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:: Volume 12, Number 4 (2-2010) ::
amuj 2010, 12(4): 44-50 Back to browse issues page
Lymph-node involvement and tumor markers in patients with breast cancer
ShabanAli Alizadeh, Kamran Moshfeghi, Mssoumeh Kalantari , Khadijeh Ebrahimi
general physician , kalantari_neda@yahoo.com
Abstract:   (13000 Views)
Background: The existence of estrogen and progesterone receptors, p53, human epidermal receptor-2(HER-2) and cathepsin-D are among the prognostic markers for breast cancer. In this study, we investigated the relationship between these factors and lymph-node involvement. Materials and Methods: In this case-control analytic study, 105 patients with breast cancer were investigated. After detecting breast mass, surgical biopsy was done and the status of the estrogen and progesterone receptors, p53, HER-2, and cathepsin-D were studied. Collected data were registered in a checklist and were subjected to analysis. Results: There was no relationship between lymph-node involvement and estrogen and progesterone receptors, p53, cathepsin-D and HER-2. Conclusion: In order to get more precise results about hormonal receptors, p53, HER-2 and cathespin-D, a similar research with a larger sample size over a longer period of time is needed.
Keywords: Breast cancer, Cathepsin-D, Estrogen and progesterone receptor, HER-2 genes, Lymph Node, Prognosis, p53 genes
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Subject: Surgery
Received: 2009/06/28
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Alizadeh S, Moshfeghi K, Kalantari M, Ebrahimi K. Lymph-node involvement and tumor markers in patients with breast cancer . amuj. 2010; 12 (4) :44-50
URL: http://amuj.arakmu.ac.ir/article-1-365-en.html
Volume 12, Number 4 (2-2010) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
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