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:: Volume 14, Issue 6 (February-March 2012) ::
amuj 2012, 14(6): 19-26 Back to browse issues page
Comparison of the serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous in individuals with major depression and schizophrenics with healthy subjects
Hamid Reza Jamilian , Kamran Bagherzadeh , Zeinab Nazeri
M.D. , mjamilian@yahoo.com
Abstract:   (10180 Views)
Background: Major depression is one of the most prevalent psychiatric diseases, whereas schizophrenia is one of the worst human diseases. Therefore, finding low-cost treatment methods with few side effects can be of great help to patients. The present study was done to compare the serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous in individuals with major depression and schizophrenics with healthy subjects. Materials and Methods: In this cross-sectional study, serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous were assessed in 100 major depressive, 100 schizophrenic, and 100 healthy subjects. Subjects with a history of renal failure, hepatic failure, parathyroid disease, and consumption of vitamin D, parathyroid hormone, calcium, and phosphorous supplements were excluded from the study. SPSS software version 15 was used for data analysis. Results: Depression was accompanied with decreased serum levels of vitamin D and increased serum levels of parathyroid hormone (p>0.001, p=0.01), but there was not a significant difference between depression and healthy subjects in calcium and phosphorous serum levels (p=0.69, p=0.15). Schizophrenia presented a significant correlation with decreased serum levels of vitamin D and phosphorous (p>0.001, p=0.01), but there was not a significant difference between schizophrenic and healthy subjects in calcium and parathyroid hormone serum levels (p=0.47, p=0.67). Conclusion: Since depression and schizophrenia are accompanied by decreased serum level of vitamin D, consumption of supplementary vitamin D can be helpful in the treatment of these patients.
Keywords: Calcium, Depression, Parathyroid hormone, Phosphorous, Schizophrenia, Vitamin D
Full-Text [PDF 1753 kb]   (1935 Downloads)    
Type of Study: Original Atricle | Subject: psychology
Received: 2010/07/6
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Jamilian H R, Bagherzadeh K, Nazeri Z. Comparison of the serum levels of vitamin D, parathyroid hormone, calcium, and phosphorous in individuals with major depression and schizophrenics with healthy subjects. amuj. 2012; 14 (6) :19-26
URL: http://amuj.arakmu.ac.ir/article-1-786-en.html
Volume 14, Issue 6 (February-March 2012) Back to browse issues page
مجله دانشگاه علوم پزشکی اراک Arak Medical University Journal
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