Acquired zinc deficiency in breast-fed-infants , particularly under six MO, of age is rare except in premature infant and acrodematitis entropathica. Our case in this essay seems that after a prolonged diarrhea due to E coli has got transient zinc deficiency, that with oral zinc sulfat shows prompt clinical response in 72 hours. Therefore ihtractable "diaper rash" in a full term or preterm breast-fed-infants or in a patient with prolonged diarrhea may be due to zinc, deficiency, a therapeutic trial of zinc in a patient with high index of suspicion of zinc deficiency is a reasonable and safe.
