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:: Volume 18, Number 8 (11-2015) ::
amuj 2015, 18(8): 1-10 Back to browse issues page
Determining the Frequency of Nasal Carriage and Virulence of S. aureus Isolated from Nose of Patients Admitted to Intensive Care Units at Vali - Asr Hospital in Arak, 2014
Leila Akhtar Danesh , Zeinab Saiedi nejad, Hossein Sarmadian, Alireza Amouzandeh-Nobaveh, Aliasghar Farazi, Ehsanollah Ghaznavi-Rad
Department of Microbiology and Immunology, Arak University of Medical Sciences, Arak, Iran
Abstract:   (3079 Views)

Background: Staphylococcus aureus is one of the important pathogens can cause infections in hospitals specially in intensive care units (ICU). It seems that nasal carriage is important risk factor for developing l infection at ICU units. This study was designed to investigate the frequency of S. aureus nasal carriage and its virulence in patients admitted to ICU units in Vali-Asr hospital at Arak university of medical sciences.

Materials and Methods: In this cross-sectional study, nasal swab samples were obtained from all the patients hospitalized in ICU unit of Vali-Asr hospital from July-December 2014 at admission. After identification, methicillin resistance and the frequency of pvl and acme genes determined by PCR. Demographic data were collected using questionnaire and were analysed using SPSS 20 software.

Results: Out of 390 patients, 81(20.8%) and 31(12.9) patients had been colonized with MSSA and MRSA, respectively. The result of culture was negative for 278 patients (71.3%). 77.4% of MRSA and 54.3% of MSSA isolates were positive for acme gene. Also, 11.11% of and 6.45% of MSSA MRSA isolates were positive for pvl gene.

Conclusion: The application of medical supportive devices like cv line, ventilator, history of surgery operation and antibiotic use significantly was associated with S. aureus nasal carriage. High prevalence of S.aureus shows that these bacteria settled in the hospital. Hence, infection control measures must be performed to reduce the risk of hospital infection.

Keywords: S. aureus, Nasal carriage, Nosocomial infection, ICU
Full-Text [PDF 831 kb]   (518 Downloads)    
Type of Study: Original Atricle | Subject: Infection
Received: 2015/04/27 | Accepted: 2015/07/14 | Published: 2015/10/25
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Akhtar Danesh L, Saiedi nejad Z, Sarmadian H, Amouzandeh-Nobaveh A, Farazi A, Ghaznavi-Rad E. Determining the Frequency of Nasal Carriage and Virulence of S. aureus Isolated from Nose of Patients Admitted to Intensive Care Units at Vali - Asr Hospital in Arak, 2014. amuj. 2015; 18 (8) :1-10
URL: http://amuj.arakmu.ac.ir/article-1-3660-en.html
Volume 18, Number 8 (11-2015) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
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