Search published articles



Esmaeil Moshiri,
Volume 2, Issue 9 (3-1999)
Abstract

In a double bilnd randomized clinical trial, we studied the effect of diazepam in reducing of postoperative shivering in orthopedic patients in two groups: each group 50 patients .one group case and another control. Both group received fentanyl 1.5 mic/kg before induction of anesthesia. Patients in both group induced with nesdonal 5 mg/kg and the flaxedil the with hallotane 1.5% and oxygen 50% and N2050%. Ten minutes before end of operation we injected 2cc (10 mg) Diazepam into the case group and 2cc normal saline into the control group. After the injection, the shivering was observed, and recorded in questionnaire in 5, 10, 15, 20 and 25 minutes. On the basis of our results patients who have received Diazepam had less shivering than who received normal saline (p value , 0.005), so Diazepam can diminish postoperative shivering.

Shirin Pazouki,
Volume 3, Issue 1 (3-2000)
Abstract

Through a clinical trail, the effects of metoclopramide infusion compared with a placebo in order to assess the effectiveness of the medicine in Imam Khomeini and Vali-Asr hospitals of Tehran were brought under consideration in two groups, which passessed the necessary condition. Metoclopramide was prescribed as a bolus dose of 0.5m/Kg and then its infusion as 1m/Kg at 6 hours intervals, while the control group were only received normal saline for the same duration. Sampling was simple and there was no distinctions between the groups. In review of the postoperative pain the patients were precisely looked after for the next 24 hours of the operation by the ward nurses and if it necessitated narcotics were prescribed. The analysis of the results manifested that the metoclopramide infusion doesn’t lessen the necessity of using narcotics significantly (P=0.174), but it can increase the analgesic effect of narcotics in case group compared with the control group. (P=0.0344) and the intervals of needing narcotics have been more (P=0.0223). In addition, the control group had considerably less incidence of nausea comparing with case group (P=0.0094) and the degree of vomiting was nearly less too (P=0.157). The sedation degree was significantly higher than the case group (P=0.033). No any other side effects of narcotics or metoclopramide, including itching, restlessness and tremor were observed. Metoclopramide infusion can increase the analgestic effects of narcotics. Drugs and significantly lessens the need for narcotics during the first hours of postoperation, Moreover it reduces the incidence problems arising from the site of incision and prescription of narcotics with high dose can be dangerous.

Shaabanali Alizadeh, Masoome Kalantari, Khadije Ahrari,
Volume 12, Issue 1 (5-2009)
Abstract

Background: Hydatid cyst, a parasite disease, can involve liver more than other organs. The most serious complication of the cyst is rupture which may spread out to biliary duct, hollow organ, or abdominal cavity directly. Elective treatment is emergent surgery. Case: A 28 rural woman referring with abdominal pain, nausea and vomiting due to car accident. Abnormal findings consisted of: abdominal distention, reduction of bowel sounds, tenderness and generalized guarding and hive lesions in the anterior chest wall, upper abdomen, and both forearms. In sonography, a lot of free liquid in abdominal and pelvic cavity, and three hetroechoic masses in the right lobe of the liver were reported. Four days after abdominal surgery the patient was discharged with Albendazole order. Conclusion: Intra-abdominal rupture of hydatid cyst is the most serious that due to trauma complication and elective treatment is emergency surgery.
Shabanali Alizadeh, Kamran Moshfeghi, Mssoumeh Kalantari, Khadijeh Ebrahimi,
Volume 12, Issue 4 (2-2010)
Abstract

Background: The existence of estrogen and progesterone receptors, p53, human epidermal receptor-2(HER-2) and cathepsin-D are among the prognostic markers for breast cancer. In this study, we investigated the relationship between these factors and lymph-node involvement. Materials and Methods: In this case-control analytic study, 105 patients with breast cancer were investigated. After detecting breast mass, surgical biopsy was done and the status of the estrogen and progesterone receptors, p53, HER-2, and cathepsin-D were studied. Collected data were registered in a checklist and were subjected to analysis. Results: There was no relationship between lymph-node involvement and estrogen and progesterone receptors, p53, cathepsin-D and HER-2. Conclusion: In order to get more precise results about hormonal receptors, p53, HER-2 and cathespin-D, a similar research with a larger sample size over a longer period of time is needed.
Ali Akbar Abdollahi, Kadije Yazdi, Naseer Behnampur, Mane Neyaze,
Volume 13, Issue 4 (1-2011)
Abstract

