Journal of Arak University of Medical Sciences

The Effect of A Period of Resistance Training and Melatonin Supplementation on Sexual Hormone Levels, Pain Intensity, and Sleep Quality in Primary Dysmenorrhea Girls

Amene Barjaste Yazdi

Introduction: The purpose of this research was to investigate the effect of a period of resistance training and melatonin consumption on sex hormone levels, pain intensity, and sleep quality in girls with primary dysmenorrhea.
Methods: For this purpose, 60 girls with moderate primary dysmenorrhea disorder (score 4-7) were randomly placed in 4 groups: resistance training + melatonin, resistance training + placebo, melatonin supplement group, and control group. Pain intensity, and sleep quality were assessed by the McGill questionnaire, and the Pittsburgh questionnaire respectively. 10 mg of melatonin was taken daily in two 5 mg capsules and the placebo group received the same amount of carbohydrates in the same capsule. Weight training, three days a week for eight weeks. This circuit exercise training was in 9 stations and with a maximum of 10-12 repetitions at 30-65% of a maximum repetition in each station. Each set and repetition was separated by 2-3 minutes and 90 seconds of rest, respectively. The blood sample was taken in the morning, fasting and 5 cc from the brachial vein from the left hand while sitting in the sitting position, and was taken by special kits. Data were analyzed by ANOVA with repeated measures and Bonferroni post hoc test at level P<0.05. All experimental procedures were approved by the Ethics committee of the Sport Sciences Research Institute of Iran (Code: ID IR.IAU.NEYSHABUR.REC.1401.008), Clinical Trial (Code: ID IRCT20230703058653N1) from the Iran Clinical Registration Center and were conducted under the Declaration of Helsinki.
Results: A significant increase in Estrogen (P<0.001) and progesterone (P<0.001) levels in the exercise + supplement group compared to all groups, and in the exercise + placebo group and the supplement group compared to the placebo group was reported. Also, The decrease in Pain intensity (P<0.001) and sleep quality (A decrease in the sleep score means an increase in the sleep quality in the output of the questionnaire) (P<0.001) in the supplement group compared to all groups and in the exercise + placebo group (P<0.05) and the exercise + supplement group compared to the placebo group showed a significant difference.
Conclusions: It seems that synergy of exercise and melatonin has affected the sex hormones level. Also, the melatonin probably helped to improve the sleep quality and pain intensity of the subjects through the adjustment of sex hormones following dysmenorrhea. Also, exercise probably has an effect on the pain intensity and sleep quality through the release of beta-endorphins and the effects of exercise on the menstrual cycle, although the finding are ambiguous.

The Effect of Hypnotherapy in Promotion Subjective Well-Being and Sleep Quality in People with Generalized Anxiety Disorder

Majid Baradaran

Introduction: Generalized anxiety disorder can be described as a debilitating disorder characterized by negative evaluation by others, internal shame, negative self-concept, as well as high levels of anxiety and avoidance in specific social and functional situations. The purpose of this study was to investigate the effective of hypnotherapy in promotion subjective well-being and sleep quality in people with generalized anxiety disorder.
Methods: This was a quasi-experimental study with pretest-posttest and a control group design and conducted on 40 persons who had generalized anxiety disorder in Rasht, Iran in 2023 and were randomly divided into two experimental and control groups (20 persons in each group). The hypnotherapy was conducted during 6 sessions in the experimental group, while the control group did not receive any treatment. The data were collected through the subjective well-being and sleep quality Inventory. Multivariate analysis of covariance was used to analyze the data. This study was approved by the Research Ethics Committee of Payame Noor University (Code: IR.PNU.REC.1402.070).
Results: The results indicated that hypnotherapy was effective on subjective well-being (F= 33.38, P=0.001) and sleep quality (F= 5.10, P=0.03) in people with generalized anxiety disorder; this method also increased their subjective well-being and sleep quality.
Conclusions: The based on the results of the present study, hypnotherapy is effective in promotion subjective well-being and sleep quality in people with generalized anxiety disorder. It suggests that these method are used along with other psychological and pharmaceutical therapies for people with generalized anxiety disorder as a clinical intervention.

