Showing 9 results for Asghari
Keyvan Ghasami, Akram Asghari, Fereshteh Naranji, Kamran Moshfeghi, Babak Eshrati,
Volume 12, Issue 4 (2-2010)
Abstract
Background: Tension headaches are the most basic reasons for referring to physicians throughout the world. Iron anemia, on the other hand, is the most common type of anemia among women who are in productive age in the world. This study was done to investigate the relationship between vascular headaches and iron anemia and to see the effect of iron tablets administration on the treatment of these headaches in women who are in productive age. Materials and Methods: In this quasi-control study, 50 women in reproductive age who had iron anemia and vascular headaches, referring to the neurologic clinic of Vali-asr Hospital in Arak, were selected and treated with ferrous sulfate tablets for three months. For verifying the treatment, patients' hemoglobin was monitored after one month, and in case of any significant increases in this value, the patients discontinued participating in the study. The number of headache attacks and the number of analgesics used before, through and three months after beginning the administration of ferrous sulfate were noted for all of the patients. Results: The mean number of the headache attacks one month before treatment, during the treatment and three month after the treatment were 19.6±28 , 14.2±11.2 , 13.3±11.8, respectively (p=0.0001) . In addition, the mean number of used analgesics before the treatment, through the treatment and three month after the treatment were 30.1±14.1, 14.3±11.2, 13.1±16.1, respectively (p=0.0001). Conclusion: It seems that using iron tablets can be useful in treatment of vascular headaches.
Bahram Pourghassem Gargari, Fereshteh Aliasghari, Sousan Kolahi, Mohammad Asghari Jafarabadi, Elham Mirtaheri,
Volume 17, Issue 12 (3-2015)
Abstract
Background: Rheumatoid arthritis is an inflammatory disease. Hypertension could occur as a result of chronic inflammation in RA patients. Some evidence demonstrates anti-inflammatory effects of alpha-lipoic acid in inflammatory diseases. However, a limited number of studies have evaluated the effects of alpha-lipoic acid in rheumatoid arthritis. Therefore, the current study was designed to investigate the effects of alpha-lipoic acid supplementation on blood pressure and some inflammatory factors.
Materials and Methods: The present study was a randomized, double-blinded, placebo-controlled clinical trial in which 70 female patients aged 20–50 years were randomized to two groups to receive either alpha-lipoic acid (1200 mg/day) or placebo. The intervention duration was 8 weeks. Systolic and diastolic blood pressures were measured before and after the supplementation period. Also, C-reactive protein (CRP) and interleukin-6 (IL-6) were measured. Statistical analysis was done using SPSS13 software.
Results: 65 RA patients completed the trial. Systolic and diastolic blood pressure in alpha-lipoic acid group was significantly decreased in comparison with placebo group (p<0.05). But, CRP and IL-6 serum levels did not indicate any significant within- and between group changes.
Conclusion: In the present study, alpha-lipoic acid supplementation resulted in significant blood pressure reduction in rheumatoid arthritis participants.
Mahyar Nourian, Ali Mohammad Asgharian, Hamid Asadzadeh Aghdaei,
Volume 19, Issue 3 (6-2016)
Abstract
Background: Inflammatory bowel disease (IBD) includes two basic categories ulcerative colitis (UC) and Crohn's disease (CD) that the etiology of which remains unclear. Tumor necrosis factor alpha (TNFα) promoter polymorphisms are a good candidate for susceptibility to IBD as there is a significant relationship between them. The main aim of this study was to assess TNFα gene polymorphisms with IBD susceptibility at positions -1031in Iranian patients.
Materials and Methods: In this case-control study, were studied 101 patients with IBD (86 ulcerative colitis, 15 Crohn's disease) and 100 healthy controls were studied. PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Length Polymorphism) was used for determining of genotyping. In following, allele frequency and genotype distribution of polymorphism T> C in TNFα gene between the case and control groups were typed.
Results: The frequency of genotype TT, TC and CC among patients was 64.4%, 28.7% and 6.9% and in control group was 63%, 29% and 8%, respectively. Also, allele frequency T-1031 of TNFα gene in IBD patients was high, while there is no statistical significant(p>0.05).
Conclusion: There was no significant correlation between TNFα gene polymorphisms and susceptibility to IBD at position -1031. Our results showed that TNFα gene polymorphisms cannot be considered as a potential prognostic marker cause of IBD in Iranian population.