Background: Postoperative ileus after appendectomy causes gas storage, distention, nausea, vomiting, and even pain. Gum chewing is one of the ways that can reduce the duration of temporary ileus. The aim of this study is to determine the effect of gum chewing on bowel movements following appendectomy. Materials and Methods: This randomized double-blind clinical trial was done on 46 patients undergoing appendectomy that were divided into equal treatment and control groups. The treatment group chewed gum three times, each time for 20 minutes, 4, 10 , and 18 hours after recovery from anesthesia. The control group, however, did not receive any special treatments. The bowel sounds were monitored every two hours using stethoscope. Also, through running interviews with two hour intervals, data were collected regarding the first passage of flatus and defecation. Data were analyzed through SPSS and t-test. Results: On average, the first bowel sounds in treatment and control groups were, respectively, heard at 2.08±0.41 and 3.13±1.45 hours, whereas gas passage in treatment and control groups was reported at 26.8±14.59 and 50.08±13.92 hours, respectively. Also, the first defecation in the treatment group occurred at 18.91±10.77 hour but in the control group this happened at 29.21±12.11 hour. Based on these observations, a significant difference was seen between the two groups in terms of the test results (p=0.002). Conclusion: The findings of this study showed that chewing gum can help bowel movements after appendectomy.
Mahmood Amini, Seid Alireza Hosseini, Yahya Jand, Tooraj Zandbaf, Babak Eshrati, Shabanali Alizadeh, Ghasem Mosayebi, Ali Ghazavi, Ali Cyrus,
Volume 13, Issue 4 (1-2011)
Abstract

Background: Nowadays, the use of inflammatory biomarkers in the diagnosis of appendicitis is on the rise. On the other hand, the role of oxygen free radicals in various inflammatory states has been verified. Noticing the high prevalence of negative appendectomy (9.3-22.2%), the aim of this study was to investigate the level of blood total antioxidant capacity (TAC) as a biomarker for early diagnosis of acute appendicitis. Materials and Methods: In this prospective analytical trial, over a one-year period, 407 patients, with preoperative diagnosis of acute appendicitis who had undergone operation, were studied. After measuring the TAC level, data were analyzed through the analytic ROC curve and parametric mean comparison tests. Results: Of all the patients, 298 were identified with appendicitis. TAC levels in adult female and male groups were respectively 663.9±164.75 and 752.58±167.37 µm/L which revealed a significant difference (p<0.0001). Also, in children, the mean of TAC level in perforated appendicitis sub-group was significantly greater than those in gangrenous and suppurative groups. Conclusion: TAC level can be used as a predictive factor for the diagnosis of perforated appendicitis in children however, it cannot be used as a biomarker for the diagnosis of appendicitis. Because of the significant difference existing between the level of TAC in male and female patients, further studies are suggested to investigate the level of inflammatory biomarkers with respect to menstrual cycle in women.
Mahmood Amini, Tooraj Zandbaf, Shabanali Alizadeh, Yahya Jand, Seid Alireza Hosseini, Babak Eshrati, Ali Cyrus, Hamideh Amini,
Volume 14, Issue 1 (3-2011)
Abstract

Background: Diagnosis of acute appendicitis is one of the challenges that surgeons face in the emergency ward. Although Alvarado score has been recommended in the diagnosis of acute appendicitis, this criterion has some limitations in terms of age, sex, and race. The aim of this study was to evaluate the effectiveness of Alvarado score in the diagnosis of acute appendicitis based on the age and gender. Materials and Methods: In this cross-sectional study, 407 patients who underwent operation with the preoperative diagnosis of acute appendicitis from June 2008 to August 2009 were included in the study. The patients’ data were recorded by the investigators. The data were compared by parametric tests. The sensitivity and specificity were determined by the optimal cut-off point on ROC curve using MedCalc software version 10.2.0.0. Results: The optimal cut-off point for women was lower than men (6 and 7, respectively). The rate of negative appendectomy in the group with Alvarado scores 9 and 10 was 11.8%, while the negative appendectomy rate in the other two groups with Alvarado scores 7 and 8 and 5 and 6 were 29.9% and 52.8%, respectively. Conclusion: The diagnostic value of Alvarado score of 8 and less in physical examination is lower than the abdominal tenderness exam alone. Also, the cut-off point for the diagnosis of acute appendicitis in women should be considered lower than that in men. On the other hand, the cut-off point in adolescents and children is higher than adults.
Samane Abedi Dost, Majid Poya, Mohammad Shafe Shakouri,
Volume 14, Issue 2 (5-2011)
Abstract

