Volume 15, Number 1 (April-May 2012)                   amuj 2012, 15(1): 10-17 | Back to browse issues page


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Baharara S, Zahedifar Z, Haddad F, Mahdavi shari N. Effect of green tea on repressing chromosomal damage induced by cellphone (940MHz) waves in bone marrow polychromatic erythrocytes of male Balb/C mice. amuj. 2012; 15 (1) :10-17
URL: http://amuj.arakmu.ac.ir/article-1-1001-en.html

, baharara@yahoo.com
Abstract:   (9421 Views)
Background: Green tea due to its antioxidant properties can prevent some types of chromosomal damage. In this study, the effects of green tea on repressing chromosomal aberrations induced by cell phone waves in bone marrow polychromatic erythrocytes of male Balb/C mice were investigated. Materials and Methods: In this experimental study, 40 adult male Balb/C mice were randomly divided into five groups: control (natural conditions), sham exposed (no exposure to cell phone waves in vitro), experimental group 1 (exposure to cell phone waves), and experimental group 2 (intraperitoneal injection of 100 mg/kg dose of green tea extract for 5 days and exposure to cell phone waves), and experimental group 3 (intraperitoneal injection of 200 mg/kg dose of green tea extract for 5 days and exposure to cell phone waves). Micronucleus test was run in all groups. Data were analyzed by ANOVA and Tukey tests using SPSS software (p<0.05). Results: The mean number of micronucleus in polychromatic erythrocytes of the sham group (3.47± 0.253) compared with control group (3.43 ± 0.605) did not show a significant difference (p> 0.05), whereas the mean micronucleus frequency in the experimental group 1 (5.64±0.308) increased significantly. However, the mean micronucleus frequency in experimental group 2 (0.92 ± 0.129) and experimental group 3 (0.55 ± 0.046) compared with the control and sham exposed groups decreased significantly (p = 0.001). Conclusion: Cell phones microwaves (940 MHz) induce chromosomal aberrations in bone marrow polychromatic erythrocytes of male Balb/C mice, but green tea has inhibitory effects and reduces chromosomal damage.
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Type of Study: Original Atricle | Subject: Basic Sciences
Received: 2011/01/7 | Accepted: 2011/04/6

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