PUD. No significant relationships were seen between iceA genotypes and the clinical outcomes following infection (p= 0.71). Conclusion: This study revealed a significant two-tailed correlation between iceA genotypes and PUD occurrence. The results indicate that iceA1 gene can be used as a reliable marker in predicting the clinical outcomes of Helicobacter pylori infection. Therefore, further in-vitro and in-vivo investigations are needed for reaching general consensus in this regard.
Mohammad Shayestehpour, Mohammad Kazem Shahkarami, Abbas Shafyi, Mohammad Taqavian, Razieh Kamali Jamil, Fatemeh Esna-Ashari, Ashraf Mohammadi, Reza Shahbazi,
Volume 15, Issue 4 (September 2012)
Abstract
Background: Noticing the sensitivity of measles virus to temperature and light, maintaining its stability is highly important in live vaccines. The aim of the study is to evaluate the stability of measles vaccine produced by AIK-C strain. Materials and Methods: In this experimental study, three lyophilized vaccine vials were incubated at 37˚C for one week and their stability was evaluated via accelerated test. In addition, reconstituted vaccines were incubated at 4˚C, 25˚C, and 37˚C for 0, 4, 8, 12, 16 hours after reconstitution and their remaining infectious virus titer was measured using CCID50 method. Half-life of the reconstituted measles vaccine was evaluated according to linear regression analysis. Results: When the reconstituted vaccine was incubated at 4˚C, 25˚C, and 37˚C, the titer loss per hour was equal to 0.05, 0.1 and 0.2 Log10 CCID50, respectively. Also, the half-life of this vaccine at these temperatures was 5.31, 2.26, and 1.36 hours, respectively. Conclusion: The loss of potency for measles vaccine produced by AIK-C strain is 0.33 Log after storage at 37°C for one week, while the reported amounts for commercial vaccines such as Mevilin-L, Attenuvax, Edmonston-Zagreb, and Rimevax are 0.7, 0.7, 1 and 0.78, respectively. Lyophilized and reconstituted vaccine containing AIK-C strain is more stable in comparison with Edmonston B, Schwartz, Biken-CAM, and Leningrad strains. The stability of the reconstituted AIK-C strain vaccine is similar to Moraten strain at 37˚C.
Zatollah Asemi, Ashraf Khorrami, Mohsen Taghizadeh, Zahra Abedini, Ali Akbar Rashidi,
Volume 15, Issue 6 (November 2012)
Abstract
Background: Protein-energy malnutrition is regarded as one of the public health problems in developing countries as a result of poor feeding due to poverty. This study was conducted to compare protein quality of two samples of commercial weaning food, Cerelac (based on dry milk, wheat and banana containing probiotic Bifidobactriumlactis) and Ghoncheh (based on dry milk, wheat, and honey), in rats. Materials and Methods: This experimental study was conducted on 64 male rats aged 23 days in 8 groups under 8 diets, including 2 test diets (Cerelaccontaining probiotic Bifidobactriumlactis and Ghoncheh), 1 standard diet (casein), 1 basal diet (protein free) for true protein digestibility and apparent digestibility study, 2 test diets, 1 standard diet, and 1 basal diet for net protein ratio, protein efficiency ratio, and food efficiency ratio study. Results: The contents of true protein digestibility for casein, Cerelac, and Ghoncheh were 93.77, 84.23 and 89.82, respectively and the results were significant in all of the groups (p<0.001). The content of net protein ratio for casein, Cerelac, and Ghoncheh was 4.38, 4.1 and 3.17, respectively and the results were significantin all of the groups (p=0.009). The contents of protein efficiency ratio for casein, Cerelac, and Ghoncheh were 3.05, 2.59, and 2.01, respectively and the results were significant in all of the groups (p<0.001). Conclusion: The findings of this study indicated that the protein value of Cerelaccontaining Bifidobactriumlactis was higher than Ghoncheh.
Navid Mazruei Arani, Homa Baghaei, Ashraf Khorrami Rad, Zatollah Asemi, Sabiheosadat Alizadeh, Ahmad Esmaeilzadeh,
Volume 16, Issue 6 (9-2013)
Abstract
Background: Increased insulin resistance, inflammatory factors and parameters of oxidative stress are associated with the development of diabetes complications. This study was designed to determine the beneficial effects of synbiotic Gaz on insulin resistance, inflammatory factor and oxidative stress in patients with type 2 diabetes.
Materials and Methods: This randomized crossover double-blinded controlled clinical trial was performed among 62 diabetic patients aged 35-70 y. Subjects were randomly assigned to consume of either the synbiotic (n=62) or control Gaz (n=62) for 6 weeks. A 3-week washout period considered. The synbiotic Gaz was consisted of a probiotic viable and heat-resistance strain Lactobacillus sporogenes (1×107 CFU), 0.04 g inulin and 0.05 g stevia per 1 g as sweeteners' substances. Control Gaz (the same substance without probiotic bacteria and prebiotic inulin) was. Patients were received synbiotic and control foods in a 7 g package thrice a day. Fasting blood samples were taken at baseline and after 6-week intervention to measure insulin resistance, hs-CRP and biomarkers of oxidative stress.
Results: Consumption of synbiotic Gaz, compared with control, resulted in a significant decrease in serum insulin (p=0.02) and hs-CRP levels (p=0.008). Supplementation with synbiotic Gaz led also to a significant increase in plasma total glutathione (p<0.0001) compared to the control.
Conclusion: In conclusion, consumption of synbiotic Gaz for 6 weeks resulted in decreased levels of serum insulin, hs-CRP and increased levels of plasma total glutathione.
