[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13, Issue 2 (6-2010) ::
AMUJ 2010, 13(2): 26-31 Back to browse issues page
Nitrofurantoin sensitivity in vancomycin resistant enterococcus
Omid Teimornejad , Ashraf Mohebi , Reza Hosseini
Associated Professor , mmmobarez@modares.ac.ir
Abstract:   (11742 Views)
Background Vancomycin resistant enterococcus (VRE) is the third major cause of nosocomial infections in hospitals after staphylococcus and E. coli. The aim of this study was to evaluate resistance pattern of VRE to the antibiotics recommended by CLSI. Materials and Methods: In this clinical trial, 833 enterococci, obtained from urine, wound, blood, and stool, were selectively collected from hospitals in Tehran. After verification of the VRE isolates through the use of 30µg vancomycin disc and agar dilution, VREs were isolated, and their inhibiting concentrations were determined. The sensitivity of these enterococci to antibiotics was assessed at CLSI’s M100 standard. Results: Of the 833 isolated enterococci, 4% had a high level of resistance to vancomycin, and 38.5% had a low level of resistance to vancomycin. Of the VREs, 8.5%, 85%, 50%, 42%, 94%, 30%, 70%, 24%, 6%, and 97% were resistant to vancomycin, ampicilin, erythromycin, tetracycline, rifampin, chloramphenicol, gentamicin, synercid, linozolid and penicillin, respectively. All these VRE isolates were sensitive to nitrofurantoin. Conclusion: In this study, all VRE isolates were sensitive to nitroforantoin, and this antibiotic, as a drug of choice for urinary tract infections, can also be recommended in the treatment of resistant enterococci.
Keywords: Clinical sample, nitrofurantoin, VRE
Full-Text [PDF 250 kb]   (1981 Downloads)    
Type of Study: Original Atricle | Subject: Infection
Received: 2009/11/7
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Teimornejad O, Mohebi A, Hosseini R. Nitrofurantoin sensitivity in vancomycin resistant enterococcus. AMUJ. 2010; 13 (2) :26-31
URL: http://amuj.arakmu.ac.ir/article-1-512-en.html

Volume 13, Issue 2 (6-2010) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
Persian site map - English site map - Created in 0.056 seconds with 799 queries by yektaweb 3600