Background: Hemorrhoidectomy is the basis of treatment for grades three and four hemorrhoid. One of the major post hemorrhoidectomy problems is pain that is usually due to the spasm of the internal sphincter. There are different methods for the management of postoperative hemorrhoidectomy pain. The aim of this study was to investigate the effect of sphincterotomy on post hemorrhoidectomy pain. Materials and Methods: This interventional clinical trial was conducted on 60 patients with 3rd and 4th grade hemorrhoid who had randomly been divided into hemorrhoidectomy and hemorrhoidectomy combined with sphincterotomy groups. The degree of pain was measured on visual analogue scale (VAS) and analyzed through Mann-Whitney, Friedman, and Chi square tests via SPSS version 14. Results: In terms of reduction in pain with sphincterotomy, there was a significant relationship between the two groups on the first, second, and fifth postoperative days (P=0.001). On the third and sixth postoperative days, a significant relationship was observed between the two groups (P=0.001). Days four and seven also indicated a significant relationship between the two groups (P=0.002). However, there were not any significant relationships between the two groups in terms of urinary and fecal incontinence and gas retention (P>0.05). A significant relationship existed between the two groups in terms of reduction in the need for sedation (P=0.006). Conclusion: Lateral internal sphincterotomy combined with hemorrhoidectomy can reduce the patients’ post hemorrhoidectomy pain and can reduce the use of analgesics, but it does not have any significant influences on the incidence of urinary retention and bleeding after the first defecation and does not increase the risk of fecal and gas incontinence in comparison with the hemorrhoidectomy group.
Mahmood Reza Baghinya, Davood Gudarzi,
Volume 14, Issue 5 (11-2011)
Abstract

Background: Transitional cell carcinoma is the most common bladder tumor that can be treated by surgery, BCG instillation, chemotherapy, and radiotherapy. This study deals with urethral squamous cell carcinoma (SCC) in a patient with history of transurethral resection (TUR-T) of bladder transitional cell carcinoma treated by BCG instillation. Case: A 68-year-old man was admitted with gross hematuria, lateral prostatic lobe kissing, and a pedunculated 2×3mm mass in bladder in cystoscopy. He had undergone TUR-T and BCG instillation and had been followed regularly every 3 months with cystoscopy. In the follow up, 9 months later, several pedunculated tumors in penile urethra that were of SCC type were indicated in pathological analysis. Conclusion:: Since membranous urethra is the most common site and TCC is the most common type of urethral cancers in this site, SCC in penile urethra was unexpected. This could be because of chronic inflammation due to treatment and cystoscopic follow ups.
Shahin Fateh, Ali Ahmadabadi, Naser Keikhali, Hamid Reza H.seddigh, Majid Esfandiari,
Volume 14, Issue 6 (1-2012)
Abstract

Background: Localization of ectopic parathyroid glands is one of the most sophisticated challenges in endocrine surgery and there is considerable controversy regarding the suitable approach to localize ectopic parathyroid glands and indications for using different modalities. The failure of the first operation leads to pain, scar, and financial burden of the following operation. Case: The patient was a 39-year-old woman hospitalized with hematuria as the main complaint and noticing the presentation of hypercalcemia in the initial tests underwent more thorough examination. Ultrasonography and 99mTc sestamibi scan helped us to localize the ectopic parathyroid gland in an anterior mediastinum and treat the patient in a one stage operation. Conclusion: Paying careful attention to the symptoms and signs, considering all differential diagnoses, and using appropriate diagnostic methods can be helpful in the diagnosis of rare syndromes.
Shahin Fateh, Mohamd Reza Mamaghani, Ghasem Mosayebi,
Volume 15, Issue 1 (4-2012)
Abstract

