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:: Volume 15, Issue 1 (April-May 2012) ::
amuj 2012, 15(1): 116-126 Back to browse issues page
Effect of omega3 on vasomotor disorders in menopausal women
Razieh Moghadam , Giti Ozgoli , Behnaz Molayi , Hajifaraji Majid , Hamid Soori , Kiandokht Ghanati
MSM International Branch of Shahid Beheshti University of Medical Sciences. , gozgoli@ahoo.comy
Abstract:   (10607 Views)
Background: Vasomotor disorders are one of the most painful menopausal complications that negatively affect the quality of life in menopausal women. This study investigated the effects of omega3 fatty acid on vasomotor disorders in menopausal women. Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial study was done on 83 menopausal women aged 45-60 years that had met the inclusion criteria. The participants were randomly assigned to omega3 or placebo groups. Fish oil capsules (containing 300 mg of omega3) or placebo capsules were prescribed to the participants one capsule a day for 8 weeks. Of the 83 patients enrolled, 68 completed the study (omega3 supplement, n=34 placebo n=34). Data collection was done through demographic questionnaire, daily self report, and food frequency questionnaire (FFQ). Data were analyzed by t-test, Chi square, Fiedman, and Mann-Whitney tests using SPSS software version 18. Results: After 8 weeks of intervention, there was a significant difference in HF frequency (p=0.003) and nightsweats frequency (p=0.001) between the two groups. There was no significant difference in HF intensity between the two groups (p=0.2) but reduction of nightsweats intensity was significant between the two groups (p=0.003). Conclusion: Omega3 affected the reduction of HF frequency and nightsweats frequency and intensity but it did not have a significant effect on the severity of HF.
Keywords: Hot flashes, Menopause, Omeg-3 fatty acids, Vasomotor symptoms
Full-Text [PDF 348 kb]   (1646 Downloads)    
Subject: Obstetrics & Gynocology
Received: 2011/03/14 | Accepted: 2011/06/1
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Moghadam R, Ozgoli G, Molayi B, Majid H, Soori H, Ghanati K. Effect of omega3 on vasomotor disorders in menopausal women. amuj. 2012; 15 (1) :116-126
URL: http://amuj.arakmu.ac.ir/article-1-1095-en.html
Volume 15, Issue 1 (April-May 2012) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
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