Investigation of Balance Disorders in Children; Effective Factors and Evaluations

Mahdi Panahian

Introduction: Vestibular defects, vertigo and Dizziness may lead to delay in postural control, lack of coordination, vertigo attacks and ultimately imbalance in children. In this systematic review, the factors affecting children's balance disorders and the effective tests for evaluating these children were investigated.
Methods: Valid articles were searched in Pubmed, Google Scholar, Elsevier databases between 2000 and 2023 using the keywords Balance, Vertigo, Dizziness, Vestibular, Children. In the present study, research articles, narrative reviews, systematic reviews, and meta-analysis related to the purpose of the study were evaluated and included in the study.
Results: In the present study, a total of 95 articles were found. By repetition, 13 articles were removed and 82 articles remained in the study. By examining the titles of these articles, 7 articles were removed because the title was not relevant to the purpose of this study and 9 articles were removed because the full text of the article was not relevant,then leaving 66 relevant articles. 8 studies were excluded from the present study due to exclusion criteria. Therefore, a total of 58 articles were included in this systematic review and effective factors in the occurrence of balance disorders and effective assessment in identifying these disorders were found.
Conclusions: Correct diagnosis of balance disorders in children using appropriate tests not only prevents unnecessary examinations and reduces parents' worries, but is also a prerequisite for successful treatment.

Frequency of Helicobacter Pylori and Its Histopathological Changes in Endoscopic Gastric Biopsy Specimens of Children in Urmia Shahid Motahari Hospital during March2019 to March 2022

Farzaneh Javanmard

Introduction: Helicobacter pylori is the most common bacterial infection in the world. Infection with this bacterium occurs during the first 5 years of life. The present study was conducted with the aim of investigating the frequency of Helicobacter pylori infection in children and the types of histopathological changes related to it in endoscopic gastric biopsy samples of children.
Methods: In this cross-sectional-descriptive study, the prevalence of Helicobacter pylori and histopathological findings of 169 children with it were examined in the gastric endoscopic biopsy samples that were sent to the pathology department of Shahid Motahari Hospital in Urmia during March 2019 to March 2022. This study was approved by Research Ethics committee of Urmia University of Medical Science, Urmia, Iran (code: IR.UMSU.REC.1400.227).
Results: Out of 571 examined patients, 169 children (29.5%) were infected with Helicobacter pylori, the most common histopathological lesion was chronic gastritis. 40.3% of patients had active chronic inflammation as a result of gastric biopsy. No significant relationship was found between Helicobacter pylori and children's gender (P=0.29), but a significant relationship was observed between Helicobacter pylori results and children's age (P=0.04). A significant relationship was also observed between Helicobacter pylori infection and the severity of chronic gastritis (P=0.0001).
Conclusions: Considering that the inflammatory histopathological changes of the stomach are seen in all children with Helicobacter pylori infection and in more than 40% of cases this inflammation is of an active type, it is necessary to pay special attention to the early diagnosis and treatment of this infection in children.

Comparison of the Effectiveness of Emotion-Focused Couple Therapy and Gottman Couple Therapy on Marital burnout and Depression in Infertile Couples

Ahmad Alipour

Introduction: Infertility is one of the bitter events of married life that has various psychological consequences. On the other hand, there are different treatments to reduce its psychological effects. The purpose of this research was to compare the effectiveness of emotion-focused couple therapy and Gottman couple therapy on marital burnout and depression in infertile couples.
Methods: The present research method was semi-experimental with a pre-test-post-test design with a control group. The statistical population of this research included infertile couples of Arak city in 1400, of which 54 couples were selected using available sampling method and 18 couples were randomly assigned in three groups (two experimental groups and one control group). The experimental intervention groups received emotion-focused couple therapy (10 sessions of 90 minutes) and Gottman couple therapy (10 sessions of 90 minutes), and the control group did not receive any intervention. After two months, the follow-up phase was done. In order to collect data, Beck's (1967) depression questionnaire and Pines' (1966) marital burnout questionnaire were used, and the data were analyzed using repeated measures analysis of variance and SPSS version 26 software. This research is approved by the ethics committee with the code IR.IAU.B.REC.1400.026. Also, the principles of confidentiality, written informed consent and destruction of participants' information have been observed.
Results: The results showed that Gottman couple therapy and emotion-focused couple therapy reduce couples' depression (2 = 0.265, P = 0.001, F = 18.94) and marital burnout (2 = 0.348, P = 0.001, F = 27.99) has been effective. In addition, emotion-focused couple therapy has been more effective in reducing couples' depression (p=0.033) and marital burnout (P=0.001) than Gottman's couple therapy.
Conclusions: According to the results of the research, it can be said that emotion-focused couple therapy is more effective than Gottman's couple therapy in reducing couples' depression and marital exhaustion. Therefore, couple therapists are advised to use emotion-focused couple therapy to improve depression and marital burnout of infertile couples.