Background: Because of high mortality and morbidity of severe acute pancreatitis (AP) and its increasing incidence in recent years, early detection of severity of AP is very important. Since interleukin (IL) rapidly responds to body temperature changes, this study was done to examine the relationship between blood levels of interleukin 15 and 17 and severity of acute pancreatitis. Materials and Methods: In this cross-sectional study, 52 patients with AP were studied. For all patients, paraclinical information, Ranson criteria, and APACHE-II were completed. Serum interleukin 15 and 17 levels were measured by ELISA method. Then the relationship between them and AP severity was determined based on Ranson criteria and APACHE-II. Results: In this study, 36.5% of the patients were male and 63.5% were female and the mean age was 61.06 years. The serum level of IL-17 was negatively correlated with the severity of AP based on Ranson criteria (p=0.021, r= -0.319). ROC curve showed significant values for blood level of IL-15 and CRP in AP diagnosis. Sensitivities were 92.3% and 78.8% and specificities were 40% and 48%, respectively. Conclusion: Based on Ranson criteria, the role of serum level of IL-17 as an unknown factor was seen significant in determining the severity of AP. However, the diagnostic value of serum IL-15 should also be verified with further studies.
Mahmood Amini, Ali Ahmadabadi, Yahya Jand, Ghasem Mosayebi, Ali Ghazavi ,
Volume 15, Issue 2 (6-2012)
Abstract

Background: Acute pancreatitis is a common cause of abdominal pain, without any characteristic signs, symptoms, or a gold standard diagnostic modality. The purpose of this study was to evaluate the diagnostic value of urine trypsinogen-2 strip test in acute pancreatitis. Materials and Methods: In this cross-sectional study, 76 patients with abdominal pain suspected to acute pancreatitis who were admitted to the Emergency ward of Valiasr Hospital, Arak, were evaluated. In 46 patients, acute pancreatitis was confirmed (pancreatitis group), whereas in 28 patients, acute pancreatitis was ruled out (control group). In both groups serum levels of amylase, lipase, CRP, and urine trypsinogen-2 were measured by quantitative and qualitative methods. Sensitivity and specificity of the tests were determined and data were analyzed using SPSS software. Results: Urine trypsinogen-2 dipstick was positive in 36 of the 45 patients in the pancreatitis group (sensitivity: 80%) and in 2 of the 28 patients in the control group (specificity: 92.8%). Urine trypsinogen-2 ELISA test was positive in 41 of the 45 patients in the pancreatitis group (sensitivity: 91.1%) and in 4 of the 28 patients in the control group (specificity: 89%). Amylase sensitivity and specificity were equal to 82.6% and 75%, respectively. Lipase sensitivity and specificity were 76% and 85.7%, respectively. Conclusion: Urine trypsinogen-2 dipstick can be used to differentiate acute pancreatitis from other causes of abdominal pain. This rapid, easy-to-use, and accurate test can be used in emergency wards and primary health care units with limited diagnostic facilities.
Shaban Ali Alizadeh, Abolfazl Fatehi, Yahya Jand, Ghasem Mosayebi, Mohammad Rafiei,
Volume 15, Issue 2 (6-2012)
Abstract

Background: Several studies have demonstrated that the levels of inflammatory markers in healthy women are under the influence of menstrual cycle changes. The aim of this study was to compare blood levels of inflammatory markers in women with appendicitis in different phases of menstrual cycle. Materials and Methods: In this case-control study, 70 female and 12 male patients with appendicitis, and 61 healthy women were enrolled based on inclusion and exclusion criteria. Inflammatory markers, such as leukocyte count, CRP, ESR, and TNF-α were measured and compared using student t-test and one-way ANOVA based on different phases of menstrual cycle. Results: There were no significant changes in the ESR, CRP, and TNF-α concentrations and the number of peripheral blood leukocytes in different phases of the menstrual cycle in women with appendicitis. The mean number of leukocytes and CRP concentrations were significantly higher in patients with appendicitis compared with the control group. Conclusion: The findings show that there are not significant differences in the inflammatory markers in women with appendicitis during the different phases of menstrual cycles. It seems that day to day variation of sexual hormones in the menstrual cycle have led to very different conclusions about the change of inflammatory markers in different phases of menstrual cycle. Therefore, studies investigating inflammatory markers in women with acute appendicitis based on day of menstrual cycle, time of sampling in the day, and severity of appendicitis are suggested.
Reza Rezaei, Elaheh Ebrahimpoor, Amir Almasi-Hashiani ,
Volume 15, Issue 8 (1-2013)
Abstract

