Volume 16, Issue 10 (1-2014)                   J Arak Uni Med Sci 2014, 16(10): 84-92 | Back to browse issues page

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Vosadi E, Barzegar H, Borjianfard M. The Effect of Endurance Training and High-Fat Diet in Brain-Derived Neurotrophic Factor (BDNF) in the Male Adult Rat Hippocampus. J Arak Uni Med Sci. 2014; 16 (10) :84-92
URL: http://amuj.arakmu.ac.ir/article-1-2442-en.html
PhD Student, Department of Sport Physiology, Tehran University, Tehran, Iran , e.vosadi@ut.ac.ir
Abstract:   (14740 Views)

Introduction: This study was to examine the effects of endurance training and high-fat diet in brain-derived neurotrophic factor (BDNF) in the male adult rat hippocampus.

Materials and Methods: Twenty eight Wistar rats were divided into four groups: (1) Regular diet-sedentary (RD-Sed), (2) Regular diet-Exercise (RD-Exe), (3) HF-sedentary (HF-Sed), and (4) HF- Exercise (HF- Exe) RD-Sed group was regarded as control. Animals in exercise groups received 8-wk endurance training and animals in HF groups were exposed to the HF diet for 8-wk. Hippocampal BDNF protein was assessed using commercial ELISA kits and the data were analyzed by one-way ANOVA. Statistical differences were considered significant at p<0.05.

Results: The results showed that the endurance training had no significant increase in BDNF protein level comparison with the RD-Sd and HF-Sed groups moreover the high-fat diet had no significant effect in BDNF protein level.

Conclusion: According to results of present study, looks applications of endurance training can increase amount of hippocampus BDNF protein level.

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Type of Study: Original Atricle | Subject: General
Received: 2013/07/27 | Accepted: 2013/12/3 | Published: 2013/12/18

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