Volume 20, Issue 7 (10-2017)                   AMUJ 2017, 20(7): 89-97 | Back to browse issues page

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Moradi Farsani D, Naghibi K, Rezayinezhad Z. Studying the Effect of Intravenous Acetaminophen and Dexamethasone on Postoperative Headache after Cataract Surgery under Sedation and Topical anesthesia. AMUJ. 2017; 20 (7) :89-97
URL: http://amuj.arakmu.ac.ir/article-1-5263-en.html
Associate Professor, Anesthesiologist, Department of Anesthesiology, Isfahan University of Medical Sciences, Isfahan, Iran , naghibi@med.mui.ac.ir
Abstract:   (1019 Views)
Background: Up to now, there is no single opinion on how to control pain after surgery and clinical research in this area has been continuing. This study aimed to compare the effect of intravenous Acetaminophen, Dexamethasone and placebo on postoperative pain after cataract surgery under sedation and topical anesthesia.
Materials and Methods: In a clinical trial study, 120 patients undergoing cataract surgery under sedation and topical anesthesia were distributed into three equal groups. 10 minutes before the end of surgery, the first group received 0.01 mg/kg Dexamethasone, the second group received 15 mg/kg Acetaminophen and third group received the same volume on normal saline as placebo. Pain intensity and additional analgesic consumption were assessed during operation and recovery and compared between the three groups.
Results: In the three groups of Acetaminophen, Dexamethasone and control groups, 6, 10 and 18 patients had postoperative headache (16.7%, 27% and 47.4% respectively) and there was a significant difference between the three groups(p=0.014). Also, pain intensity was significantly higher in control group compared with other two groups from 30 minutes after arrival to the recovery room until 24 h postoperatively (p<0.05). Also, the incidence of headache was higher in Dexamethasone group compared with Acetaminophen group, but there was no statistical difference between the two groups in this regard (p>0.05).
Conclusion: Intravenous Acetaminophen administration is more effective than Dexamethasone and placebo to reduce pain and analgesic requirements after cataract surgery.

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Type of Study: Original Atricle | Subject: Anesthesia
Received: 2017/08/8 | Accepted: 2017/08/25 | Published: 2017/09/12

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