Volume 17, Issue 8 (11-2014)                   J Arak Uni Med Sci 2014, 17(8): 35-43 | Back to browse issues page

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Ghandy A R, Alimoradian A. Effect of Parenteral Calcitonin on Cortex Healing up & Accidents of Distal Radius’ Fracture in Women with More Than 60 Years Old Referring to Arak Valiasr Hospital . J Arak Uni Med Sci. 2014; 17 (8) :35-43
URL: http://amuj.arakmu.ac.ir/article-1-3116-en.html
Assistant Professor, - Department of Pharmacology, Arak University of Medical Sciences, Arak, Iran , Dr.alimoradian@arakmu.ac.ir
Abstract:   (3332 Views)

Background: The distal radius’ fracture is one of the most prevalent fractures in menopause women. Because of no delisery of an exact dosage by inhalation calcitonin, the effect of a systemic form such as parenteral on healing up of this area was investigated.

Materials and Methods: This study was a prospective cohort on 44 women 60 years-old with distal radius’ fracture divided into 2 equal groups of control and treatment (parenteral calcitonin, just after operation, 100 I.U/day during 10 days consecutive of each month for 3 months). The rate of improvement, hand ability and stiffness of joints of hand fingers and wrist according with physical examination, time of cortex healing up, level of alkaline phosphatase, calcium and phosphor serum levels and rate of osteoporosis accord to radiography indexes.

Results: The rate of osteoporosis and pain was less tham that of control group. Prevention of osteoporosiss and the cortex healirg was significaltly more than that of control group. The hard activity (Mayo Wrist index) and ability of ceetching of objects was better in calcitonin group. There were not any significant effects of calcitonin on level of alkalire phosphatose, calcium and phosphor us serum levels.

Conclusion: Calcitonin especially with calcium supplements can accelerate the improvement of distal radius’ fracture. Then patients will tolerate fewer problems at convalescence period.

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Type of Study: Original Atricle | Subject: Ortopedia
Received: 2014/08/10 | Accepted: 2014/10/22 | Published: 2014/10/22

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