Showing 5 results for Abiri
Nayere Baghcheghi, Hamidreza Koohestani, Akram Dabirian, Hamid Alavi Majd,
Volume 10, Issue 1 (3-2007)
Abstract
Introduction: The use of complementary and alternative therapy is increasing and touch is one of them but several studies have indicated that premature neonates hospitalized in neonatal intensive care unit receive very little touch. The purpose of this research was to determine the effect of touch on arterial blood oxygen saturation in neonates with respiratory distress syndrome. Materials and Methods: This is a clinical trial with repeated measures that was performed on 37 neonates with respiratory distress syndrome. An information record form was used for data collection. The information record form was consisted of two parts: demographic information and a table for recording oxygen saturations. Oxygen saturation was measured by Nelkor pulse oxy meter. Information was collected in 3 sequential days. Arterial blood oxygen saturation was controlled 5 minutes before touch, then samples undergone 5 minutes touch and then in 5 and 15 minute intervals arterial blood oxygen saturation was controlled again. Data was analyzed using repeated measure ANOVA. Results: Findings showed that in the first day, arterial blood oxygen saturation in 5 minutes before, and 5 and 15 minutes after touch were 95/67, 95/91, 96 respectively. In second day, arterial blood and oxygen saturation in 5 minutes before, and 5 and 15 minutes after touch were 95/72, 96/05, 96/08 respectively. In third day, arterial blood oxygen saturation in 5 minutes before, and 5 and 15 minutes after touch were 95/75, 96/16, 96/13 respectively. Arterial blood oxygen saturation in 5 and 15 minutes after touch were more than 5 minutes before touch in each 3 day(p<0.01). But there was no significant difference between 5 and 15 minutes after touch. Data analysis also showed no significant difference comparing arterial blood oxygen saturation in the 3 days. Conclusion: Findings suggested that premature neonates physiologically responded to touch. Nurses working in NICUs must be educated about the importance of touch in providing care for these neonates. Findings showed that touch is useful for premature neonates and this fact can be a start point for other investigations.
Seyed Mahmoud Tabatabaei, Amir Monfaredan, Nasrin Bargahi, Shahram Dabiri Oskuei,
Volume 15, Issue 4 (September 2012)
Abstract
Background: In addition to known environmental and acquired factors effective in cardiovascular diseases, polymorphisms of VKORC1 and CYP2C9 genes are identified as the main genetic factors involved in warfarin dosage requirement variations in these patients. With this approach, investigating the frequency of 1639 G>A in VKORC1 gene for determining the specific dosage required for each person was the main aim of this study. Materials and Methods: In this experimental study, peripheral blood samples were obtained from 200 patients with cardiovascular disorders in the northwestern areas of Iran (West and East Azarbayjan and Ardabil) and RFLP-PCR technique was used to determine the 1639G> A polymorphism of VKORC1. Results: Using Hardy-Weinberg law, polymorphism amounts of 1639G> A gene from VKORC1 in female and male patients with normal, heterozygote, and homozygote were determined 21.6%, 53.7%, 24.5% , and 22.3%, 60.6%, and 17.02% , respectively. Conclusion: VKORC1 genotyping is one of the important parameters that together with other confounding factors reduce the role of trial and error in patients with cardiovascular diseases. Genotypic variety and the high frequency of allele A in the studied population can justify varied responses to warfarin therapy and the importance of investigation before starting treatment with warfarin.
Yasamin Abdanankord, Hossein Dabiri, Hossein Goodarzi,
Volume 18, Issue 6 (9-2015)
Abstract
Background: Pseudomonas aeruginosa is one of the important causes of hospital infections septicemia, in patients hospitalized in burn ward and those with cystic fibrosis. Considering the PAPI-2 important role in bacteria pathogenesis, the aim of this study is to investigate the frequency of the encoding genes exoU and xerC as markers of PAPI-2 from isolated environmental and clinical samples.