Background: Cataract is the leading cause of blindness and visual impairment. This study was performed to compare effects of two different incision types in cataract surgery on dry eye symptoms and diagnostic test values. Materials and Methods: In this clinical trial, 300 patients with cataract requiring phacoemulsification were studied. The patients were randomly divided into two operative method groups: limbal and clear corneal (anterior to the vascular arcade) incision. A complete set of ophthalmic examinations and tear related tests were done for all of the patients before surgery and one week and one month after surgery. The collected data were analyzed using SPSS and EPI-Info softwares. Results: Overall, 149 men and 151 women were enrolled in this study. On the first postoperative week, the means of symptoms, and TBUT and TMH values in both groups significantly decreased compared with the preoperative values. These values returned to the preoperative levels one month postoperatively which werein contrast to the changes of debri, PEE, corneal and conjnnctival staining. There were statistically significant differences between the results of pre- and post-operative symptoms, PEE, debri, TBUT, conjunctival and corneal staining. Except for TBUT, the results of these tests were not statistically different according to incision location. Conclusion: Phacoemulsification cataract surgery affects dry eye symptoms and diagnostic test values. In addition, except for TBUT, the location of incision had no effect on other test results and symptoms.
Gholam Reza Noori, Naser Keykhali,
Volume 15, Issue 9 (2-2013)
Abstract

Background: Central venous catheterization (CVC) is a common procedure associated with various side effects such as pneumothorax. Recently, the routine post-catheterization chest X-ray has been challenged. The aim of the present study was to design a scoring system for selecting patients requiring radiography after CVC procedure. Materials and Methods: In this cross-sectional study, 210 patients requiring CVC were enrolled in the study and pneumothorax potential risk factors, including body mass index>30, history of neck or chest surgery, emphysematous disease, history of catheterization, number of punctures, inappropriate position during CVC, and treatment with ventilator were recorded. Finally, chest radiography and clinical signs before and after CVC were compared and scoring system sensitivity and specificity were determined. Results: Incidence of pneumothorax was 5.24%. The number of punctures and patient's position and history of catheterization showed significant associations with pneumothorax development (p<0.001). Pneumothorax incidence in patients with score> 4 was 80% which was significantly higher than patients with score<4 (OR: 174.2, p<0.001). Sensitivity and specificity of using the scoring system at cut-off score> 2 were 81.8% and 87.9%, respectively. Conclusion: The results of this study showed that pneumothorax development risk is very low in patients with score<2 and there is no need for post CVC routine chest X-ray. However, in patients with score>4, pneumothorax development risk is high and it seems that chest radiography with close intervals even more than one time is necessary. Further studies are recommended to validate the proposed scoring system.
Ahmad Sarvarian,
Volume 16, Issue 1 (4-2013)
Abstract

Background: For calculating intraocular lens (IOL) power required for cataract surgery, ultrasonic biometry is used and the axial length of the eye is the most important error in this estimation. Therefore, the aim of this study is to evaluate the final refractive power based on the axis length of the eye in patients undergoing phacoemulsification cataract surgery.

Materials and Methods: In this cross-sectional study, from June 2010 till December 2011, 446 eyes which underwent phacoemulsification cataract surgery were investigated. Biometry was performed before cataract surgery to achieve emmetropia in all eyes. Based on the axis length of the eye, patients were classified into four groups: less than 22 mm, 22-24.5 mm, 24.5-26 mm, and more than 26 mm.

Results: There was not a significant difference in mean absolute value of final refractive power deviation from zero. The highest amount of mean absolute value of final refractive power deviation from zero was in myopia group which was equal to 1.52±1.17 diopter. However, there was not a significant difference in the amounts of mean absolute value of final refractive power deviation from zero according to axial length of the eye (p=0.081).

Conclusion: With increases in axial length of the eye, intraocular lens power calculation decreases, but the absolute difference of means is not significant in two apparatuses.


Jamal Falahati, Rahmatollah Jadidi,
Volume 16, Issue 2 (5-2013)
Abstract

Background: Endophthalmitis is the most important complication after cataract surgery which its incidence can lead to severe loss of vision or even loss of vision therefore, methods of prevention are very important. This study investigated the influence of vancomycin consumption during cataract surgery on prevention of endophthalmitis.

Materials and Methods: In this experimental study, the study population included patients of cataract surgery that were admitted to Amir Kabir Hospital. The patients were randomly assigned to two groups: with and without receiveing vancomycin in serum. Demographic characteristics of the patients before surgery and incidence of endophthalmitis with the examination until two weeks after surgery were recorded. To compare the frequency (incidence) of infection, endophthalmitis in two groups, Fisher's exact test and X2 test were used.

Results: Of the 1281 patients, 539 were administered vancomycin in serum. The examination after two weeks indicated that 3 (0.23%) patients developed endophthalmitis. Of these, 2 (0.16%) patients belonged to the group without vancomycin and 1(0.07%) patient belonged to the group receiving vancomycin. Fisher's exact test did not show any significant differences between the groups receiving vancomycin and the control group in the prevalence of endophthalmitis.

