Background: Due to the changing lifestyle in terms of nutrition and physical activity, obesity has become one of the major challenges to human health. The study of metabolic factors involved in this phenomenon plays an important role in preventing and treating the obesity. The aim of this study was to investigate the relationship between testosterone level and serum lipoproteins such as LDL and HDL with Body Mass Index (BMI), in different age groups of men in Golestan population.

Materials and Methods: In this case-control study, 183 men were randomly selected during 2012. Anthropometric measures (weight and height) were obtained according to standard methods, and BMI was calculated for each one. Data was analyzed using SPSS version 16. Pearson bivariate correlation test between groups and one-way Anova test was performed and p<0.05 being considered as significant.

Results: Data analysis showed a significant inverse correlation between BMI and serum testosterone level (p=0.005). In the study population, higher BMI was associated with increased LDL level (p=0.049) and also increasing age (p=0.011). In addition, an inverse relationship was observed between BMI and HDL levels that were not statistically significant (p=0.068).

Conclusion: The results of this study indicate that weight gain is associated with increased LDL and low testosterone serum level, and this relation is more meaningful in old men.