Volume 12, Number 2 (9-2009)                   amuj 2009, 12(2): 9-16 | Back to browse issues page


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Pazoki S, Noroozi A, Shadman A H. Comparison effect of different doses of Ketamine with Pethedine in reducing postoperative shivering after cesarean section. amuj. 2009; 12 (2) :9-16
URL: http://amuj.arakmu.ac.ir/article-1-304-en.html

Assistant perofessor , Shirin_Pazoki @ yahoo.com
Abstract:   (14128 Views)
Background: Postoperative shivering is a common problem with multiple complications. This study was compared effect of low doses of Ketamine with Pethidine for controlling postoperative shivering. Methods and Materials: This clinical trial was done on 189 elective cesarean section with ASA class I or II who had postoperative shivering. Patients with grade 2 or higher were divided in three groups and were injected 0.3mg/kg Ketamine and 0.5mg/kg Pethidine intravenously. In 5th and 10th minutes after injection, they were investigated for shivering intensity. Results: After 5 minute of injection drugs rate and intensity of shivering in Pethedine group was less than ketamine group. Ketamine with 0.5 mg/kg was more effective than 0.3mg/kg dose of it and Ketamine(p=0.041). In group with 0.5mg/kg dose of Ketamine, rate and intensity of postoperative shivering was more reduce than group with 0.3mg/kg of it in recovery(p=0/007). In Pethedine group rate and intersity of shivering was more reduce then 0.5mg/kg dose of Ketamine(p<0/001). This demonstrated that Pethedine is more effective than Ketamine. Conclusion: Although 0.5mg/kg dose of Ketamine has considerable effect on control of shivering but Pethedine is still a better choice for this side effect.
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Subject: Anesthesia
Received: 2009/05/5

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