Volume 12, Issue 4 (2-2010)
J Arak Uni Med Sci 2010, 12(4): 44-50 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Alizadeh S, Moshfeghi K, Kalantari M, Ebrahimi K. Lymph-node involvement and tumor markers in patients with breast cancer . J Arak Uni Med Sci 2010; 12 (4) :44-50
URL: http://jams.arakmu.ac.ir/article-1-365-en.html
URL: http://jams.arakmu.ac.ir/article-1-365-en.html
1- , kalantari_neda@yahoo.com
Abstract: (17469 Views)
Background: The existence of estrogen and progesterone receptors, p53, human epidermal receptor-2(HER-2) and cathepsin-D are among the prognostic markers for breast cancer. In this study, we investigated the relationship between these factors and lymph-node involvement. Materials and Methods: In this case-control analytic study, 105 patients with breast cancer were investigated. After detecting breast mass, surgical biopsy was done and the status of the estrogen and progesterone receptors, p53, HER-2, and cathepsin-D were studied. Collected data were registered in a checklist and were subjected to analysis. Results: There was no relationship between lymph-node involvement and estrogen and progesterone receptors, p53, cathepsin-D and HER-2. Conclusion: In order to get more precise results about hormonal receptors, p53, HER-2 and cathespin-D, a similar research with a larger sample size over a longer period of time is needed.
Keywords: Breast cancer, Cathepsin-D, Estrogen and progesterone receptor, HER-2 genes, Lymph Node, Prognosis, p53 genes
Subject:
Surgery
Received: 2009/06/28
Received: 2009/06/28
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