Materials and Methods: In this descriptive study, 40 isolates from sewage of burn wound hospital and 30 from patients hospitalized in burn ward of the hospital covered by shahid Beheshti University, respectively. The frequency of PAPI-2 in both environmental and clinical strains was detected by using PCR and the primers exou and xerc.
Results: Of 40 studied environmental pseudominas aeruginosa strains that their genus and species were confirmed by chemical tests, 30 samples (75%) consisted of exoU gene and 32(80%) included xerC gene. Also, of 30 isolated strains of burn patients, 23 isolates(76.7%) contained both exoU and xerC gene. The results revealed a high prevalence of PAPI-2 (90%) between clincial and environmental samples of pseudomonas aeruginosa.
Conclusion: With due attention to the results, information reveal that the importance and prevalence of pathogenicity island type 2 were high in Iranian clinical and environmental Pseudomonas aeruginosa isolates. Also, considering all environmental isolates have at least one of genes, we should care about the risk of transporting pathogenic strains and find solutions to control it.
Maryam Doosti Mohajer, Hamid Pajavand, Ramin Abiri, Amirhooshang Alvandi,
Volume 20, Issue 9 (12-2017)
Abstract
Abstract
Background: Antibiotic resistance rates in E. coli are rapidly rising, especially with regard to fluoroquinolones. One of the mechanisms that lead to antibiotic resistance is efflux pumps. The aim of this study was phonotypic and genotypic analysis of efflux pump role in fluoroquinolones resistance of E. coli strains isolated from hospitalized patients in Kermanshah 2013.
Materials and Methods: In this cross-sectional study, 100 isolates of E. coli were collected from hospitalized patients from Kermanshah. All isolates were identified by standard biochemical tests. The antimicrobial susceptibility patterns were determined by disk diffusion method according to CLSI guidelines. The presence of Efflux pump genes was determined by a PCR method.
Results: The rates of resistance to Ceftazidime, Nalidixic Acid, Ciprofloxacin, Norfloxacin, Ofloxacin, Gentamicin, and Tetracycline were 73%, 67%, 55%, 54%, 45%, 38%, and 24%, respectively. According to the results of PCR test, of 100 E. coli isolates, 99% of isolates were positive for acrA, 98% for acrB, 95% for acrE, 98% for acrF, 94% for mdfA, 96% for norE, and 96% for tolC.
Conclusion: In Strains with positive gene acrA, acrB, acrA, acrB, tolC, mdfA, norE, the presence of efflux pump inhibitor reduced the amount of resistance to antibiotics. So, efflux pumps are important in antibiotic resistance.
Mohammad Rahmanian, Ali Reza Kamali, Hadi Mosalanezhad, Mahdi Foroughian, Navid Kalani, Naser Hatami, Mohammad Heidarnezhad, Esmaeal Rayatdoost, Samaneh Abiri,
Volume 23, Issue 5 (December & January - Special Issue on COVID-19 2020)
Abstract
Background and Aim: The recent Coronavirus Disease 2019 (COVID-19) outbreak has caused a lot of stress and anxiety in the world. Given that health care workers are at the forefront of fighting against COVID-19, they are the first to be exposed to this disease.
Methods & Materials: This is a descriptive cross-sectional study conducted on 402 medical and administrative staff working in hospitals and health centers affiliated to Jahrom University of Medical Sciences in 2020. Data collection tools were a demographic form and the Corona Disease Anxiety Scale (CDAS).
Ethical Considerations: This study was approved by the Vice-Chancellor for Research of Jahrom University of Medical Sciences (Code: IR.JUMS.REC.1399.046).
Results: The mean score of psychological symptoms of anxiety in the medical staff (46.91) was higher than in the administrative staff (42.63). Its physical symptoms were also higher in the clinical staff (12.80) compared to the administrative staff (10.94). There was a significant difference between the clinical and administrative staff in terms of anxiety (P=0.030).
Conclusion: Medical staff has higher psychological and physical symptoms of anxiety compared to the non-medical staff during the COVID-19 outbreak. Therefore, in order to reduce the anxiety of medical staff, health policymakers should take the necessary measures to take care of this group.