Mohammad Reza Massoudinejad, Ashraf Mazaheri Tehrani, Farshid Ghanbari, Simindokht Mirshafian,
Volume 17, Issue 3 (6-2014)
Abstract
Background: The conventional methods of water disinfection are chemical process, ozonation, UV radiation, membrane processes and etc. In recent years, electrolysis method has been considered that is a green process with high efficiency and not by-products. The aim of study is evaluation of efficiency of the electrolysis process with continuous flow in the disinfection of water contaminated with fecal coliform.
Materials and Methods: This study is a Descriptive - analytical study. The samples are prepared in three groups by adding domestic wastewater, manure and E.Coli colonies to distilled water. The prepared samples were introduced to continuous electrochemical reactor. The removal efficiency of electrolysis process was investigated in different conditions which include electrode material (copper and graphite compressed), reaction time (40, 50, 60 and 70 minutes), voltage 48V, distance of electrode 5 cm and the initial pH 7.
Results: The results indicate that removal efficiency depends on source of pollutant, reaction time, and type of electrode. Also the optimal efficiency for E.Coli colonies achieved in electrolysis instrument was as follows: electrode material = copper electrode, distance of electrode=5cm, applied voltage= 48V and reaction time=70 minute. Under these conditions removal efficiency was obtained 99%. No significant changes in pH, TDS and EC in different times and coliform bacteria were not created by changing the source.
Conclusion: According to the results of this study, using the electrolysis process with continuous flow, as a convenient method with high performance and environmentally, suggest for the disin fecting the water contaminated with fecal Coliform.
Neda Soleimani, Ashraf Mohabati Mobares, Fatemeh Atyabi,
Volume 18, Issue 1 (4-2015)
Abstract
Background: The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a protective antigen and a major virulence factor of this bacteria. Stimulating the immune system for helicobacter infection treatment could have an important role. The aim of study is to assess the effect of recombinant Neutrophil activating protein (Hp-NapA) of helicobacter pylori on proliferation and viability of peritoneal macrophages from BALB/c mice.
Materials and Methods: In this experimental study, recombinant Hp-NapA of helicobacter pylori was produced in vitro. Mice peritoneal macrophages were purified and cultured. Different concentrations of recombinant Hp-NapA was used for macrophages stimulation. MTT assay was performed to assess the viability and proliferation of macrophages.
Results: The results elucidated that the increasing effect of stimulation with recombinant Hp-NapA was significant at the dose of 30 µg/ml (p=0.01). The rate of viabitity was significantly higher than control group at the doses of 30 and 60 µg/ml and in the concurrency series of recombinant protein with lipopolysaccharid, there was a statistically significarit increase in proliferation at just these doses.
Conclusion: According to our findings, recombinant Hp-NapA has a positive effect on proliferation, viability and function of peritoneal macrophages. Therefore, it is proposed that recombinant Hp-NapA can be studied as an immunomodulator for immunotherapy.
Masoud Motalleby, Ashraf Mazaheri, Mohadeseh Mosayebi, Sayyed Mehdi Takhtfiroozeh,
Volume 18, Issue 5 (8-2015)
Abstract
Background: The air pollutants such as CO, SO2, NO2, O3, and particulate matters have harmful effects on public health. Determination of the actual concentration of the pollutants and description of air quantity and quality contents in comparison of standard conditions and timely informing people to regulate control programs is essential. Kashan is exposed to the winds contain-ing the suspended particulate matters due to the proximity of the desert. Moreover, the growth of population, factories and industries in the city are artifical resources of the air pollution. Hence, assessment and monitoring of air pollution standard condition in kashan is crucial.
Materials and Methods: In this cross-sectional and descriptive study, the concentration of CO, SO2, NO2, O3, and suspended particulate matters less than 10 microns (PM10) measured according to WHO standards in Panzdah-e-Khordad station of Kashan in 2011. The annual mean and maximum rates, the mean and maximum rate of summer and winter, and annual percentile 98%, determined for each pollutant and used in AirQ software. Then, the number of death and disease attributed to each pollutant was calculated.
Results: The results demonstrate that the cumulative number of deaths attributed to PM10, NO2, SO2, and O3 was 100, 22, 82, and 54, respectively.
Conclusion: In total, the suspended particulate matters have the most effects on death and disease resulted from the air pollution. Hence, managing the resources of particulate matters and SO2 pollutants has many effects on reducing the adverse health effects of air pollution in Kashan.
Davarkhah Rabbani, Mohammad Reza Rezaeimofrad, Ashraf Mazaheri, Mohadeseh Mosayebi,
Volume 18, Issue 9 (12-2015)
Abstract
Background: The growth of population, improvement of quality of life and the development of industries have led to increase in the rate of urban and industrial waste. As the leachate of the waste has a lot of pollution, influences harmfully human health and the environment. Researches have shown that the advanced oxidation processes (AOPs) such as Fenton and Fenton-related processes can reduce chemical oxygen demand (COD) of the leachate effectively.
Materials and Methods: In this paper, the rate of decrease in the total suspended solids (TSS) of leachate from a composting facility in Isfahan was studied using electrochemical, Fenton and electro-Fenton processes. These processes were conducted at reaction times 0, 20, 40, and 60 minutes, with the currents of 0.5, 1 and 1.5A and hydrogen peroxide dosages 1000, 2000, and 3000 mg/L.
Results: In the three mentioned processes, the most TSS removal was observed at the first 40 minute of the reactions. Among the studied processes, the electro-Fenton removed up to 92.4% of the TSS and was recognized as the most effective method. Furthermore, electrochemical and Fenton removed 41.7% and 60.3% of the TSS, respectively.
Conclusion: Therefore, decreasing the TSS of leachate could change its qualities and reduce the leachate pollution and the adverse environmental effects.