Nader Saeedi, Mohammadreza Rezvanfar, Mehdi Hadidi, Farvah Asgharizadeh Mahani, Mojtaba Ahmadlou,
Volume 19, Issue 6 (9-2016)
Abstract
Background: The renin-angiotensin system(RAS) has a major role in development of diabetic nephropathy and blocking of RAS by inhibitors and blocking of angiotesin receptors is standard treatment for preventing kidney disease and proteinuria. It is reported that VIT-D analogues are able to suppress renin exertion and improve proteinuria. The aim of this study is to evaluate the effect of VitD analogue (calitriol) on reducing proteinuria in patients with diabetic nephropathy.
Materials and Methods: In this clinical trial study, 132 eligible patients that had diabetic nephropathy and hadn’t vit D deficiency were selected. The patients were divided into two equal groups. First group received the combination of losartan 25mg twice daily and calcitriol 0.25mg and second group received losartan 25 mg twice daly alone for 3 months. The FBS, lipid profile, ESR-CRP BUN, Cr, HbA1c, Ca, P, and 24 hours urine protein were evaluated in all patients at beginning and end of study and the results were statistcally compared.
Results: The 24-hour urine protein in losartan and calitriol group was improved compared to losartan. This difference was statistically significant (p=0.003). As well as, in kidney function (BUN, Cr) in the losartan and calcitriol group compared to losartan alone was significantly improved(p<0.05).
Conclusion: Combination of calcitriol with angiotesin receptor blockers(ARBs) is more effective than ARBs alone in improvement of proteinuria and real function.
Saeid Kavoosian, Ali Mohammad Asgharian, Ramin Ataei ,
Volume 19, Issue 8 (11-2016)
Abstract
Abstract
Background: Osteoporosis is describesd as a disorder and skeletal disease that decrease bone strength and increases the risk of a bone fractures. Genetic factors have effect role in the progression of the osteoporosis. The aim of this study was to investigate the association between LRP4 gene polymorphism with osteoporosis in a population of postmenopausal women from north of Iran.
Materials and Methods: In this case-control study, 80 female patients with osteoporosis and 80 healthy females without osteoporosis with average age of 45-60 has been investigated. After DNA extraction from genome samples, polymorphism of LRP4 (rs4752947) gene have been investigated by PCR-RFLP method. Data were analyzed by SPSS software.
Results: Our results showed no significant relationship between polymorphism of LRP4(rs4752947) gene and the risk of osteoporosis disease in two patients and control groups. Also, AT genotype and TT genotype compared with AA genotype increased the chance of disease by 1379 and 3.5, respectively. In addition, TT alleles compared with AA alleles, increased the chance of osteoporosis up to 1.605 times.
Conclusion: Of course, more complementary studies considering other LRP4 gene subtypes with more individuals for better findings are needed.
Ali Azam Rajabian, Mohammad Javad Asghari Ebrahimabad, Hamidreza Aghamohammadian Sharbaf, Seyed Kazem Rasoolzadeh Tabatabaei,
Volume 25, Issue 3 (August & September 2022)
Abstract
Background and Aim There is almost no accurate information about the causes of body dysmorphic disorder. Many patients with body dysmorphic disorder who apply for plastic surgery show a negative response to these treatments and sometimes the symptoms get worse. The purpose of the present study was to investigate the causes of body dysmorphic disorder in women.
Methods & Materials The present research was a qualitative study with a content analysis type. Variables and categories were obtained by interviewing 15 experts and eight people with body dysmorphic disorder and reviewing 71 articles. Also, to diagnose body dysmorphic disorder, Yale Brown’s Practical Obsession Questionnaire was used in addition to the interviews. The sampling method in this research was purposive sampling. Data analysis was done in three stages: open, central, and selective coding. The validity of the components was checked by calculating the content analysis index.
Ethical Considerations In the research, before the interview, written consent was received regarding the specificity and confidentiality of the research (Code: IR.UM.REC.1401.105).
Results The influential factors in body dysmorphic disorder were: a. Cultural and social factors b. Psychological factors, and c. Biological factors.
Conclusion According to the obtained results, several factors play a role in the occurrence of body dysmorphic disorder, and their identification in different environments, cultures, and societies provides the possibility of developing preventive measures, and designing and developing a suitable treatment model. However, to increase the external validity of the research, it is suggested to conduct similar research in other societies.
