[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13, Number 2 (6-2010) ::
amuj 2010, 13(2): 75-82 Back to browse issues page
Evaluation of the drug synergistic and antibacterial effects of cuminum cyminum essential oil
Saed Daneshmandi, Neda Soleimani , Ali Akbar Pourfathollah, Morteza Sattari
M.S. , n.soleimani@modares.ac.ir
Abstract:   (13858 Views)
Background: Microbial infections are important challenges to health, and health care officials have major difficulties dealing with them especially regarding their antibiotic resistance. The main aim of this study was to evaluate drug synergistic and anti-bacterial effects of cuminum cyminum essential oil on some pathogen bacteria. Materials and Methods: Cuminum cyminum essential oil was extracted from its fruit. For evaluation of antibacterial effects of the essential oil, disc diffusion method through the measurement of the inhibitory zone diameter and micro-broth dilution for determining the minimum inhibitory concentration (MIC) on several standard bacteria were used. In evaluation of the synergistic and antagonistic effects, standard bacteria were cultured in the media containing essential oil, and antibiotic discs were, then, placed on it. Results: According to the results of disc diffusion test in Agar, cuminum cyminum essential oil, with a 44 mm inhibition zone, had the greatest antibacterial activity against bacillus cereus. It had the greatest positive co-action with gentamicin (10 µg) on escherichia coli. Conclusion: The results of this study indicate that cuminum cyminum essential oil alone or in combination with antimicrobial agents may be useful in treatment of bacterial infections. Additionally, this component can enhance the effect of some antibiotics this implies its application, especially in drug resistance cases.
Keywords: Antibiotic, Bacteria, Cuminum cyminum, Synergy
Full-Text [PDF 279 kb]   (3452 Downloads)    
Type of Study: Original Atricle | Subject: Basic Sciences
Received: 2010/01/3
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Daneshmandi S, Soleimani N, Pourfathollah A A, Sattari M. Evaluation of the drug synergistic and antibacterial effects of cuminum cyminum essential oil. amuj. 2010; 13 (2) :75-82
URL: http://amuj.arakmu.ac.ir/article-1-585-en.html
Volume 13, Number 2 (6-2010) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
Persian site map - English site map - Created in 0.055 seconds with 793 queries by yektaweb 3506