Volume 16, Issue 10 (1-2014)                   J Arak Uni Med Sci 2014, 16(10): 70-75 | Back to browse issues page

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kazemi saleh D, Jozani Z, Assar O, Lotfian I. The Effect of Vitamin D Deficiency on Coronary Artery Stenosis Severity in Angioplasty Patients in Baqiatallah Hospital in 2013. J Arak Uni Med Sci. 2014; 16 (10) :70-75
URL: http://amuj.arakmu.ac.ir/article-1-2483-en.html
Cardiosurgeon, Atherosclerosis Research Center, Baqiatallah University of Medical Sciences, Tehran, Iran , omassar@gmail.com
Abstract:   (5940 Views)

Background: Cardiac accidents due to Coronary Artery Disease are the most common cause of mortality in the world. On the other hand, vitamin D deficiency is known as an emerging risk factor of this disease. Considering the high prevalence of vitamin D deficiency in Iran we investigated the prevalence of vitamin D deficiency in angioplasty patients, effect of gender and its relationship with Coronary Artery Disease severity.

Materials and Methods: In this cross sectional study serum level of 25(OH) D3 in was measured in 149 patients undergoing PCI between May and September 2013 in Baqiatallah hospital. Patients with renal failure (Cr>2mg/dl), liver disease, and those treated with glucocorticoids or anti-epileptic drugs were excluded. Data were analyzed with SPSS 21 software. Chi-square and T-Test were used and P value<0.05 was considered statistically significant.

Results: The prevalence of vitamin D deficiency in patients was 77.2% (men 86% and women 62.5%) (p=0.0005). Vitamin D deficiency severity was related to the number of involved vessels in men (p=0.046). Vitamin D deficiency was related with stent length in patients with right coronary angioplasty (p=0.041).

Conclusion: The effect of vitamin D deficiency on coronary artery disease seems to be different in men and women. Complementary studies are needed to elucidate this issue further.

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Type of Study: Original Atricle | Subject: Cardiology
Received: 2013/08/24 | Accepted: 2013/12/3 | Published: 2013/12/18

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