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:: Volume 15, Number 3 (August 2012) ::
amuj 2012, 15(3): 8-14 Back to browse issues page
The study of the antibiotic resistance pattern of Pseudomonas aeruginosa strains isolated from hospitalized patients in Arak
Bahare Rahimi, Mana Shojapour, Abdorrahim Sadeghi , Ahmad Ali Pourbabayi
Assistant professor Arak University of Medical Sciences
Abstract:   (10601 Views)
Background: Pseudomonas aeruginosa is a human opportunistic pathogen which is considered one of the agents causing nosocamial infection. Recent studies have reported increased resistance of Pseudomonas aeruginosa to imipenem. The aim of this study was to determine resistance to antipseudomonal antibiotics including imipenem in Pseudomonas aeruginosa strains. Materials and Methods: In this cross-sectional study, 100 Pseudomonas aeruginosa strains obtained from clinical samples of patients in hospitals in Arak, Iran, were identified and isolated through microbiological methods, including Gram staining, oxidase test, Indol test, and oxidative-fermentative test. Then antibiotic susceptibility test was performed for imipenem, meropenem, gentamicin, amikacin, ciprofloxacin, and ceftazidime by disk diffusion method according to NCCLS (National Committee for Clinical Laboratory Standards) .Minimum inhibitory concentration (MIC) was done for determining imipenem-resistant strains Results: Antibiotic susceptibility test showed that resistance rates to imipenem, meropenem, gentamicin, amikacin, ciprofloxacin, and ceftazidime were 35%, 35%, 14%, 9%, 23% and 15%, respectively. Also, MIC test showed that 30 strains were resistant to imipenem, 27 to ceftazidime, 35 to cefepime, and 35 to ciprofloxacin. Conclusion: The results of this study indicated a high rate of antibiotics resistant of Pseudomonas aeroginosa strains to different antibiotic groups. Therefore, new and more effective methods should be found for controlling Pseudomonas infections and preventing the outbreak of its antibiotic-resistant strains.
Keywords: Antibiotic, imipenem resistance, Pseudomonas aeruginosa
Full-Text [PDF 252 kb]   (2157 Downloads)    
Type of Study: Original Atricle | Subject: Infection
Received: 2011/08/7 | Accepted: 2011/10/27
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Rahimi B, Shojapour M, Sadeghi A, Pourbabayi A A. The study of the antibiotic resistance pattern of Pseudomonas aeruginosa strains isolated from hospitalized patients in Arak. amuj. 2012; 15 (3) :8-14
URL: http://amuj.arakmu.ac.ir/article-1-1264-en.html
Volume 15, Number 3 (August 2012) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
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