Volume 14, Issue 7 (Brucellosis Supplement 2012)                   J Arak Uni Med Sci 2012, 14(7): 95-99 | Back to browse issues page

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Parsa N, Almasi-Hashiani A. Brucella bacterium induces infection and human cancers: Review Article. J Arak Uni Med Sci. 2012; 14 (7) :95-99
URL: http://amuj.arakmu.ac.ir/article-1-1589-en.html
, nzparsa@yahoo.com
Abstract:   (11161 Views)
Human Brucellosis is an infectious disease caused by Brucella bacteria. An average of 150 cases of brucellosis among 330 million people is reported in the USA each year. This bacterium is small, gram-negative rods that grow in phagocytes. They primarily cause diseases among different animals and humans become infected when is in contact with animals or their products. Brucella can cause various symptoms in humans which is similar to human influenza. Brucellosis is diagnosed in a laboratory by finding Brucella organisms in samples of blood or bone marrow or to detect antibodies against the bacteria in two blood samples, collected 2 weeks apart. Depending on severity of illness, recovery may take as long as several months. There is no vaccine available for human except live vaccines and that should be consulted to a health care provider. DNA findings for Brucella species in the index patients focused our attention on revealed human cancers. Also, granalomatous inflammation of testes and medulloblastomas has been linked to chronic Brucellosis infection which could be similar to Helicobacter pylori that is associated with gastric tumor formation. More scientific investigation is needed to properly address the connection of Brucella with other human malignancies.
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Type of Study: Original Atricle | Subject: Infection
Received: 2012/03/12 | Accepted: 2012/03/18

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