Mahmoud Pedram , Mohammad Taha Jalali , Fazlolah Ahmadi Esfahani,
Volume 1, Issue 5 (Winter 1997)
Abstract
Serum concentration of lipoprotein(a) is a genetically determined. Independent risk factor for coronary artery disease. Different studies suggest a possible role for a antioxidant and free radicals in the rate of lipoprotein (a) synthesis. Patients suffering from chronic renal failure (CRF) are known to be less guarded against oxidative products in comparison with normal population. In order to investigate the pattern of lipoprotein (a) serum concentration in CRF group, 87 number of patients undergoing supportive hemodialysis was selected and their Lp(a) serum concentration were compared with a control group (n=100). The result shows a significant elevation of LP(a) serum concentration in the patients in comparison with the control group (p,0.05).