Conclusion: Although the relative frequency of endophthalmitis in patients without receiving vancomycin was further than control group, the difference was not statistically significant. Thus, adding a drop of vancomycine was not effective in prevention of endophthalmitis and the causes should be sought in other cases.


Alireza Mohammadi, Mohsen Dalvandi, Hossein Sarmadian, Mohammad Khalili,
Volume 16, Issue 5 (8-2013)
Abstract

Background: Hydatid disease is a common infection caused by Echinococcus granulosus. Cerebral involvement is very rare and only occurs in 2% of all hydatidosis in endemic areas. We report a case of primary multiple cerebral hydatid cysts in a 23 years old patient. Case: A 23 years old female was admitted in our emergency ward with primary generalized tonic colonic seizure, left body and face hemiparesis and history of headache in last two months. Contrast enhanced CT and MRI showed a big well-defined, rounded, cystic lesion in the motor strip of right temporo-parietal region with mass effect causing midline shift which was diagnostic for brain hydatid cyst and several smaller cysts. There was no evidence of other organs involvement. The patient underwent the brain surgery. A big hydatid cyst (10cm in diameter) and some others adhering to brain parenchyma in different sizes were evacuated completely and without rupture using Dowling method. Patient received albendazole 400mg/two times a day for 2 months too. There was no cyst in patient’s MRI study in two years follow up.

Conclusion: Though low incidence, primary multiple cerebral hydatid cysts should be considered in endemic area using brain CT and MRI. Surgery is standard treatment of the disease.


Mostafa Hosseini, Rahman Ghafari, Sima Karbalaei Esmaeili,
Volume 16, Issue 8 (11-2013)
Abstract

Background: Monitoring of facial nerve function during surgery help surgeons to preserve the nerve during parotid gland surgery. EMG is currently the standard method for monitoring, however, the rates of facial nerve paresis and paralyses are 68-18% and 3%, respectively. The disadvantages of this method are its cost and lack of access to it everywhere. Unipolar alternating electric current stimulation of the facial nerve causes contraction of the muscles and the nerves, and the damage can be avoided.

Materials and Methods: In this study, patients in the years 1388 to 1390 using monopolar electrocautery was undergoing parotidectomy and one month after surgery, the facial nerve injury were examined. During the study period, twenty patients had undergone total or superficial parotid gland resection and one excluded due to facial nerve involvement before surgery.

Results: In this study, 19 patients were studied. The mean age of patients participating in this study, 43.1 ± 13.9 years and 63.2% of them (12 cases) were female. A temporary palsy (5.4%) was observed and there was no paralysis.

Conclusion: Due to its availability and low cost, using electrocautery devices compared with standard facial nerve monitoring, EMG, is beneficial and the treatment results are also satisfactory.


Shahin Fateh, Mohamad Behgam Shadmehr,
Volume 16, Issue 12 (3-2014)
Abstract

Background: Thymus is essential in creating some of the disorders and diseases. Treatment of these disorders (particularly tumors and myasthenia gravis) is possible with complete removal of the thymus.

Materials and Methods: In this retrospective study over a period of eleven years, all case of thymectomy performed at the Department of Thoracic Surgery of shahid Beheshti University has investigated. Variables examined included age, sex, primary diagnosis, surgical technique, complications and results of surgery.

Results: The total number of patients was 50 (46% male and 54% female) with a mean age of 85.14 ± 46.41 years. Primary diagnosis was myasthenia gravis in 40% of patients and thymoma in 42% of them. Myasthenic symptom was the most common presenting symptom (50%). Radical thymectomy surgery was performed in 64% of patients. Fever and atelectasis (10%) and respiratory failure (12%) were the most common postoperative complication and mortality rate was 4%. Thymoma (64%) and thymus hyperplasia (20%) were the most frequent pathology. Clinical symptoms were gone or greatly reduced in 40% of patients. The majority of them had a primary diagnosis of myasthenia gravis (36%). 50% of patients have been followed up. The mean follow-up time in these patients is 32.20 ± 36.41 months.

Conclusion: Thymectomy surgery with low morbidity and mortality, provides the possibility of treatment of thymic lesions. Especially Thymoma and Myasthenia Gravis



Page 1 from 2    
First
Previous
1
 

© 2025 CC BY-NC 4.0 | Journal of Arak University of Medical Sciences

Designed & Developed by : Yektaweb