Volume 4, Issue 4 (Winter 2001)
J Arak Uni Med Sci 2001, 4(4): 15-18 |
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Moshfeghi K, Rafii M. Diagnostic Value of Reticulocyte Count Test in Dissociation of Iron Deficiency Anemia and Minor B Thalassemia. J Arak Uni Med Sci 2001; 4 (4) :15-18
URL: http://jams.arakmu.ac.ir/article-1-6680-en.html
URL: http://jams.arakmu.ac.ir/article-1-6680-en.html
1- Oncologist, Arak University of Medical Sciences, Arak, Iran.
2- Arak University of Medical Sciences, Arak, Iran.
2- Arak University of Medical Sciences, Arak, Iran.
Abstract: (2660 Views)
Introduction: Iron deficiency anemia is the most common type of anemia in the world and the most important disease which has overlapping diagnosis with it is & thalassemia minor. For diagnosis of theses two diseases, serum ferritin measurement and hemoglobin laboratories throughout the country now, finding some tests which are easier. More available and cheaper for different of these two mentioned diseases, are useful. Therefore in this article, reticulocyte counting test, after a short period of iron consumption, was evaluated.
Material and Method: This study is descriptive and cross-sectional. The sample population consists of 69 patient with hypochromic microcytic anemia which serum ferritin measurement, reticulocyte counting and hemoglobin electrophoresis for each of there were done. After 7 days treatment with oral iron tablet, reticulocyte counting test for each of them was done. If reticulocyte counting test had increased, the patient was considered as iron deficiency anemia, on the other hand, the results of reticulocyte count test was compared with serum ferritin test and hemoglobin electrophoresis results and then, sensitivity as well as specificity of mentioned test, were analysised.
Results: Sensitivity and specificity of mentioned test for iron deficiency anemia were 82 and 67 percent and in B thalassemia minor were 64 and 78 percent, respectively. These results show high sensitivity of this test for iron deficiency anemia and high specificity for B thalassemia minor.
Conclusion: It seems that, in circumstance which serum ferritin measurement and hemoglobin electrophoresis aren’t available, applying reticulocyte count test for deferenciation of these two diseases, is helpful.
Material and Method: This study is descriptive and cross-sectional. The sample population consists of 69 patient with hypochromic microcytic anemia which serum ferritin measurement, reticulocyte counting and hemoglobin electrophoresis for each of there were done. After 7 days treatment with oral iron tablet, reticulocyte counting test for each of them was done. If reticulocyte counting test had increased, the patient was considered as iron deficiency anemia, on the other hand, the results of reticulocyte count test was compared with serum ferritin test and hemoglobin electrophoresis results and then, sensitivity as well as specificity of mentioned test, were analysised.
Results: Sensitivity and specificity of mentioned test for iron deficiency anemia were 82 and 67 percent and in B thalassemia minor were 64 and 78 percent, respectively. These results show high sensitivity of this test for iron deficiency anemia and high specificity for B thalassemia minor.
Conclusion: It seems that, in circumstance which serum ferritin measurement and hemoglobin electrophoresis aren’t available, applying reticulocyte count test for deferenciation of these two diseases, is helpful.
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