Volume 14, Issue 2 (5-2011)
J Arak Uni Med Sci 2011, 14(2): 94-99 |
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Yadegari M, Khazaei M, Hamzavi Y, Toloei A R. Antifertility effects of Falcaria vulgaris in female rat. J Arak Uni Med Sci 2011; 14 (2) :94-99
URL: http://jams.arakmu.ac.ir/article-1-684-en.html
URL: http://jams.arakmu.ac.ir/article-1-684-en.html
1- Anatomical sciences Dep., Medical faculty,
2- Fertility and Infertility Research Center, Medical Faculty, University Ave. Shahid Shirodi Blovard, Kermanshah, Iran ,mkhazaei1345@yahoo.com
3- Kermanshah, Iran
2- Fertility and Infertility Research Center, Medical Faculty, University Ave. Shahid Shirodi Blovard, Kermanshah, Iran ,
3- Kermanshah, Iran
Abstract: (17136 Views)
Background: Falcaria vulgaris has different properties and it used as dietary and medicinal herb in the west of Iran. Previously, we showed that this plant has protective and repairing effect on gastric ulcer were demonstrated .The aim of present work was to investigate the effects of F. vulgaris extract on female rat's fertility.
Material and methods: In this Exprimental study Virgin female NMRI rats (160-190 gr) were used in three experiments. In each experiment, animal divided into two subgroups (n=8): control which received Distilled Water (DW) (2cc/kg) and case which received herb extract (150mg/kg) interaperitonealy. In first experiment, animals received single dose of extract or DW.
In second experiment، female rat received extract or DW in perimplantation period (day 1 to 5 of pregnancy) and in third experiment ( day 5 to 7 of pergnancy). In both experiments implantation sites and neonates were counted in three experiments. Data were analyzed by T-Test test and p<0.05 were considered significant.
Results: All three experiments showed significant differences between control and case groups in implantation sites and neonates number. This differences were more prominence in first and third experiment.
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