The Effect of an Incremental Exercise Training Period on the Protein Expression of MMP-2 and MEF2C in Cardiac Muscle Tissue of Diabetic Wistar Rats

Mohammad Fathi

Introduction: Diabetes is a chronic and progressive metabolic disorder that causes heart tissue damage and changes in its protein levels. The purpose of this study was to investigate the effect of an incremental training period on MMP-2 and MEF2C protein in cardiac muscle tissue of diabetic Wistar rats.
Methods: In this experimental study, 40 male Wistar rats (age 10 weeks and average weight 245 ± 9.5 grams) were randomly divided into 4 groups of 10: diabetes-control (DC), diabetes-exercise (DT), healthy-exercise (HT) and healthy-control (HC). Intraperitoneal injection of streptozotocin (45 mg/kg) was used to cause diabetes. The training protocol was implemented for 6 weeks. 24 hours after the last training session, heart tissue was extracted. Western blot method was used to evaluate MMP-2 and MEF2C protein expression. Data analysis was done using one-way analysis of variance test.
Results: The results showed that diabetes causes a significant increase in MMP-2 protein expression levels and a significant decrease in MEF2C in the DC group compared to the HC group (P<0.05). although a period of increased training leads to a significant decrease in MMP-2 protein expression levels and a significant increase in MEF2C in the DT group compared to the DC group (P<0.05).
Conclusions: The findings of this research show that increasing aerobic exercise moderates the effects caused by diabetes in the expression of these two proteins, which seems to be a protective effect against cardiomyopathy changes caused by diabetes.

Investigate the Effectiveness of Training Coping Strategies with Stress on Distress Tolerance and Psychological Empowerment of Corona Nurses

roghayeh kiyani

Introduction: Adverse effects of Coronavirus on somatic and mental health is undeniable .nurses staff are exposed to risk of somatic and psychological effects because of continuous working time. The aim of this study was to investigate the effectiveness of training coping strategies with stress on distress tolerance and psychological empowerment of corona nurses in Khoy hospitals.
Methods: This research was applied in terms of purpose and quasi-experimental in terms of research method with pre-test – post-test design with control group And from the statistical population that included all nurses in the corona ward of Khoy hospitals in 2021 , 30 people were selected as the available sample. The subjects were randomly assigned into two groups (15 individuals in experimental group and 15 individuals in control group).In order to collect data, the Distress Tolerance Questionnaire and the Psychological Empowerment Questionnaire were used. The experimental group subjects participated in eight 90-minute sessions of training coping strategies with stress. Multivariate analysis of covariance was used to test the hypotheses. This study was approved by the Ethics Committee of Islamic Azad University of Tabriz (Code: REC.1400.135).
Results: The results showed that training coping strategies has increased distress tolerance and psychological empowerment in the post-test phase (P < 0.01).
Conclusions: According to the findings of the present study, it can be concluded that teaching coping strategies can be used as an effective method to improve stress tolerance and psychological empowerment of coronary nurses.

The Impact of Orem's Self-Care Model on the Anxiety Levels of Mothers with Children Who Have Febrile Convulsions

Elham Mohammadi

Introduction: Seizure due to fever is the most prevalent neurological condition in children aged 6 to 60 months. A child's seizure can cause significant distress for parents, particularly the mother. Anxiety control and the well-being of the mother are crucial elements in managing child seizures.
Methods: In this clinical trial, 70 mothers with children experiencing febrile convulsions were divided into two groups: an experimental group and a control group. The division was done using an available sampling method. The mothers in the experimental group received an intervention based on Orem's self-care model, while the mothers in the control group received the usual care. Mothers' anxiety was assessed one day after the child's hospitalization and again three weeks later using the Spielberger questionnaire. The data was analyzed using descriptive statistics, Chi-square test, Fisher's test, and analysis of covariance in SPSS software version 25.
Results: The study showed that after one day of hospitalization, the anxiety score of mothers in the test group was 101.68, compared to 106.25 in the control group. Three weeks later, the test group's anxiety score decreased to 68.97, while the control group's score was 96.34. Importantly, the decrease in the test group was statistically significant compared to the control group (P = 0.000).
Conclusions: Engaging in self-care activities results in a decrease in maternal anxiety. Hence, it is recommended to employ this approach when caring for children who are hospitalized.