Volume 19, Issue 7 (10-2016)                   AMUJ 2016, 19(7): 91-98 | Back to browse issues page

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Niazi F, Tehranipour M, Shahrokhabadi K. The effects of alcoholic leaf extract Ocimum basilicum on angiogenesis in chick chorioallantoic membrane. AMUJ. 2016; 19 (7) :91-98
URL: http://amuj.arakmu.ac.ir/article-1-4408-en.html
Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran , maryam_tehranipour@mshdiau.ac.ir
Abstract:   (2427 Views)

Background: Angiogenesis is an important biological processes of new blood vessels in many pathological stages of development and embryo development occurs and a complex and dynamic phenomenon that is needed for development and other physiological processes. This study aimed to investigate the effect of alcoholic Ocimum basilicum leaf extract on angiogenesis chick chorioallantoic membrane is done.

Materials and Methods: In this experimental study 40 Ross fertilized eggs were randomly divided into four groups: control, sham-exposed and experimental groups were divided. The second day of incubation the eggs window was opened. Eighth day of the alcoholic extract of basil doses of 50 and 150 mg/kg on chick chorioallantoic membrane was injected. On day 12, embryos length and weight and chorioallantoic membrane (CAM) was photographed by photostereomicroscope Then the numbers and lengths of vessels in special area on CAM were measured with Image J. analyzed through by t-test and ANOVA (P<0.05).

Results: The data does not show significant difference between embryos length and weight in sham compare to all experimental groups. In the study vessels number just with 150 mg/kg observed significant.

Conclusion: Alcoholic extract of basil is an increase in the number of vessels and in this sense the healing and growth processes associated with them as well as effective.

Full-Text [PDF 777 kb]   (762 Downloads)    
Type of Study: Original Atricle | Subject: Basic Sciences
Received: 2016/05/8 | Accepted: 2016/07/3 | Published: 2016/09/24

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