Mr Abbas Bayat Asghari, Mr Javad Javaheri, Mr Alireza Manzari Tavakoli, Mr Hamid Mollayi Zarandi,
Volume 25, Issue 6 (February & March 2023)
Abstract
Introduction: The purpose of this study was to compare the effectiveness of cognitive-behavioral therapy and motivational interviewing on self-esteem in divorced women.
Methods: The current study was a semi-experimental pre-test and post-test design. The statistical population consisted of 260 divorced women aged 20 to 50. 60 women were selected based on the inclusion criteria and randomly assign to three groups of cognitive-behavioral therapy, motivational interview therapy and control group. The instrument of data collection was Rosenberg Self- Esteem Questionnaire. For the experimental groups, 12 sessions of 75 minutes were held. No intervention was done for the control group. Before the interventions and at the end of the study, people in all groups filled out the questionnaire. The data was analyzed using SPSS version 25 software and analysis of covariance (ANCOVA).
Results: There was a significant difference between the three groups of cognitive-behavioral therapy, motivational interview and the control group in the comparison of the mean score of self-esteem variables (P<0.05). Also, in the one-by-one comparison of the cognitive-behavioral therapy and motivational interview therapy groups with the control group, there was a significant difference in the post-test stage (P<0.05).
Ethical considerations: In this research, the principle of confidentiality, preservation of personal information and non-disclosure of the identity of the participants were ensured and it was reminded that the obtained information will only be used statistically.
Conclusions: The findings indicate that cognitive-behavioral therapy and motivational interviewing are effective in enhancing self-esteem in divorced women. It suggests that these two methods are used along with other psychological and pharmaceutical therapies for divorced women as a clinical intervention.
Dr Mehdi Asghari, Dr Gholamabbas Fallah Ghalhari, Dr Marzieh Abbasinia, Dr Farbod Ebadifard Azar, Dr Fahimeh Shakeri, Dr Mohammad Javad Ghanadzade, Mr Gholam Heidar Teimori, Dr Sanaz Karpasand, Dr Hossein Safari,
Volume 26, Issue 3 (August & September 2023)
Abstract
Introduction: One of the biggest environmental challenges of the 21st century is the phenomenon of climate change and global warming, which can cause numerous health problems. One significant health issue associated with climate change is the increase in the prevalence of heat stress, particularly in occupational encounters in hot outdoor environments. So this study aimed to predict and model temperature and humidity indices in the coming decades in a dry climate.
Methods: This study obtained daily atmospheric parameters, including minimum temperature, maximum temperature, and relative humidity of Kerman station, representing a dry climate, for a period of 30 years (1965 to 2005) from the meteorological organization. Modeling of these parameters and calculation of the Temperature and Humidity Index (THI) were performed using the atmospheric general circulation model HadGEM2-ES and the CORDEX dynamic microscaler model. Three different radiative forcing scenarios, including optimistic (RCP 2.6), intermediate (RCP 4.5), and pessimistic (RCP 8.5), were considered for the coming decades (three 30-year periods from 2011 to 2099). The Ethics Committe of Iran University of Medical Sciences (IUMS) approved the present study (Code: IR.IUMS.REC.1400.020).
Results: The results of the study showed an increasing trend for minimum and maximum temperature parameters in all three time periods using the three scenarios considered. Moreover, the increase in temperature in the decades of 2099-2071 was more pronounced compared to the previous decades. The results also demonstrated an increasing trend in the THI index based on all three scenarios. The average results obtained using these scenarios showed an increase of 2.11, 2.53, and 3.3 degrees Celsius, respectively, in this index until the end of the last century compared to the base decades.
Conclusions: Overall, the increase in temperature and the investigated THI index in the studied station, based on all three scenarios, will lead to changes in thermal comfort. Higher levels of thermal discomfort will not only occur in hot months and seasons but also in other seasons. Therefore, proper planning should be implemented to address the adverse effects of climate change on people's health.
Mehdi Asghari, Melika Azizi,
Volume 27, Issue 1 (3-2024)
Abstract
Lack of preparation for fires can lead to irreversible damage. Therefore, fire prevention is crucial in effectively managing this risk. It is essential to implement measures to address fire incidents. Fire safety in hospital is particularly critical due to factors like the presence of disabled individuals who may not be familiar with emergency exit points, as well as the specialized medical equipment present. Fires in hospitals can result in extensive harm, including injuries to staff and patients, a loss of trust in local authorities, and the subsequent failure to deliver adequate healthcare services. Adhering to fire safety principles and fundamentals can help mitigate the impact of fires in all locations, especially medical facilities.
